SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2p0g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2p0g SELENOPROTEIN
W-RELATED PROTEIN
(Vibrio
cholerae) 		3 / 3 GLU A  49
TYR A   9
PHE A  51
 None
 0.73A 1eqbB-2p0gA:
undetectable		 1eqbB-2p0gA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2p0g SELENOPROTEIN
W-RELATED PROTEIN
(Vibrio
cholerae) 		3 / 3 GLU A  49
TYR A   9
PHE A  51
 None
 0.72A 1eqbA-2p0gA:
undetectable		 1eqbA-2p0gA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2p0g SELENOPROTEIN
W-RELATED PROTEIN
(Vibrio
cholerae) 		3 / 3 GLU A  49
TYR A   9
PHE A  51
 None
 0.72A 1eqbD-2p0gA:
undetectable		 1eqbD-2p0gA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2p0g SELENOPROTEIN
W-RELATED PROTEIN
(Vibrio
cholerae) 		3 / 3 GLU A  49
TYR A   9
PHE A  51
 None
 0.72A 1eqbC-2p0gA:
undetectable		 1eqbC-2p0gA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI7_B_ID2B2_0
(THYMIDINE KINASE)		 2p0g SELENOPROTEIN
W-RELATED PROTEIN
(Vibrio
cholerae) 		5 / 12 HIS A  41
ILE A   6
ILE A  50
ALA A  21
GLU A   7
 None
 1.36A 1ki7B-2p0gA:
undetectable		 1ki7B-2p0gA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRM_A_VD3A502_1
(VITAMIN D(3)
25-HYDROXYLASE)		 2p0g SELENOPROTEIN
W-RELATED PROTEIN
(Vibrio
cholerae) 		5 / 12 ILE A  57
LEU A  79
ILE A  80
ILE A   8
LEU A  27
 None
 0.99A 3vrmA-2p0gA:
undetectable		 3vrmA-2p0gA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_A_ACTA502_0
(RNA-DEPENDENT RNA
POLYMERASE)		 2p0g SELENOPROTEIN
W-RELATED PROTEIN
(Vibrio
cholerae) 		4 / 5 LYS A  73
LEU A  72
GLU A  26
LEU A  23
 None
 1.32A 4k4yA-2p0gA:
undetectable		 4k4yA-2p0gA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_I_ACTI503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 2p0g SELENOPROTEIN
W-RELATED PROTEIN
(Vibrio
cholerae) 		4 / 5 LYS A  73
LEU A  72
GLU A  26
LEU A  23
 None
 1.31A 4k4yI-2p0gA:
undetectable		 4k4yI-2p0gA:
12.71