SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2p19'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_A_ACTA141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 2p19 TRANSCRIPTIONAL
REGULATOR
(Corynebacterium
glutamicum) 		3 / 3 VAL A  64
ASP A  63
GLU A  68
 None
 0.72A 2qeuA-2p19A:
undetectable		 2qeuA-2p19A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_C_ACTC141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 2p19 TRANSCRIPTIONAL
REGULATOR
(Corynebacterium
glutamicum) 		3 / 3 VAL A  64
ASP A  63
GLU A  68
 None
 0.72A 2qeuC-2p19A:
undetectable		 2qeuC-2p19A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGO_A_PCFA1213_1
(WNT INHIBITORY
FACTOR 1)		 2p19 TRANSCRIPTIONAL
REGULATOR
(Corynebacterium
glutamicum) 		4 / 6 LEU A  78
ILE A 128
PRO A  58
VAL A  50
 None
 0.90A 2ygoA-2p19A:
undetectable		 2ygoA-2p19A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJ8_C_SPMC500_1
(DIAMINE
ACETYLTRANSFERASE 1)		 2p19 TRANSCRIPTIONAL
REGULATOR
(Corynebacterium
glutamicum) 		4 / 6 ASP A  76
LEU A  78
LEU A  53
HIS A 133
 None
 1.16A 3bj8C-2p19A:
undetectable
3bj8D-2p19A:
undetectable		 3bj8C-2p19A:
19.54
3bj8D-2p19A:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA506_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2p19 TRANSCRIPTIONAL
REGULATOR
(Corynebacterium
glutamicum) 		4 / 4 PRO A  49
LEU A  42
ILE A  52
ARG A  40
 None
 1.35A 4f4dA-2p19A:
undetectable		 4f4dA-2p19A:
19.67