SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2p2m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_A_DVAA6_0
(GRAMICIDIN A)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		3 / 3 ALA A 434
VAL A 409
TRP A 399
 None
 0.86A 1bdwA-2p2mA:
undetectable
1bdwB-2p2mA:
undetectable		 1bdwA-2p2mA:
3.12
1bdwB-2p2mA:
3.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DWC_H_MITH1_1
(ALPHA-THROMBIN
(LARGE SUBUNIT))		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		5 / 9 TYR A 576
TRP A 598
ILE A 559
GLU A 578
GLY A 588
 None
 1.17A 1dwcH-2p2mA:
undetectable		 1dwcH-2p2mA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		5 / 11 TYR A 488
ARG A 526
ILE A  67
HIS A 276
PHE A 484
 None
PRX  A 998 (-3.9A)
None
None
None
 1.34A 1fkfA-2p2mA:
undetectable		 1fkfA-2p2mA:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKJ_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		5 / 11 TYR A 488
ARG A 526
ILE A  67
HIS A 276
PHE A 484
 None
PRX  A 998 (-3.9A)
None
None
None
 1.35A 1fkjA-2p2mA:
undetectable		 1fkjA-2p2mA:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G60_A_SAMA500_0
(ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		5 / 12 ASN A 352
PRO A 358
GLY A 384
SER A 385
TYR A 355
 None
 1.36A 1g60A-2p2mA:
2.3		 1g60A-2p2mA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K4T_D_TTCD990_1
(DNA TOPOISOMERASE I)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		4 / 5 GLU A 531
ARG A 515
ASP A 500
THR A 418
 None
PRX  A 998 (-4.0A)
PRX  A 998 (-2.7A)
None
 1.19A 1k4tA-2p2mA:
undetectable		 1k4tA-2p2mA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_B_NOVB444_1
(DNA GYRASE SUBUNIT B)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		5 / 12 ASN A  76
GLU A 251
ILE A 155
ASP A 126
ALA A  78
 None
 1.15A 1kijB-2p2mA:
undetectable		 1kijB-2p2mA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RR8_A_TTCA100_1
(DNA TOPOISOMERASE I)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		4 / 5 GLU A 531
ARG A 515
ASP A 500
THR A 418
 None
PRX  A 998 (-4.0A)
PRX  A 998 (-2.7A)
None
 1.24A 1rr8C-2p2mA:
undetectable		 1rr8C-2p2mA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RRJ_B_TTCB990_1
(DNA TOPOISOMERASE I)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		4 / 5 GLU A 531
ARG A 515
ASP A 500
THR A 418
 None
PRX  A 998 (-4.0A)
PRX  A 998 (-2.7A)
None
 1.21A 1rrjA-2p2mA:
undetectable		 1rrjA-2p2mA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_A_CTXA1_1
(CES1 PROTEIN)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		5 / 12 ALA A 286
GLY A 280
GLY A 279
LEU A  46
LEU A  75
 None
 0.83A 1ya4A-2p2mA:
3.0		 1ya4A-2p2mA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1502_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		4 / 5 PRO A 358
GLY A 556
ASN A 521
GLY A 524
 None
None
PRX  A 998 ( 4.9A)
None
 1.10A 1zlqA-2p2mA:
undetectable		 1zlqA-2p2mA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		5 / 10 THR A 487
THR A 416
LEU A 477
VAL A 274
GLY A 273
 None
PRX  A 998 (-3.7A)
None
None
None
 1.15A 2cp4A-2p2mA:
undetectable		 2cp4A-2p2mA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		5 / 10 TYR A 488
THR A 416
LEU A 477
VAL A 274
GLY A 273
 None
PRX  A 998 (-3.7A)
None
None
None
 1.12A 2cp4A-2p2mA:
undetectable		 2cp4A-2p2mA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		4 / 7 TYR A 488
THR A 416
LEU A 477
VAL A 274
 None
PRX  A 998 (-3.7A)
None
None
 1.07A 2cppA-2p2mA:
undetectable		 2cppA-2p2mA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FKE_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		5 / 11 TYR A 488
ARG A 526
ILE A  67
HIS A 276
PHE A 484
 None
PRX  A 998 (-3.9A)
None
None
None
 1.34A 2fkeA-2p2mA:
undetectable		 2fkeA-2p2mA:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1121_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		4 / 5 SER A 180
VAL A 183
SER A 160
VAL A 134
 None
 1.03A 2j9cA-2p2mA:
undetectable
2j9cB-2p2mA:
undetectable
2j9cC-2p2mA:
2.6		 2j9cA-2p2mA:
10.97
2j9cB-2p2mA:
10.97
2j9cC-2p2mA:
10.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2P2F_A_ACTA653_0
(ACETYL-COENZYME A
SYNTHETASE)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		5 / 5 VAL A 310
THR A 311
VAL A 386
GLY A 387
TRP A 414
 None
PRX  A 998 (-4.3A)
None
PRX  A 998 (-3.4A)
PRX  A 998 (-3.4A)
 0.17A 2p2fA-2p2mA:
66.8		 2p2fA-2p2mA:
99.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2P2F_B_ACTB653_0
(ACETYL-COENZYME A
SYNTHETASE)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		4 / 4 VAL A 310
THR A 311
VAL A 386
GLY A 387
 None
PRX  A 998 (-4.3A)
None
PRX  A 998 (-3.4A)
 0.13A 2p2fB-2p2mA:
67.0		 2p2fB-2p2mA:
99.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_A_ACTA142_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		4 / 5 GLU A 188
PRO A 197
ILE A 196
GLY A 189
 None
 1.15A 2qeuA-2p2mA:
undetectable
2qeuC-2p2mA:
undetectable		 2qeuA-2p2mA:
12.52
2qeuC-2p2mA:
12.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VD0_B_D27B1200_0
(GLUTATHIONE-REQUIRIN
G PROSTAGLANDIN D
SYNTHASE)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		5 / 10 GLY A 319
ALA A  78
TYR A 295
THR A 327
LEU A 317
 None
 1.33A 2vd0B-2p2mA:
0.0		 2vd0B-2p2mA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_2
(AAC(6')-IB)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		3 / 3 TRP A  39
GLN A 445
TRP A 414
 None
None
PRX  A 998 (-3.4A)
 1.00A 2vqyA-2p2mA:
undetectable		 2vqyA-2p2mA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_A_IBPA1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		4 / 7 VAL A 386
GLY A 387
THR A 416
ARG A 526
 None
PRX  A 998 (-3.4A)
PRX  A 998 (-3.7A)
PRX  A 998 (-3.9A)
 0.34A 2wd9A-2p2mA:
41.8		 2wd9A-2p2mA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_B_IBPB1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		5 / 8 VAL A 386
GLY A 387
GLN A 415
THR A 416
ARG A 526
 None
PRX  A 998 (-3.4A)
PRX  A 998 (-3.9A)
PRX  A 998 (-3.7A)
PRX  A 998 (-3.9A)
 0.52A 2wd9B-2p2mA:
41.0		 2wd9B-2p2mA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_C_IBPC1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		6 / 10 THR A 264
VAL A 386
GLY A 387
GLN A 415
THR A 416
ARG A 526
 PRX  A 998 ( 4.9A)
None
PRX  A 998 (-3.4A)
PRX  A 998 (-3.9A)
PRX  A 998 (-3.7A)
PRX  A 998 (-3.9A)
 0.66A 2wd9C-2p2mA:
41.0		 2wd9C-2p2mA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB6_0
(GRAMICIDIN D)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		3 / 3 TRP A  97
ALA A 146
VAL A 142
 None
 0.96A 3l8lA-2p2mA:
undetectable
3l8lB-2p2mA:
undetectable		 3l8lA-2p2mA:
3.12
3l8lB-2p2mA:
4.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_A_ACTA207_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		4 / 7 LEU A 220
ASP A 187
ARG A 222
ALA A 186
 None
 1.28A 3mbgA-2p2mA:
undetectable
3mbgB-2p2mA:
undetectable		 3mbgA-2p2mA:
12.42
3mbgB-2p2mA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ0_X_DXCX75_0
(CYTOCHROME C7)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		4 / 7 ILE A  45
LYS A  56
PHE A  38
GLY A 443
 None
 1.22A 3sj0X-2p2mA:
undetectable		 3sj0X-2p2mA:
8.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_A_SALA404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		4 / 7 ALA A 558
TYR A 560
ARG A 616
ALA A 619
 None
 1.16A 3twpA-2p2mA:
undetectable		 3twpA-2p2mA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_B_SALB404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		4 / 7 ALA A 558
TYR A 560
ARG A 616
ALA A 619
 None
 1.03A 3twpB-2p2mA:
undetectable		 3twpB-2p2mA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5J_A_08HA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		4 / 7 PRO A 143
LEU A 317
LEU A 321
ILE A 108
 None
 1.05A 3u5jA-2p2mA:
undetectable		 3u5jA-2p2mA:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW7_A_VPXA2001_1
(PROTEINASE-ACTIVATED
RECEPTOR 1, LYSOZYME)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		5 / 12 LEU A  82
LEU A 259
ALA A 286
ALA A 285
TYR A 318
 None
 1.12A 3vw7A-2p2mA:
undetectable		 3vw7A-2p2mA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEO_A_ACRA1001_2
(ALPHA-GLUCOSIDASE)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		4 / 6 ILE A  67
TRP A  48
ILE A  45
TRP A  39
 None
 1.17A 3weoA-2p2mA:
undetectable		 3weoA-2p2mA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYS_A_ACTA402_0
(MCCC FAMILY PROTEIN)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		4 / 6 ASP A 517
SER A 267
ARG A 526
GLU A 417
 None
None
PRX  A 998 (-3.9A)
PRX  A 998 ( 4.8A)
 1.21A 4eysA-2p2mA:
2.6		 4eysA-2p2mA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LZR_A_LOCA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		4 / 8 LEU A 317
LEU A 321
TYR A 110
ILE A 108
 None
 0.88A 4lzrA-2p2mA:
undetectable		 4lzrA-2p2mA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_C_AERC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		4 / 6 ASP A 234
GLU A 215
VAL A 135
ALA A 136
 None
 0.95A 4nkvC-2p2mA:
undetectable		 4nkvC-2p2mA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		4 / 5 GLY A 232
ASP A 234
GLU A 215
VAL A 135
 None
 0.93A 4nkvD-2p2mA:
undetectable		 4nkvD-2p2mA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA303_1
(CHITOSANASE)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		4 / 6 ILE A 382
ARG A  16
GLY A 428
HIS A 296
 None
 0.92A 4oltA-2p2mA:
undetectable		 4oltA-2p2mA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB303_1
(CHITOSANASE)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		4 / 6 ILE A 382
ARG A  16
GLY A 428
HIS A 296
 None
 1.00A 4oltB-2p2mA:
undetectable		 4oltB-2p2mA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		5 / 9 TYR A 488
THR A 416
LEU A 477
VAL A 274
GLY A 273
 None
PRX  A 998 (-3.7A)
None
None
None
 1.10A 5cp4A-2p2mA:
undetectable		 5cp4A-2p2mA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_A_MMZA503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		3 / 3 ASN A  57
SER A  66
SER A  59
 None
 0.71A 5gsnA-2p2mA:
2.5		 5gsnA-2p2mA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA606_0
(ALPHA-AMYLASE)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		5 / 7 GLY A 279
GLY A 280
GLY A 472
GLY A 420
GLY A 419
 None
 0.99A 6ag0A-2p2mA:
undetectable		 6ag0A-2p2mA:
8.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6INE_A_SAMA2304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		5 / 12 GLY A 387
TRP A 414
ASP A 411
TYR A 398
ILE A 361
 PRX  A 998 (-3.4A)
PRX  A 998 (-3.4A)
PRX  A 998 (-3.6A)
None
None
 1.46A 6ineA-2p2mA:
undetectable		 6ineA-2p2mA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB7_A_PARA900_0
(AAC(3)-IIIB PROTEIN)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		5 / 10 THR A 277
THR A  74
GLY A  73
ASP A  72
GLU A  71
 None
 1.49A 6mb7A-2p2mA:
0.0		 6mb7A-2p2mA:
9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_A_NMYA303_0
(AAC(3)-IIIB PROTEIN)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		5 / 10 THR A 277
THR A  74
GLY A  73
ASP A  72
GLU A  71
 None
 1.46A 6mb9A-2p2mA:
0.0		 6mb9A-2p2mA:
9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_B_NMYB302_0
(AAC(3)-IIIB PROTEIN)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		5 / 10 THR A 277
THR A  74
GLY A  73
ASP A  72
GLU A  71
 None
 1.46A 6mb9B-2p2mA:
0.0		 6mb9B-2p2mA:
9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_C_NMYC302_0
(AAC(3)-IIIB PROTEIN)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		5 / 10 THR A 277
THR A  74
GLY A  73
ASP A  72
GLU A  71
 None
 1.43A 6mb9C-2p2mA:
0.0		 6mb9C-2p2mA:
9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_D_NMYD302_0
(AAC(3)-IIIB PROTEIN)		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		5 / 10 THR A 277
THR A  74
GLY A  73
ASP A  72
GLU A  71
 None
 1.47A 6mb9D-2p2mA:
undetectable		 6mb9D-2p2mA:
9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N7F_A_RBFA502_0
(PUTATIVE GLUTATHIONE
REDUCTASE (GR))		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		4 / 7 GLY A 279
TYR A  70
GLU A  41
GLY A  40
 None
 0.80A 6n7fA-2p2mA:
3.1		 6n7fA-2p2mA:
9.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N7F_A_RBFA502_0
(PUTATIVE GLUTATHIONE
REDUCTASE (GR))		 2p2m ACETYL-COENZYME A
SYNTHETASE
(Salmonella
enterica) 		4 / 7 GLY A 280
TYR A  70
GLU A  41
GLY A  40
 None
 0.93A 6n7fA-2p2mA:
3.1		 6n7fA-2p2mA:
9.37