SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2oz8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_C_DVAC6_0
(GRAMICIDIN A)		 2oz8 MLL7089 PROTEIN
(Mesorhizobium
japonicum) 		3 / 3 ALA A 204
VAL A 209
TRP A 242
 None
 0.71A 1av2C-2oz8A:
undetectable
1av2D-2oz8A:
undetectable		 1av2C-2oz8A:
4.78
1av2D-2oz8A:
4.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4Y_A_TPVA501_1
(PROTEIN (HIV-1
PROTEASE))		 2oz8 MLL7089 PROTEIN
(Mesorhizobium
japonicum) 		5 / 10 LEU A 219
ASP A 223
ASP A 194
GLY A 294
ILE A 293
 None
 0.98A 1d4yA-2oz8A:
undetectable		 1d4yA-2oz8A:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7W_B_MTXB301_1
(PTERIDINE REDUCTASE)		 2oz8 MLL7089 PROTEIN
(Mesorhizobium
japonicum) 		5 / 11 SER A 292
ASP A 223
LEU A 251
LEU A 233
HIS A 230
 None
None
None
None
SO4  A 388 (-3.9A)
 1.23A 1e7wB-2oz8A:
undetectable		 1e7wB-2oz8A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KNY_B_KANB559_1
(KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE)		 2oz8 MLL7089 PROTEIN
(Mesorhizobium
japonicum) 		4 / 8 GLU A 315
LYS A 163
GLU A 249
GLU A 222
 None
 1.08A 1knyA-2oz8A:
undetectable
1knyB-2oz8A:
undetectable		 1knyA-2oz8A:
21.96
1knyB-2oz8A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_1
(GLYCINE
N-METHYLTRANSFERASE)		 2oz8 MLL7089 PROTEIN
(Mesorhizobium
japonicum) 		3 / 3 ARG A  17
ASP A 194
ASN A 246
 None
 0.80A 1nbhA-2oz8A:
undetectable		 1nbhA-2oz8A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 2oz8 MLL7089 PROTEIN
(Mesorhizobium
japonicum) 		3 / 3 ARG A  17
ASP A 194
ASN A 246
 None
 0.83A 1nbhD-2oz8A:
undetectable		 1nbhD-2oz8A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_1
(POL POLYPROTEIN)		 2oz8 MLL7089 PROTEIN
(Mesorhizobium
japonicum) 		4 / 8 ASP A 217
ILE A 193
ILE A 211
PRO A 224
 None
 0.68A 1sh9A-2oz8A:
undetectable		 1sh9A-2oz8A:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_A_ACTA4901_0
(PYRANOSE OXIDASE)		 2oz8 MLL7089 PROTEIN
(Mesorhizobium
japonicum) 		4 / 6 PHE A 297
PHE A  13
HIS A 323
ASN A 320
 None
 1.04A 1tt0A-2oz8A:
0.0		 1tt0A-2oz8A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_B_ACTB3901_0
(PYRANOSE OXIDASE)		 2oz8 MLL7089 PROTEIN
(Mesorhizobium
japonicum) 		4 / 6 PHE A 297
PHE A  13
HIS A 323
ASN A 320
 None
 1.02A 1tt0B-2oz8A:
0.0		 1tt0B-2oz8A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_C_ACTC6901_0
(PYRANOSE OXIDASE)		 2oz8 MLL7089 PROTEIN
(Mesorhizobium
japonicum) 		4 / 6 PHE A 297
PHE A  13
HIS A 323
ASN A 320
 None
 1.06A 1tt0C-2oz8A:
0.0		 1tt0C-2oz8A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_D_ACTD5901_0
(PYRANOSE OXIDASE)		 2oz8 MLL7089 PROTEIN
(Mesorhizobium
japonicum) 		4 / 6 PHE A 297
PHE A  13
HIS A 323
ASN A 320
 None
 1.05A 1tt0D-2oz8A:
0.0		 1tt0D-2oz8A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_C_DVAC6_0
(GRAMICIDIN D)		 2oz8 MLL7089 PROTEIN
(Mesorhizobium
japonicum) 		3 / 3 ALA A 204
VAL A 209
TRP A 242
 None
 0.72A 1w5uC-2oz8A:
undetectable
1w5uD-2oz8A:
undetectable		 1w5uC-2oz8A:
4.78
1w5uD-2oz8A:
4.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_0
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2oz8 MLL7089 PROTEIN
(Mesorhizobium
japonicum) 		5 / 12 SER A 292
PHE A  52
LEU A 251
ASP A 223
GLU A 222
 None
 1.33A 3aocC-2oz8A:
undetectable		 3aocC-2oz8A:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GGU_B_017B201_2
(PROTEASE)		 2oz8 MLL7089 PROTEIN
(Mesorhizobium
japonicum) 		5 / 9 LEU A 219
ASP A 223
ASP A 194
GLY A 294
ILE A 293
 None
 0.99A 3gguB-2oz8A:
undetectable		 3gguB-2oz8A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_1
(HIV-1 PROTEASE)		 2oz8 MLL7089 PROTEIN
(Mesorhizobium
japonicum) 		5 / 12 LEU A 219
ASP A 223
ASP A 194
GLY A 294
ILE A 293
 None
 0.86A 3k4vA-2oz8A:
undetectable		 3k4vA-2oz8A:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_C_DVAC6_0
(GRAMICIDIN D)		 2oz8 MLL7089 PROTEIN
(Mesorhizobium
japonicum) 		3 / 3 ALA A 204
VAL A 209
TRP A 242
 None
 0.75A 3l8lC-2oz8A:
undetectable
3l8lD-2oz8A:
undetectable		 3l8lC-2oz8A:
4.78
3l8lD-2oz8A:
4.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_B_ACTB901_0
(PYRANOSE 2-OXIDASE)		 2oz8 MLL7089 PROTEIN
(Mesorhizobium
japonicum) 		4 / 6 PHE A 297
PHE A  13
HIS A 323
ASN A 320
 None
 1.08A 3lskB-2oz8A:
undetectable		 3lskB-2oz8A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_D_ACTD901_0
(PYRANOSE 2-OXIDASE)		 2oz8 MLL7089 PROTEIN
(Mesorhizobium
japonicum) 		4 / 6 PHE A 297
PHE A  13
HIS A 323
ASN A 320
 None
 1.18A 3lskD-2oz8A:
undetectable		 3lskD-2oz8A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_1
(PROTEASE)		 2oz8 MLL7089 PROTEIN
(Mesorhizobium
japonicum) 		5 / 12 LEU A 219
ASP A 223
ASP A 194
GLY A 294
ILE A 293
 None
 0.86A 3ndtA-2oz8A:
undetectable		 3ndtA-2oz8A:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PS9_A_SAMA670_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 2oz8 MLL7089 PROTEIN
(Mesorhizobium
japonicum) 		5 / 12 GLU A 222
ASN A 269
PHE A 140
ASP A 174
ILE A 193
 None
None
SO4  A 389 (-4.7A)
None
None
 1.26A 3ps9A-2oz8A:
undetectable		 3ps9A-2oz8A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_A_ZMRA1002_2
(NEURAMINIDASE)		 2oz8 MLL7089 PROTEIN
(Mesorhizobium
japonicum) 		4 / 5 ARG A  15
ARG A 364
ILE A  19
ARG A  17
 None
 1.23A 3ticA-2oz8A:
undetectable		 3ticA-2oz8A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VXI_A_ASCA502_0
(DYP)		 2oz8 MLL7089 PROTEIN
(Mesorhizobium
japonicum) 		4 / 5 ALA A 338
ARG A 341
PRO A 119
HIS A 303
 None
 1.19A 3vxiA-2oz8A:
0.0		 3vxiA-2oz8A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_B_SAMB301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 2oz8 MLL7089 PROTEIN
(Mesorhizobium
japonicum) 		5 / 12 ALA A  78
GLY A  44
LEU A 346
LEU A  45
ALA A 112
 None
 1.13A 4lg1B-2oz8A:
undetectable		 4lg1B-2oz8A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA303_1
(CHITOSANASE)		 2oz8 MLL7089 PROTEIN
(Mesorhizobium
japonicum) 		4 / 5 ASP A 217
HIS A 216
GLY A 188
ALA A 187
 None
 0.97A 5hwaA-2oz8A:
undetectable		 5hwaA-2oz8A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 2oz8 MLL7089 PROTEIN
(Mesorhizobium
japonicum) 		5 / 12 PHE A 162
ALA A 336
TYR A 316
ALA A 133
GLY A 334
 None
 1.27A 5tzoC-2oz8A:
undetectable		 5tzoC-2oz8A:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7P_A_SAMA501_0
(OXAC)		 2oz8 MLL7089 PROTEIN
(Mesorhizobium
japonicum) 		5 / 12 GLU A 115
GLY A  41
SER A  40
LEU A   3
ASP A 110
 None
 1.12A 5w7pA-2oz8A:
undetectable		 5w7pA-2oz8A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2oz8 MLL7089 PROTEIN
(Mesorhizobium
japonicum) 		4 / 8 HIS A  67
PHE A  65
SER A  72
LEU A  36
 None
 1.04A 5y2tB-2oz8A:
undetectable		 5y2tB-2oz8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 2oz8 MLL7089 PROTEIN
(Mesorhizobium
japonicum) 		3 / 3 ASP A  16
ARG A  17
ASP A 322
 None
 0.85A 5zvgA-2oz8A:
undetectable		 5zvgA-2oz8A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_0
(HIV-1 PROTEASE)		 2oz8 MLL7089 PROTEIN
(Mesorhizobium
japonicum) 		5 / 12 LEU A 219
ASP A 223
ASP A 194
GLY A 294
ILE A 293
 None
 0.96A 6dilA-2oz8A:
undetectable		 6dilA-2oz8A:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_C_GMJC301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 2oz8 MLL7089 PROTEIN
(Mesorhizobium
japonicum) 		4 / 6 LEU A 268
TYR A 134
ASP A 194
GLU A 222
 None
 1.48A 6djzC-2oz8A:
undetectable		 6djzC-2oz8A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_2
(SIALIDASE)		 2oz8 MLL7089 PROTEIN
(Mesorhizobium
japonicum) 		4 / 6 ASP A  57
GLN A  12
ASN A  30
LEU A 367
 None
 1.27A 6ekuA-2oz8A:
undetectable		 6ekuA-2oz8A:
19.73