SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2oz4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)		 2oz4 FAB FRAGMENT, HEAVY
CHAIN
(Mus
musculus) 		4 / 4 THR H 118
PRO H 148
THR H 117
PRO H 119
 None
 1.27A 1dsdC-2oz4H:
undetectable		 1dsdC-2oz4H:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)		 2oz4 FAB FRAGMENT, HEAVY
CHAIN
(Mus
musculus) 		4 / 4 THR H 118
PRO H 148
THR H 117
PRO H 119
 None
 1.27A 1dsdC-2oz4H:
undetectable		 1dsdC-2oz4H:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_A_CAMA503_0
(CYTOCHROME P450-CAM)		 2oz4 FAB FRAGMENT, HEAVY
CHAIN
(Mus
musculus) 		4 / 8 TYR H  27
THR H  98
LEU H   4
VAL H  72
 None
 1.07A 1dz9A-2oz4H:
undetectable		 1dz9A-2oz4H:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 2oz4 INTERCELLULAR
ADHESION MOLECULE 1
(Homo
sapiens) 		4 / 8 VAL A 295
VAL A 288
VAL A 303
LEU A 363
 None
 0.87A 1igxA-2oz4A:
undetectable		 1igxA-2oz4A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_B_CAMB1420_0
(CYTOCHROME P450-CAM)		 2oz4 FAB FRAGMENT, HEAVY
CHAIN
(Mus
musculus) 		4 / 8 TYR H  27
THR H  98
LEU H   4
VAL H  72
 None
 1.12A 1o76B-2oz4H:
undetectable		 1o76B-2oz4H:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_A_SALA710_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 2oz4 INTERCELLULAR
ADHESION MOLECULE 1
(Homo
sapiens) 		4 / 7 VAL A 295
VAL A 303
LEU A 329
LEU A 363
 None
 0.86A 1pthA-2oz4A:
undetectable		 1pthA-2oz4A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_B_SALB711_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 2oz4 INTERCELLULAR
ADHESION MOLECULE 1
(Homo
sapiens) 		4 / 7 VAL A 295
VAL A 303
LEU A 329
LEU A 363
 None
 0.85A 1pthB-2oz4A:
undetectable		 1pthB-2oz4A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_1
(POL POLYPROTEIN)		 2oz4 FAB FRAGMENT, HEAVY
CHAIN
INTERCELLULAR
ADHESION MOLECULE 1
(Homo
sapiens;
Mus
musculus) 		5 / 8 ASP A 375
ILE A 414
GLY A 415
GLY H  57
ILE H  51
 None
 1.25A 1sguA-2oz4A:
undetectable		 1sguA-2oz4A:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 2oz4 FAB FRAGMENT, HEAVY
CHAIN
(Mus
musculus) 		4 / 7 TYR H  27
THR H  98
LEU H   4
VAL H  72
 None
 1.05A 1t85A-2oz4H:
undetectable		 1t85A-2oz4H:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_A_CAMA1416_0
(CYTOCHROME P450-CAM)		 2oz4 FAB FRAGMENT, HEAVY
CHAIN
(Mus
musculus) 		4 / 8 TYR H  27
THR H  98
LEU H   4
VAL H  72
 None
 1.03A 1uyuA-2oz4H:
undetectable		 1uyuA-2oz4H:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)		 2oz4 FAB FRAGMENT, HEAVY
CHAIN
(Mus
musculus) 		4 / 8 TYR H  27
THR H  98
LEU H   4
VAL H  72
 None
 1.10A 1uyuB-2oz4H:
undetectable		 1uyuB-2oz4H:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)		 2oz4 FAB FRAGMENT, HEAVY
CHAIN
(Mus
musculus) 		4 / 7 TYR H  27
THR H  98
LEU H   4
VAL H  72
 None
 1.02A 1yrcA-2oz4H:
undetectable		 1yrcA-2oz4H:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 2oz4 FAB FRAGMENT, HEAVY
CHAIN
(Mus
musculus) 		4 / 6 TYR H  27
THR H  98
LEU H   4
VAL H  72
 None
 1.00A 2feuA-2oz4H:
undetectable		 2feuA-2oz4H:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)		 2oz4 FAB FRAGMENT, HEAVY
CHAIN
(Mus
musculus) 		4 / 7 TYR H  27
THR H  98
LEU H   4
VAL H  72
 None
 1.01A 2feuB-2oz4H:
undetectable		 2feuB-2oz4H:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRL_A_DXTA1211_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 2oz4 INTERCELLULAR
ADHESION MOLECULE 1
(Homo
sapiens) 		5 / 12 PRO A 197
THR A 277
VAL A 278
LEU A 227
ILE A 280
 None
 1.34A 2xrlA-2oz4A:
undetectable		 2xrlA-2oz4A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 2oz4 FAB FRAGMENT, HEAVY
CHAIN
(Mus
musculus) 		4 / 6 TYR H  27
THR H  98
LEU H   4
VAL H  72
 None
 1.06A 2zuiA-2oz4H:
undetectable		 2zuiA-2oz4H:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 2oz4 FAB FRAGMENT, HEAVY
CHAIN
(Mus
musculus) 		4 / 7 TYR H  27
THR H  98
LEU H   4
VAL H  72
 None
 1.04A 2zwtA-2oz4H:
undetectable		 2zwtA-2oz4H:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 2oz4 FAB FRAGMENT, HEAVY
CHAIN
(Mus
musculus) 		4 / 7 TYR H  27
THR H  98
LEU H   4
VAL H  72
 None
 1.04A 2zwuA-2oz4H:
undetectable		 2zwuA-2oz4H:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 2oz4 FAB FRAGMENT, HEAVY
CHAIN
(Mus
musculus) 		4 / 7 TYR H  27
THR H  98
LEU H   4
VAL H  72
 None
 1.01A 3fwfA-2oz4H:
undetectable		 3fwfA-2oz4H:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 2oz4 FAB FRAGMENT, HEAVY
CHAIN
(Mus
musculus) 		4 / 7 TYR H  27
THR H  98
LEU H   4
VAL H  72
 None
 1.01A 3fwfB-2oz4H:
undetectable		 3fwfB-2oz4H:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 2oz4 FAB FRAGMENT, HEAVY
CHAIN
(Mus
musculus) 		4 / 7 TYR H  27
THR H  98
LEU H   4
VAL H  72
 None
 1.04A 3fwjA-2oz4H:
undetectable		 3fwjA-2oz4H:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KM6_B_EAAB222_1
(GLUTATHIONE
S-TRANSFERASE P)		 2oz4 INTERCELLULAR
ADHESION MOLECULE 1
(Homo
sapiens) 		5 / 9 PHE A 243
VAL A 218
VAL A 236
ASN A 240
GLY A 239
 None
None
None
NAG  A1240 (-1.8A)
None
 1.47A 3km6B-2oz4A:
undetectable		 3km6B-2oz4A:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)		 2oz4 FAB FRAGMENT, HEAVY
CHAIN
(Mus
musculus) 		4 / 7 TYR H  27
THR H  98
LEU H   4
VAL H  72
 None
 1.00A 3l63A-2oz4H:
undetectable		 3l63A-2oz4H:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2oz4 FAB FRAGMENT, HEAVY
CHAIN
(Mus
musculus) 		4 / 7 TYR H  27
THR H  98
LEU H   4
VAL H  72
 None
 1.03A 3wrhA-2oz4H:
undetectable		 3wrhA-2oz4H:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2oz4 FAB FRAGMENT, HEAVY
CHAIN
(Mus
musculus) 		4 / 7 TYR H  27
THR H  98
LEU H   4
VAL H  72
 None
 1.03A 3wrjA-2oz4H:
undetectable		 3wrjA-2oz4H:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2oz4 FAB FRAGMENT, HEAVY
CHAIN
(Mus
musculus) 		4 / 7 TYR H  27
THR H  98
LEU H   4
VAL H  72
 None
 1.00A 3wrlA-2oz4H:
undetectable		 3wrlA-2oz4H:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 2oz4 FAB FRAGMENT, HEAVY
CHAIN
(Mus
musculus) 		4 / 7 TYR H  27
THR H  98
LEU H   4
VAL H  72
 None
 1.02A 3wrlE-2oz4H:
undetectable		 3wrlE-2oz4H:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2oz4 FAB FRAGMENT, HEAVY
CHAIN
(Mus
musculus) 		4 / 7 TYR H  27
THR H  98
LEU H   4
VAL H  72
 None
 1.01A 3wrmA-2oz4H:
undetectable		 3wrmA-2oz4H:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)		 2oz4 FAB FRAGMENT, HEAVY
CHAIN
(Mus
musculus) 		4 / 7 TYR H  27
THR H  98
LEU H   4
VAL H  72
 None
 1.03A 3wrmF-2oz4H:
undetectable		 3wrmF-2oz4H:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_C_ECNC403_1
(FLAVOHEMOGLOBIN)		 2oz4 INTERCELLULAR
ADHESION MOLECULE 1
(Homo
sapiens) 		5 / 9 THR A 274
LEU A 194
VAL A 208
VAL A 223
LEU A 225
 None
 1.02A 4g1bC-2oz4A:
undetectable		 4g1bC-2oz4A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4E_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2oz4 FAB FRAGMENT, HEAVY
CHAIN
(Mus
musculus) 		4 / 8 TYR H  27
THR H  98
LEU H   4
VAL H  72
 None
 1.03A 4l4eA-2oz4H:
undetectable		 4l4eA-2oz4H:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4F_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2oz4 FAB FRAGMENT, HEAVY
CHAIN
(Mus
musculus) 		4 / 8 TYR H  27
THR H  98
LEU H   4
VAL H  72
 None
 1.02A 4l4fA-2oz4H:
undetectable		 4l4fA-2oz4H:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 2oz4 FAB FRAGMENT, HEAVY
CHAIN
(Mus
musculus) 		5 / 12 LEU H 160
VAL H 182
ILE H 211
LEU H 139
VAL H 207
 None
 1.11A 4y0qA-2oz4H:
undetectable		 4y0qA-2oz4H:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L2T_A_6ZZA900_2
(CYCLIN-DEPENDENT
KINASE 6)		 2oz4 FAB FRAGMENT, HEAVY
CHAIN
INTERCELLULAR
ADHESION MOLECULE 1
(Homo
sapiens;
Mus
musculus) 		3 / 3 LYS H  99
GLN A 436
ASN A 397
 None
 0.71A 5l2tA-2oz4H:
undetectable		 5l2tA-2oz4H:
21.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MTH_A_ACTA302_0
(ANTIBODY FAB HEAVY
CHAIN)		 2oz4 FAB FRAGMENT, HEAVY
CHAIN
(Mus
musculus) 		5 / 5 SER H 113
ALA H 115
PHE H 147
LEU H 171
ASP H 174
 None
 0.35A 5mthA-2oz4H:
27.8		 5mthA-2oz4H:
80.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TL8_A_X2NA502_1
(PROTEIN CYP51)		 2oz4 FAB FRAGMENT, HEAVY
CHAIN
(Mus
musculus) 		5 / 12 ALA H  16
PHE H 147
TYR H 146
LEU H 109
THR H  87
 None
 1.20A 5tl8A-2oz4H:
undetectable		 5tl8A-2oz4H:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2oz4 FAB FRAGMENT, HEAVY
CHAIN
(Mus
musculus) 		4 / 7 TYR H  27
THR H  98
LEU H   4
VAL H  72
 None
 1.02A 5wk9A-2oz4H:
undetectable		 5wk9A-2oz4H:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_0
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 2oz4 INTERCELLULAR
ADHESION MOLECULE 1
FAB FRAGMENT, HEAVY
CHAIN
(Homo
sapiens;
Mus
musculus) 		5 / 12 ASN A 397
PRO A 400
THR H  53
ILE H  54
PHE H  32
 None
 1.28A 6j20A-2oz4A:
undetectable		 6j20A-2oz4A:
21.94