SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ozu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_2
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 2ozu HISTONE
ACETYLTRANSFERASE
MYST3
(Homo
sapiens) 		4 / 7 ALA A 567
PHE A 579
VAL A 581
VAL A 617
 None
 0.85A 1epbA-2ozuA:
undetectable		 1epbA-2ozuA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKO_A_EFZA999_1
(HIV-1 RT, A-CHAIN)		 2ozu HISTONE
ACETYLTRANSFERASE
MYST3
(Homo
sapiens) 		5 / 10 LEU A 593
VAL A 610
VAL A 581
TYR A 589
GLY A 583
 None
 1.46A 1fkoA-2ozuA:
undetectable		 1fkoA-2ozuA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PJ7_A_FFOA2887_1
(N,N-DIMETHYLGLYCINE
OXIDASE)		 2ozu HISTONE
ACETYLTRANSFERASE
MYST3
(Homo
sapiens) 		3 / 3 ASP A 609
THR A 605
GLU A 680
 None
ALY  A 604 ( 3.9A)
None
 0.44A 1pj7A-2ozuA:
undetectable		 1pj7A-2ozuA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_2
(ANDROGEN RECEPTOR)		 2ozu HISTONE
ACETYLTRANSFERASE
MYST3
(Homo
sapiens) 		4 / 6 LEU A 614
LEU A 662
LEU A 669
ILE A 647
 None
None
None
ACO  A 850 (-4.6A)
 1.02A 1z95A-2ozuA:
undetectable		 1z95A-2ozuA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P16_A_GG2A298_2
(COAGULATION FACTOR X
(EC 3.4.21.6)
(STUART FACTOR)
(STUART-PROWER
FACTOR))		 2ozu HISTONE
ACETYLTRANSFERASE
MYST3
(Homo
sapiens) 		3 / 3 ARG A 533
GLU A 530
GLN A 529
 None
 1.10A 2p16A-2ozuA:
undetectable		 2p16A-2ozuA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1161_1
(ALLERGEN ARG R 1)		 2ozu HISTONE
ACETYLTRANSFERASE
MYST3
(Homo
sapiens) 		4 / 5 VAL A 617
TYR A 616
ASP A 582
SER A 586
 None
 1.31A 2x45A-2ozuA:
undetectable		 2x45A-2ozuA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1161_1
(ALLERGEN ARG R 1)		 2ozu HISTONE
ACETYLTRANSFERASE
MYST3
(Homo
sapiens) 		4 / 5 VAL A 617
TYR A 616
ASP A 582
SER A 586
 None
 1.21A 2x45C-2ozuA:
undetectable		 2x45C-2ozuA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_G_CPFG1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 2ozu HISTONE
ACETYLTRANSFERASE
MYST3
(Homo
sapiens) 		3 / 3 ARG A 660
GLY A 659
SER A 684
 None
ACO  A 850 (-3.4A)
ACO  A 850 (-2.8A)
 0.59A 2xctB-2ozuA:
undetectable		 2xctB-2ozuA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2ozu HISTONE
ACETYLTRANSFERASE
MYST3
(Homo
sapiens) 		3 / 3 PHE A 563
CYH A 626
HIS A 564
 None
 0.62A 3u9fF-2ozuA:
undetectable		 3u9fF-2ozuA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2ozu HISTONE
ACETYLTRANSFERASE
MYST3
(Homo
sapiens) 		3 / 3 PHE A 563
CYH A 626
HIS A 564
 None
 0.60A 3u9fG-2ozuA:
undetectable		 3u9fG-2ozuA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2ozu HISTONE
ACETYLTRANSFERASE
MYST3
(Homo
sapiens) 		3 / 3 PHE A 563
CYH A 626
HIS A 564
 None
 0.65A 3u9fL-2ozuA:
undetectable		 3u9fL-2ozuA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_R_CLMR221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2ozu HISTONE
ACETYLTRANSFERASE
MYST3
(Homo
sapiens) 		3 / 3 PHE A 563
CYH A 626
HIS A 564
 None
 0.63A 3u9fS-2ozuA:
undetectable		 3u9fS-2ozuA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2ozu HISTONE
ACETYLTRANSFERASE
MYST3
(Homo
sapiens) 		4 / 8 PRO A 528
LEU A 595
VAL A 610
TYR A 608
 None
 0.98A 4pwdA-2ozuA:
undetectable		 4pwdA-2ozuA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_E_CHDE401_0
(BILE SALT HYDROLASE)		 2ozu HISTONE
ACETYLTRANSFERASE
MYST3
(Homo
sapiens) 		4 / 8 TYR A 653
ILE A 649
LEU A 618
LEU A 544
 None
ACO  A 850 (-3.6A)
None
None
 0.87A 5y7pE-2ozuA:
undetectable		 5y7pE-2ozuA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA811_0
(GEPHYRIN)		 2ozu HISTONE
ACETYLTRANSFERASE
MYST3
(Homo
sapiens) 		3 / 3 LEU A 669
LEU A 774
ARG A 672
 None
 0.69A 6fgcA-2ozuA:
undetectable		 6fgcA-2ozuA:
18.18