SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2p26'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_A_CCSA417_0
(ESTROGEN RECEPTOR)		 2p26 INTEGRIN BETA-2
(Homo
sapiens) 		3 / 3 GLU A  13
LYS A   7
VAL A   8
 None
 0.94A 1l2iA-2p26A:
undetectable		 1l2iA-2p26A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 2p26 INTEGRIN BETA-2
(Homo
sapiens) 		5 / 12 VAL A 358
PHE A 404
ILE A 406
LEU A  76
LEU A  83
 None
 1.23A 2jn3A-2p26A:
undetectable		 2jn3A-2p26A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 2p26 INTEGRIN BETA-2
(Homo
sapiens) 		5 / 12 VAL A 358
PHE A 404
LEU A  76
VAL A 417
LEU A  83
 None
 1.16A 2jn3A-2p26A:
undetectable		 2jn3A-2p26A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2p26 INTEGRIN BETA-2
(Homo
sapiens) 		4 / 5 LEU A 471
GLN A 464
THR A 463
GLU A 470
 None
 1.35A 3n58C-2p26A:
undetectable		 3n58C-2p26A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB5_A_010A609_0
(HNL ISOENZYME 5)		 2p26 INTEGRIN BETA-2
(Homo
sapiens) 		5 / 11 ALA A  91
ALA A  63
VAL A  81
LEU A 356
VAL A 417
 None
 1.13A 5eb5A-2p26A:
undetectable		 5eb5A-2p26A:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB5_B_010B607_0
(HNL ISOENZYME 5)		 2p26 INTEGRIN BETA-2
(Homo
sapiens) 		5 / 10 ALA A  91
ALA A  63
VAL A  81
LEU A 356
VAL A 417
 None
 1.08A 5eb5B-2p26A:
undetectable		 5eb5B-2p26A:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUN_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 2p26 INTEGRIN BETA-2
(Homo
sapiens) 		6 / 9 ALA A  91
VAL A 393
ILE A 406
ASN A  94
PHE A  93
ALA A  63
 None
None
None
NAG  A 301 (-1.7A)
None
None
 1.24A 5nunA-2p26A:
undetectable		 5nunA-2p26A:
19.67