SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2p39'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LII_A_ADNA699_1 (ADENOSINE KINASE)	2p39	FIBROBLAST GROWTH FACTOR 23 (Homo sapiens)	5 / 12	ILE A 55 LEU A 42 GLY A 59 GLY A 104 LEU A 73	None	1.07A	1liiA-2p39A: undetectable	1liiA-2p39A: 16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G0B_A_T22A800_1 (DIPEPTIDYL PEPTIDASE 4)	2p39	FIBROBLAST GROWTH FACTOR 23 (Homo sapiens)	5 / 12	SER A 71 TYR A 70 VAL A 88 ASN A 162 HIS A 41	None	1.07A	3g0bA-2p39A: undetectable	3g0bA-2p39A: 13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G0B_B_T22B800_1 (DIPEPTIDYL PEPTIDASE 4)	2p39	FIBROBLAST GROWTH FACTOR 23 (Homo sapiens)	5 / 12	SER A 71 TYR A 70 VAL A 88 ASN A 162 HIS A 41	None	1.07A	3g0bB-2p39A: undetectable	3g0bB-2p39A: 13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G0B_C_T22C800_1 (DIPEPTIDYL PEPTIDASE 4)	2p39	FIBROBLAST GROWTH FACTOR 23 (Homo sapiens)	5 / 12	SER A 71 TYR A 70 VAL A 88 ASN A 162 HIS A 41	None	1.05A	3g0bC-2p39A: undetectable	3g0bC-2p39A: 13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G0B_D_T22D800_1 (DIPEPTIDYL PEPTIDASE 4)	2p39	FIBROBLAST GROWTH FACTOR 23 (Homo sapiens)	5 / 12	SER A 71 TYR A 70 VAL A 88 ASN A 162 HIS A 41	None	1.07A	3g0bD-2p39A: undetectable	3g0bD-2p39A: 13.39

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1LII_A_ADNA699_1","ADENOSINE KINASE","2p39","FIBROBLAST GROWTH FACTOR 23","Homo sapiens",5,"ILE A  55;LEU A  42;GLY A  59;GLY A 104;LEU A  73","None","1.07A","1liiA-2p39A:undetectable","1liiA-2p39A:16.47"],["3G0B_A_T22A800_1","DIPEPTIDYL PEPTIDASE 4","2p39","FIBROBLAST GROWTH FACTOR 23","Homo sapiens",5,"SER A  71;TYR A  70;VAL A  88;ASN A 162;HIS A  41","None","1.07A","3g0bA-2p39A:undetectable","3g0bA-2p39A:13.39"],["3G0B_B_T22B800_1","DIPEPTIDYL PEPTIDASE 4","2p39","FIBROBLAST GROWTH FACTOR 23","Homo sapiens",5,"SER A  71;TYR A  70;VAL A  88;ASN A 162;HIS A  41","None","1.07A","3g0bB-2p39A:undetectable","3g0bB-2p39A:13.39"],["3G0B_C_T22C800_1","DIPEPTIDYL PEPTIDASE 4","2p39","FIBROBLAST GROWTH FACTOR 23","Homo sapiens",5,"SER A  71;TYR A  70;VAL A  88;ASN A 162;HIS A  41","None","1.05A","3g0bC-2p39A:undetectable","3g0bC-2p39A:13.39"],["3G0B_D_T22D800_1","DIPEPTIDYL PEPTIDASE 4","2p39","FIBROBLAST GROWTH FACTOR 23","Homo sapiens",5,"SER A  71;TYR A  70;VAL A  88;ASN A 162;HIS A  41","None","1.07A","3g0bD-2p39A:undetectable","3g0bD-2p39A:13.39"]]