SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2p0o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2p0o HYPOTHETICAL PROTEIN
DUF871
(Enterococcus
faecalis) 		4 / 8 GLY A  30
ALA A  56
THR A  91
ILE A  31
 None
 0.82A 1c9sU-2p0oA:
undetectable
1c9sV-2p0oA:
undetectable		 1c9sU-2p0oA:
12.84
1c9sV-2p0oA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FIQ_C_SALC1335_1
(XANTHINE OXIDASE)		 2p0o HYPOTHETICAL PROTEIN
DUF871
(Enterococcus
faecalis) 		5 / 8 LEU A  88
PHE A  77
VAL A  65
LEU A  35
ALA A  75
 None
 1.42A 1fiqC-2p0oA:
undetectable		 1fiqC-2p0oA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2p0o HYPOTHETICAL PROTEIN
DUF871
(Enterococcus
faecalis) 		4 / 7 GLY A  30
ALA A  56
THR A  91
ILE A  31
 None
 0.82A 1gtnA-2p0oA:
undetectable
1gtnK-2p0oA:
undetectable		 1gtnA-2p0oA:
12.84
1gtnK-2p0oA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2p0o HYPOTHETICAL PROTEIN
DUF871
(Enterococcus
faecalis) 		4 / 8 GLY A  30
ALA A  56
THR A  91
ILE A  31
 None
 0.81A 1gtnA-2p0oA:
undetectable
1gtnB-2p0oA:
undetectable		 1gtnA-2p0oA:
12.84
1gtnB-2p0oA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2p0o HYPOTHETICAL PROTEIN
DUF871
(Enterococcus
faecalis) 		4 / 8 GLY A  30
ALA A  56
THR A  91
ILE A  31
 None
 0.83A 1gtnE-2p0oA:
undetectable
1gtnF-2p0oA:
undetectable		 1gtnE-2p0oA:
12.84
1gtnF-2p0oA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2p0o HYPOTHETICAL PROTEIN
DUF871
(Enterococcus
faecalis) 		4 / 8 GLY A  30
ALA A  56
THR A  91
ILE A  31
 None
 0.82A 1gtnP-2p0oA:
undetectable
1gtnQ-2p0oA:
undetectable		 1gtnP-2p0oA:
12.84
1gtnQ-2p0oA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMT_A_H4BA1426_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 2p0o HYPOTHETICAL PROTEIN
DUF871
(Enterococcus
faecalis) 		5 / 11 VAL A 302
LEU A 256
LEU A 354
LEU A 241
THR A 333
 None
 1.15A 1mmtA-2p0oA:
undetectable		 1mmtA-2p0oA:
25.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2p0o HYPOTHETICAL PROTEIN
DUF871
(Enterococcus
faecalis) 		3 / 3 GLU A 159
GLU A 166
LEU A 122
 None
 0.71A 1v8bA-2p0oA:
undetectable		 1v8bA-2p0oA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2p0o HYPOTHETICAL PROTEIN
DUF871
(Enterococcus
faecalis) 		3 / 3 LEU A  85
PRO A  84
LEU A  88
 None
 0.55A 3hcrA-2p0oA:
undetectable		 3hcrA-2p0oA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_A_C2FA314_0
(UNCHARACTERIZED
PROTEIN)		 2p0o HYPOTHETICAL PROTEIN
DUF871
(Enterococcus
faecalis) 		5 / 12 LEU A  72
GLY A 114
LEU A 115
LEU A  85
ILE A  86
 None
 1.13A 3ijdA-2p0oA:
9.0		 3ijdA-2p0oA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WZE_A_BAXA1201_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 2p0o HYPOTHETICAL PROTEIN
DUF871
(Enterococcus
faecalis) 		4 / 8 VAL A  90
LEU A  88
ILE A  86
PHE A  77
 None
 0.67A 3wzeA-2p0oA:
undetectable		 3wzeA-2p0oA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HDL_A_DXCA75_0
(PPCA)		 2p0o HYPOTHETICAL PROTEIN
DUF871
(Enterococcus
faecalis) 		5 / 8 ILE A 101
ILE A 113
PHE A 135
LYS A 165
GLY A 168
 None
 1.50A 4hdlA-2p0oA:
undetectable		 4hdlA-2p0oA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QRC_A_0LIA802_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 2p0o HYPOTHETICAL PROTEIN
DUF871
(Enterococcus
faecalis) 		4 / 8 LEU A  88
VAL A  90
ILE A  67
ALA A  75
 None
 0.85A 4qrcA-2p0oA:
undetectable		 4qrcA-2p0oA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB5_A_010A609_0
(HNL ISOENZYME 5)		 2p0o HYPOTHETICAL PROTEIN
DUF871
(Enterococcus
faecalis) 		5 / 11 ALA A  75
ALA A  71
LEU A  72
LEU A  85
VAL A  65
 None
 1.09A 5eb5A-2p0oA:
undetectable		 5eb5A-2p0oA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EQB_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2p0o HYPOTHETICAL PROTEIN
DUF871
(Enterococcus
faecalis) 		6 / 12 GLY A 358
PHE A  28
ILE A   4
TYR A  19
PHE A 231
GLY A   3
 None
 1.40A 5eqbA-2p0oA:
undetectable		 5eqbA-2p0oA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2p0o HYPOTHETICAL PROTEIN
DUF871
(Enterococcus
faecalis) 		5 / 12 GLY A 358
PHE A  28
ILE A   4
TYR A  19
PHE A 231
 None
 1.19A 5eskA-2p0oA:
undetectable		 5eskA-2p0oA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2p0o HYPOTHETICAL PROTEIN
DUF871
(Enterococcus
faecalis) 		5 / 12 GLY A 358
PHE A  28
ILE A   4
TYR A  19
PHE A 231
 None
 1.20A 5eslA-2p0oA:
undetectable		 5eslA-2p0oA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2S_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 2p0o HYPOTHETICAL PROTEIN
DUF871
(Enterococcus
faecalis) 		4 / 8 PRO A 298
LYS A 325
THR A 331
THR A 301
 None
 1.14A 5x2sI-2p0oA:
undetectable
5x2sJ-2p0oA:
undetectable
5x2sK-2p0oA:
undetectable		 5x2sI-2p0oA:
19.09
5x2sJ-2p0oA:
19.13
5x2sK-2p0oA:
19.09