SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ozf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA2_0
(FERROCHELATASE)		 2ozf EZRIN-RADIXIN-MOESIN
-BINDING
PHOSPHOPROTEIN 50
(Homo
sapiens) 		4 / 8 LEU A 168
ARG A 198
SER A 191
VAL A 231
 None
 1.02A 2qd2A-2ozfA:
undetectable		 2qd2A-2ozfA:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2ozf EZRIN-RADIXIN-MOESIN
-BINDING
PHOSPHOPROTEIN 50
(Homo
sapiens) 		4 / 7 LEU A 168
ARG A 198
SER A 191
VAL A 231
 None
 0.93A 4klrA-2ozfA:
undetectable		 4klrA-2ozfA:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQY_A_BEZA401_0
(THIOREDOXIN)		 2ozf EZRIN-RADIXIN-MOESIN
-BINDING
PHOSPHOPROTEIN 50
(Homo
sapiens) 		4 / 8 ILE A 199
VAL A 230
SER A 191
CYH A 155
 None
 1.14A 5dqyA-2ozfA:
undetectable		 5dqyA-2ozfA:
19.81