SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ozj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZE3_A_TPFA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	2ozj	CUPIN 2, CONSERVED BARREL (Desulfitobacteri um hafniense)	4 / 7	TYR A 61 ILE A 63 PHE A 44 GLY A 97	None	0.81A	4ze3A-2ozjA: undetectable	4ze3A-2ozjA: 12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ESE_A_TPFA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	2ozj	CUPIN 2, CONSERVED BARREL (Desulfitobacteri um hafniense)	4 / 8	TYR A 61 ILE A 63 PHE A 44 GLY A 97	None	0.90A	5eseA-2ozjA: undetectable	5eseA-2ozjA: 12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ESJ_A_TPFA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	2ozj	CUPIN 2, CONSERVED BARREL (Desulfitobacteri um hafniense)	4 / 8	TYR A 61 ILE A 63 PHE A 44 GLY A 97	None	0.85A	5esjA-2ozjA: undetectable	5esjA-2ozjA: 12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ESM_A_TPFA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	2ozj	CUPIN 2, CONSERVED BARREL (Desulfitobacteri um hafniense)	4 / 7	TYR A 61 ILE A 63 PHE A 44 GLY A 97	None	0.93A	5esmA-2ozjA: undetectable	5esmA-2ozjA: 12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6ECE_C_DVAC3010_0 (VLM2 DODECADEPSIPEPTIDE)	2ozj	CUPIN 2, CONSERVED BARREL (Desulfitobacteri um hafniense)	3 / 3	ALA A 30 PHE A 42 GLN A 105	None	0.65A	6eceA-2ozjA: undetectable	6eceA-2ozjA: 18.12

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4ZE3_A_TPFA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","2ozj","CUPIN 2, CONSERVED BARREL","Desulfitobacterium hafniense",4,"TYR A  61;ILE A  63;PHE A  44;GLY A  97","None","0.81A","4ze3A-2ozjA:undetectable","4ze3A-2ozjA:12.98"],["5ESE_A_TPFA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","2ozj","CUPIN 2, CONSERVED BARREL","Desulfitobacterium hafniense",4,"TYR A  61;ILE A  63;PHE A  44;GLY A  97","None","0.90A","5eseA-2ozjA:undetectable","5eseA-2ozjA:12.98"],["5ESJ_A_TPFA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","2ozj","CUPIN 2, CONSERVED BARREL","Desulfitobacterium hafniense",4,"TYR A  61;ILE A  63;PHE A  44;GLY A  97","None","0.85A","5esjA-2ozjA:undetectable","5esjA-2ozjA:12.98"],["5ESM_A_TPFA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","2ozj","CUPIN 2, CONSERVED BARREL","Desulfitobacterium hafniense",4,"TYR A  61;ILE A  63;PHE A  44;GLY A  97","None","0.93A","5esmA-2ozjA:undetectable","5esmA-2ozjA:12.98"],["6ECE_C_DVAC3010_0","VLM2;DODECADEPSIPEPTIDE","2ozj","CUPIN 2, CONSERVED BARREL","Desulfitobacterium hafniense",3,"ALA A  30;PHE A  42;GLN A 105","None","0.65A","6eceA-2ozjA:undetectable","6eceA-2ozjA:18.12"]]