SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ozz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ6_A_CAMA502_0
(CYTOCHROME P450-CAM)		 2ozz HYPOTHETICAL PROTEIN
YHFZ
(Shigella
flexneri) 		4 / 5 PHE A  43
TYR A  45
LEU A  30
VAL A 207
 None
 1.47A 1dz6A-2ozzA:
undetectable		 1dz6A-2ozzA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ6_B_CAMB502_0
(CYTOCHROME P450-CAM)		 2ozz HYPOTHETICAL PROTEIN
YHFZ
(Shigella
flexneri) 		4 / 5 PHE A  43
TYR A  45
VAL A  67
VAL A 207
 None
 1.20A 1dz6B-2ozzA:
undetectable		 1dz6B-2ozzA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ6_B_CAMB502_0
(CYTOCHROME P450-CAM)		 2ozz HYPOTHETICAL PROTEIN
YHFZ
(Shigella
flexneri) 		4 / 5 PHE A  43
TYR A  45
VAL A 190
VAL A 206
 None
 1.26A 1dz6B-2ozzA:
undetectable		 1dz6B-2ozzA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WM3_A_NFLA1301_1
(NMRA-LIKE FAMILY
DOMAIN CONTAINING
PROTEIN 1)		 2ozz HYPOTHETICAL PROTEIN
YHFZ
(Shigella
flexneri) 		4 / 6 LEU A 139
ARG A 111
LEU A 145
ASP A 152
 None
 0.99A 2wm3A-2ozzA:
undetectable		 2wm3A-2ozzA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_C_486C4_1
(GLUCOCORTICOID
RECEPTOR)		 2ozz HYPOTHETICAL PROTEIN
YHFZ
(Shigella
flexneri) 		5 / 12 LEU A  34
GLY A  29
GLN A 216
VAL A 219
LEU A 213
 None
 1.36A 3h52C-2ozzA:
undetectable		 3h52C-2ozzA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_C_VK3C202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 2ozz HYPOTHETICAL PROTEIN
YHFZ
(Shigella
flexneri) 		4 / 7 ARG A  54
TYR A  27
TYR A  93
TYR A 141
 SO4  A 229 (-2.6A)
None
None
None
 1.27A 4f8yC-2ozzA:
undetectable
4f8yD-2ozzA:
undetectable		 4f8yC-2ozzA:
21.49
4f8yD-2ozzA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 2ozz HYPOTHETICAL PROTEIN
YHFZ
(Shigella
flexneri) 		3 / 3 SER A  75
ASP A 138
ASP A 120
 None
 0.79A 4uckA-2ozzA:
undetectable		 4uckA-2ozzA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2ozz HYPOTHETICAL PROTEIN
YHFZ
(Shigella
flexneri) 		3 / 3 GLY A  29
VAL A  67
MET A  19
 None
 0.63A 5ycpA-2ozzA:
undetectable		 5ycpA-2ozzA:
17.54