SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2p0y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_D_ADND604_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 2p0y HYPOTHETICAL PROTEIN
LP_0780
(Lactobacillus
plantarum) 		4 / 5 GLU A 235
THR A 236
HIS A 244
HIS A 251
 None
 1.49A 1d4fD-2p0yA:
4.9		 1d4fD-2p0yA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 2p0y HYPOTHETICAL PROTEIN
LP_0780
(Lactobacillus
plantarum) 		5 / 10 VAL A 117
VAL A  40
ASN A 122
ILE A  13
LEU A  71
 None
 1.19A 1fe2A-2p0yA:
undetectable		 1fe2A-2p0yA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_K_BEZK4387_0
(CES1 PROTEIN)		 2p0y HYPOTHETICAL PROTEIN
LP_0780
(Lactobacillus
plantarum) 		3 / 3 TRP A 167
LEU A 138
LYS A 176
 None
 1.02A 1yajK-2p0yA:
3.1		 1yajK-2p0yA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1291_1
(FICOLIN-2)		 2p0y HYPOTHETICAL PROTEIN
LP_0780
(Lactobacillus
plantarum) 		4 / 6 SER A 285
SER A 240
ASP A 243
ASP A 287
 None
 1.24A 2j2pE-2p0yA:
undetectable
2j2pF-2p0yA:
undetectable		 2j2pE-2p0yA:
22.53
2j2pF-2p0yA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD37_0
(GCN4 LEUCINE ZIPPER)		 2p0y HYPOTHETICAL PROTEIN
LP_0780
(Lactobacillus
plantarum) 		3 / 3 LYS A  10
ARG A 333
VAL A 326
 None
 1.04A 2r2vC-2p0yA:
undetectable
2r2vD-2p0yA:
undetectable		 2r2vC-2p0yA:
9.34
2r2vD-2p0yA:
9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X7H_B_PFNB1374_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 2p0y HYPOTHETICAL PROTEIN
LP_0780
(Lactobacillus
plantarum) 		4 / 4 TYR A 225
LEU A 194
LEU A 248
HIS A 244
 None
 1.37A 2x7hB-2p0yA:
4.1		 2x7hB-2p0yA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P)		 2p0y HYPOTHETICAL PROTEIN
LP_0780
(Lactobacillus
plantarum) 		4 / 8 VAL A  67
ILE A 226
VAL A 193
GLY A  17
 None
 0.84A 3hjoB-2p0yA:
undetectable		 3hjoB-2p0yA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MAF_A_XINA403_2
(MATERNAL EMBRYONIC
LEUCINE ZIPPER
KINASE)		 2p0y HYPOTHETICAL PROTEIN
LP_0780
(Lactobacillus
plantarum) 		4 / 5 LEU A 199
CYH A 296
LEU A 291
ASP A 243
 None
 1.36A 5mafA-2p0yA:
undetectable		 5mafA-2p0yA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_B_ADNB503_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 2p0y HYPOTHETICAL PROTEIN
LP_0780
(Lactobacillus
plantarum) 		4 / 5 LEU A 261
VAL A 224
GLU A 222
LEU A 325
 None
 0.81A 5xooB-2p0yA:
undetectable		 5xooB-2p0yA:
11.78