SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2p1a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EFJ_A_37TA502_1
(3,7-DIMETHYLXANTHINE
METHYLTRANSFERASE)		 2p1a HYPOTHETICAL PROTEIN
(Bacillus
cereus) 		5 / 12 TYR A 111
HIS A 128
ILE A  50
ILE A 125
ILE A  57
 None
 1.25A 2efjA-2p1aA:
undetectable		 2efjA-2p1aA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_E_GCSE710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 2p1a HYPOTHETICAL PROTEIN
(Bacillus
cereus) 		4 / 8 HIS A 128
TRP A 112
ASP A  54
ILE A  57
 None
 1.03A 2xadA-2p1aA:
undetectable		 2xadA-2p1aA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_F_GCSF710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 2p1a HYPOTHETICAL PROTEIN
(Bacillus
cereus) 		4 / 8 HIS A 128
TRP A 112
ASP A  54
ILE A  57
 None
 1.04A 2xadB-2p1aA:
undetectable		 2xadB-2p1aA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_G_GCSG710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 2p1a HYPOTHETICAL PROTEIN
(Bacillus
cereus) 		4 / 8 HIS A 128
TRP A 112
ASP A  54
ILE A  57
 None
 1.03A 2xadC-2p1aA:
undetectable		 2xadC-2p1aA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_H_GCSH710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 2p1a HYPOTHETICAL PROTEIN
(Bacillus
cereus) 		4 / 8 HIS A 128
TRP A 112
ASP A  54
ILE A  57
 None
 1.02A 2xadD-2p1aA:
undetectable		 2xadD-2p1aA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2p1a HYPOTHETICAL PROTEIN
(Bacillus
cereus) 		4 / 6 GLN A   4
PHE A   2
PHE A 119
LEU A 123
 None
 1.12A 5b1bC-2p1aA:
2.7
5b1bJ-2p1aA:
undetectable		 5b1bC-2p1aA:
20.55
5b1bJ-2p1aA:
17.81