SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2p2s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_A_NFZA1219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		4 / 8 ASN A 226
GLY A 224
THR A 150
PHE A 187
 None
 0.91A 1ykiA-2p2sA:
undetectable
1ykiB-2p2sA:
undetectable		 1ykiA-2p2sA:
20.51
1ykiB-2p2sA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_B_NFZB2219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		4 / 8 THR A 150
PHE A 187
ASN A 226
GLY A 224
 None
 0.90A 1ykiA-2p2sA:
undetectable
1ykiB-2p2sA:
undetectable		 1ykiA-2p2sA:
20.51
1ykiB-2p2sA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_C_NFZC3219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		4 / 8 ASN A 226
GLY A 224
THR A 150
PHE A 187
 None
 0.92A 1ykiC-2p2sA:
undetectable
1ykiD-2p2sA:
undetectable		 1ykiC-2p2sA:
20.51
1ykiD-2p2sA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_D_NFZD4219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		4 / 8 THR A 150
PHE A 187
ASN A 226
GLY A 224
 None
 0.89A 1ykiC-2p2sA:
undetectable
1ykiD-2p2sA:
undetectable		 1ykiC-2p2sA:
20.51
1ykiD-2p2sA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_1
(POL POLYPROTEIN)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 250
GLY A 136
ALA A 135
ILE A 127
ILE A 261
 None
 0.88A 2f80A-2p2sA:
undetectable		 2f80A-2p2sA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_2
(POL POLYPROTEIN)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 250
GLY A 136
ALA A 135
ILE A 127
ILE A 261
 None
 0.92A 2f80B-2p2sA:
undetectable		 2f80B-2p2sA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_1
(POL POLYPROTEIN)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 250
GLY A 136
ALA A 135
ILE A 127
ILE A 261
 None
 0.90A 2f81A-2p2sA:
undetectable		 2f81A-2p2sA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_2
(HIV-1 PROTEASE)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 250
GLY A 136
ALA A 135
ILE A 127
ILE A 261
 None
 0.85A 2hs1B-2p2sA:
undetectable		 2hs1B-2p2sA:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_1
(PROTEASE)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 250
GLY A 136
ALA A 135
ILE A 127
ILE A 261
 None
 0.96A 2hs2A-2p2sA:
undetectable		 2hs2A-2p2sA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_1
(PROTEASE)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 250
GLY A 136
ALA A 135
ILE A 127
ILE A 261
 None
 0.92A 2ienA-2p2sA:
undetectable		 2ienA-2p2sA:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMY_A_ROCA401_2
(PROTEASE)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 250
GLY A 136
ALA A 135
ILE A 127
ILE A 261
 None
 0.95A 2nmyB-2p2sA:
undetectable		 2nmyB-2p2sA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 250
GLY A 136
ALA A 135
ILE A 127
ILE A 261
 None
 0.93A 2pymA-2p2sA:
undetectable		 2pymA-2p2sA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 250
GLY A 136
ALA A 135
ILE A 127
ILE A 261
 None
 0.93A 2pymB-2p2sA:
undetectable		 2pymB-2p2sA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 250
GLY A 136
ALA A 135
ILE A 127
ILE A 261
 None
 0.97A 2pynA-2p2sA:
undetectable		 2pynA-2p2sA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 250
GLY A 136
ALA A 135
ILE A 127
ILE A 261
 None
 0.97A 2pynB-2p2sA:
undetectable		 2pynB-2p2sA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 250
GLY A 136
ALA A 135
ILE A 127
ILE A 261
 None
 0.94A 2q63B-2p2sA:
undetectable		 2q63B-2p2sA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_1
(PROTEASE RETROPEPSIN)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 250
GLY A 136
ALA A 135
ILE A 127
ILE A 261
 None
 0.96A 2q64A-2p2sA:
undetectable		 2q64A-2p2sA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 250
GLY A 136
ALA A 135
ILE A 127
ILE A 261
 None
 0.97A 2qakB-2p2sA:
undetectable		 2qakB-2p2sA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_I_AG2I671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		4 / 7 LEU A 176
ASP A 219
ILE A 334
GLN A 328
 None
None
None
EDO  A 341 (-4.2A)
 1.02A 2qqcG-2p2sA:
undetectable
2qqcJ-2p2sA:
undetectable		 2qqcG-2p2sA:
9.82
2qqcJ-2p2sA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_2
(PROTEASE RETROPEPSIN)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 250
GLY A 136
ALA A 135
ILE A 127
ILE A 261
 None
 0.89A 2rkgB-2p2sA:
undetectable		 2rkgB-2p2sA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1499_1
(CYTOCHROME P450 3A4)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		4 / 5 PHE A 296
SER A 324
PHE A  93
ILE A 325
 None
 1.19A 2v0mD-2p2sA:
undetectable		 2v0mD-2p2sA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 10 GLU A  58
ARG A  84
ILE A   9
LEU A  23
ILE A  66
 None
 1.46A 3adsA-2p2sA:
undetectable		 3adsA-2p2sA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D20_A_017A201_1
(HIV-1 PROTEASE)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 250
GLY A 136
ALA A 135
ILE A 127
ILE A 261
 None
 0.93A 3d20A-2p2sA:
undetectable		 3d20A-2p2sA:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_2
(PROTEASE)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 11 LEU A 250
GLY A 136
ALA A 135
ILE A 127
ILE A 261
 None
 0.96A 3ektD-2p2sA:
undetectable		 3ektD-2p2sA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_1
(PROTEASE)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 11 LEU A 250
GLY A 136
ALA A 135
ILE A 127
ILE A 261
 None
 0.91A 3el1A-2p2sA:
undetectable		 3el1A-2p2sA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_1
(GAG-POL POLYPROTEIN)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 250
GLY A 136
ALA A 135
ILE A 127
ILE A 261
 None
 0.90A 3jvyA-2p2sA:
undetectable		 3jvyA-2p2sA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_1
(GAG-POL POLYPROTEIN)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 250
GLY A 136
ALA A 135
ILE A 127
ILE A 261
 None
 0.90A 3jw2A-2p2sA:
undetectable		 3jw2A-2p2sA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_1
(HIV-1 PROTEASE)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 250
GLY A 136
ALA A 135
ILE A 127
ILE A 261
 None
 0.96A 3lzuA-2p2sA:
undetectable		 3lzuA-2p2sA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_1
(HIV-1 PROTEASE)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 250
GLY A 136
ALA A 135
ILE A 127
ILE A 261
 None
 0.84A 3mwsA-2p2sA:
undetectable		 3mwsA-2p2sA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_1
(PROTEASE)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 250
GLY A 136
ALA A 135
ILE A 127
ILE A 261
 None
 0.97A 3ndtC-2p2sA:
undetectable		 3ndtC-2p2sA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_2
(PROTEASE)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 250
GLY A 136
ALA A 135
ILE A 127
ILE A 261
 None
 0.95A 3nduB-2p2sA:
undetectable		 3nduB-2p2sA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_1
(PROTEASE)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 250
GLY A 136
ALA A 135
ILE A 127
ILE A 261
 None
 0.81A 3nu3A-2p2sA:
undetectable		 3nu3A-2p2sA:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWM_B_017B402_1
(PROTEASE)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 250
GLY A 136
ALA A 135
ILE A 127
ILE A 261
 None
 0.88A 3pwmA-2p2sA:
undetectable		 3pwmA-2p2sA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_1
(PROTEASE)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 250
GLY A 136
ALA A 135
ILE A 127
ILE A 261
 None
 0.92A 3pwrA-2p2sA:
undetectable		 3pwrA-2p2sA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_3
(PROTEASE)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 250
GLY A 136
ALA A 135
ILE A 127
ILE A 261
 None
 0.91A 3pwrB-2p2sA:
undetectable		 3pwrB-2p2sA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_2
(PROTEASE)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 10 LEU A 250
GLY A 136
ALA A 135
ILE A 127
ILE A 261
 None
 0.90A 3s43B-2p2sA:
undetectable		 3s43B-2p2sA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_1
(PROTEASE)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 250
GLY A 136
ALA A 135
ILE A 127
ILE A 261
 None
 0.85A 3s54A-2p2sA:
undetectable		 3s54A-2p2sA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFE_C_TMGC1_1
(SUCCINATE
DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR SUBUNIT,
MITOCHONDRIAL
SUCCINATE
DEHYDROGENASE
CYTOCHROME B560
SUBUNIT,
MITOCHONDRIAL)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		4 / 8 PRO A  98
ILE A 181
SER A 324
ILE A 325
 None
 0.82A 3sfeB-2p2sA:
undetectable
3sfeC-2p2sA:
undetectable		 3sfeB-2p2sA:
19.82
3sfeC-2p2sA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_D_9PLD1_1
(CYTOCHROME P450 2A13)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		4 / 8 PHE A 297
ALA A  28
PHE A  93
ALA A  70
 None
 0.88A 3t3sD-2p2sA:
undetectable		 3t3sD-2p2sA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_1
(PROTEASE)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 250
GLY A 136
ALA A 135
ILE A 127
ILE A 261
 None
 0.95A 3tkgA-2p2sA:
undetectable		 3tkgA-2p2sA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_2
(PROTEASE)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 250
GLY A 136
ALA A 135
ILE A 127
ILE A 261
 None
 0.91A 3tkgB-2p2sA:
undetectable		 3tkgB-2p2sA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_A_08JA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		4 / 8 VAL A 108
LEU A 105
LEU A  99
ILE A 317
 None
 0.83A 3u5kA-2p2sA:
undetectable		 3u5kA-2p2sA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_C_08JC3_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		4 / 8 VAL A 108
LEU A 105
LEU A  99
ILE A 317
 None
 0.88A 3u5kC-2p2sA:
undetectable		 3u5kC-2p2sA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_2
(PROTEASE)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		4 / 7 LEU A 250
ALA A 135
VAL A 292
ILE A 261
 None
 0.81A 3wsjB-2p2sA:
undetectable		 3wsjB-2p2sA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_A_TYLA1188_1
(BROMODOMAIN
CONTAINING 2)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		4 / 5 VAL A 108
LEU A 105
LEU A  99
ILE A 317
 None
 0.97A 4a9jA-2p2sA:
undetectable		 4a9jA-2p2sA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_B_TYLB1187_1
(BROMODOMAIN
CONTAINING 2)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		4 / 5 VAL A 108
LEU A 105
LEU A  99
ILE A 317
 None
 0.86A 4a9jB-2p2sA:
undetectable		 4a9jB-2p2sA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_C_TYLC1184_1
(BROMODOMAIN
CONTAINING 2)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		4 / 5 VAL A 108
LEU A 105
LEU A  99
ILE A 317
 None
 0.91A 4a9jC-2p2sA:
undetectable		 4a9jC-2p2sA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		4 / 6 PHE A 119
ALA A  82
PRO A  97
LEU A  99
 None
 1.07A 4dtzB-2p2sA:
undetectable		 4dtzB-2p2sA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		4 / 6 PHE A 119
ALA A  82
PRO A  97
LEU A  99
 None
 1.02A 4dubA-2p2sA:
undetectable		 4dubA-2p2sA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_1
(PROTEASE)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 250
GLY A 136
ALA A 135
ILE A 127
ILE A 261
 None
 0.96A 4hlaA-2p2sA:
undetectable		 4hlaA-2p2sA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_2
(PROTEASE)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 11 LEU A 250
GLY A 136
ALA A 135
ILE A 127
ILE A 261
 None
 0.98A 4hlaB-2p2sA:
undetectable		 4hlaB-2p2sA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_2
(HIV-1 PROTEASE)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 250
GLY A 136
ALA A 135
ILE A 127
ILE A 261
 None
 0.85A 4jecB-2p2sA:
undetectable		 4jecB-2p2sA:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 11 THR A 203
CYH A 234
ALA A 331
THR A 200
ALA A 220
 None
 1.48A 4qw3V-2p2sA:
0.4
4qw3W-2p2sA:
0.2		 4qw3V-2p2sA:
20.80
4qw3W-2p2sA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		3 / 3 PHE A 119
ILE A 317
ASP A 303
 None
 0.71A 5cswA-2p2sA:
undetectable		 5cswA-2p2sA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		3 / 3 PHE A 119
ILE A 317
ASP A 303
 None
 0.76A 5cswB-2p2sA:
undetectable		 5cswB-2p2sA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 12 THR A 203
CYH A 234
ALA A 331
THR A 200
ALA A 220
 None
 1.47A 5d0xH-2p2sA:
undetectable
5d0xI-2p2sA:
undetectable		 5d0xH-2p2sA:
20.80
5d0xI-2p2sA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_2
(HIV-1 PROTEASE)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 250
GLY A 136
ALA A 135
ILE A 127
ILE A 261
 None
 0.88A 5e5kB-2p2sA:
undetectable		 5e5kB-2p2sA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		4 / 7 ALA A 320
THR A 321
VAL A 121
HIS A 316
 None
 1.18A 5ecnA-2p2sA:
undetectable		 5ecnA-2p2sA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		4 / 7 ILE A 175
GLY A 174
LEU A 188
PHE A 187
 None
EDO  A 341 ( 4.3A)
None
None
 0.73A 5hieB-2p2sA:
undetectable		 5hieB-2p2sA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N9X_A_THRA601_0
(ADENYLATION DOMAIN)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		4 / 7 ASP A 235
GLY A 248
GLY A 246
HIS A 156
 None
 0.83A 5n9xA-2p2sA:
4.7		 5n9xA-2p2sA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_1
(PROTEASE)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 250
GLY A 136
ALA A 135
ILE A 127
ILE A 261
 None
 0.94A 5t2zA-2p2sA:
undetectable		 5t2zA-2p2sA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_2
(PROTEASE)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 250
GLY A 136
ALA A 135
ILE A 127
ILE A 261
 None
 0.85A 5t8hB-2p2sA:
undetectable		 5t8hB-2p2sA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH3_A_017A101_1
(PROTEASE)		 2p2s PUTATIVE
OXIDOREDUCTASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 250
GLY A 136
ALA A 135
ILE A 127
ILE A 261
 None
 0.85A 6dh3B-2p2sA:
undetectable		 6dh3B-2p2sA:
16.82