SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2p2e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX7_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 2p2e PUTATIVE FE-S
BIOSYNTHESIS PROTEIN
(Lactobacillus
salivarius) 		5 / 12 ILE A   5
PHE A  75
ILE A 116
LEU A  15
ILE A  91
 None
 1.01A 1rx7A-2p2eA:
undetectable		 1rx7A-2p2eA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BL9_A_CP6A1240_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2p2e PUTATIVE FE-S
BIOSYNTHESIS PROTEIN
(Lactobacillus
salivarius) 		5 / 12 ILE A   5
PHE A  75
SER A 115
ILE A 116
ILE A  91
 None
 1.18A 2bl9A-2p2eA:
undetectable		 2bl9A-2p2eA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BLA_A_CP6A302_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2p2e PUTATIVE FE-S
BIOSYNTHESIS PROTEIN
(Lactobacillus
salivarius) 		5 / 11 ILE A   5
PHE A  75
SER A 115
ILE A 116
ILE A  91
 None
 1.11A 2blaA-2p2eA:
undetectable		 2blaA-2p2eA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D0K_A_FOLA1161_0
(DIHYDROFOLATE
REDUCTASE)		 2p2e PUTATIVE FE-S
BIOSYNTHESIS PROTEIN
(Lactobacillus
salivarius) 		5 / 12 ILE A   5
PHE A  75
ILE A 116
LEU A  15
ILE A  91
 None
 0.86A 2d0kA-2p2eA:
undetectable		 2d0kA-2p2eA:
21.25