SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2p3g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_B_IPBB600_0
(ODORANT-BINDING
PROTEIN)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 4 ILE X 170
MET X 253
VAL X 331
GLY X 171
 None
 1.16A 1e06B-2p3gX:
undetectable		 1e06B-2p3gX:
21.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FMO_E_ADNE351_1
(CAMP-DEPENDENT
PROTEIN KINASE)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		8 / 12 LEU X  70
GLY X  71
VAL X  78
ALA X  91
ASN X 191
LEU X 193
THR X 206
ASP X 207
 F10  X 401 (-3.9A)
F10  X 401 ( 4.3A)
None
F10  X 401 (-3.4A)
None
F10  X 401 ( 4.4A)
F10  X 401 (-3.8A)
F10  X 401 (-3.4A)
 0.92A 1fmoE-2p3gX:
20.4		 1fmoE-2p3gX:
30.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FMO_E_ADNE351_1
(CAMP-DEPENDENT
PROTEIN KINASE)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		8 / 12 LEU X  70
GLY X  71
VAL X  78
ALA X  91
VAL X 118
ASN X 191
THR X 206
ASP X 207
 F10  X 401 (-3.9A)
F10  X 401 ( 4.3A)
None
F10  X 401 (-3.4A)
None
None
F10  X 401 (-3.8A)
F10  X 401 (-3.4A)
 0.78A 1fmoE-2p3gX:
20.4		 1fmoE-2p3gX:
30.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 7 ILE X 252
MET X 356
THR X 357
LEU X 360
 None
 0.80A 1v54N-2p3gX:
undetectable
1v54W-2p3gX:
undetectable		 1v54N-2p3gX:
19.81
1v54W-2p3gX:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 7 ILE X 252
MET X 356
THR X 357
LEU X 360
 None
 0.81A 1v55A-2p3gX:
undetectable
1v55J-2p3gX:
undetectable		 1v55A-2p3gX:
19.81
1v55J-2p3gX:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 8 ILE X 252
MET X 356
THR X 357
LEU X 360
 None
 0.84A 1v55N-2p3gX:
undetectable
1v55W-2p3gX:
undetectable		 1v55N-2p3gX:
19.81
1v55W-2p3gX:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_F_SAMF301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		3 / 3 LYS X 100
ASP X 241
CYH X 244
 None
 1.27A 2br4F-2p3gX:
undetectable		 2br4F-2p3gX:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 7 ILE X 252
MET X 356
THR X 357
LEU X 360
 None
 0.86A 2dyrN-2p3gX:
undetectable
2dyrW-2p3gX:
undetectable		 2dyrN-2p3gX:
19.81
2dyrW-2p3gX:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 8 ILE X 252
MET X 356
THR X 357
LEU X 360
 None
 0.78A 2einA-2p3gX:
undetectable
2einJ-2p3gX:
undetectable		 2einA-2p3gX:
19.81
2einJ-2p3gX:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 6 ILE X 252
MET X 356
THR X 357
LEU X 360
 None
 0.77A 2einN-2p3gX:
0.0
2einW-2p3gX:
undetectable		 2einN-2p3gX:
19.81
2einW-2p3gX:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1004_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 7 VAL X 294
SER X 292
LEU X 336
HIS X 337
 None
 1.12A 2f78B-2p3gX:
undetectable		 2f78B-2p3gX:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 6 VAL X 294
SER X 292
LEU X 336
HIS X 337
 None
 1.16A 2f8dA-2p3gX:
undetectable		 2f8dA-2p3gX:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_A_MIXA539_1
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		7 / 12 GLY X  71
VAL X  78
ALA X  91
ASP X 186
LYS X 188
ASN X 191
ASP X 207
 F10  X 401 ( 4.3A)
None
F10  X 401 (-3.4A)
None
None
None
F10  X 401 (-3.4A)
 0.81A 2fumA-2p3gX:
21.1		 2fumA-2p3gX:
25.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_A_MIXA539_1
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		7 / 12 LEU X  70
GLY X  71
VAL X  78
ALA X  91
ASP X 186
LYS X 188
ASN X 191
 F10  X 401 (-3.9A)
F10  X 401 ( 4.3A)
None
F10  X 401 (-3.4A)
None
None
None
 0.79A 2fumA-2p3gX:
21.1		 2fumA-2p3gX:
25.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_B_MIXB1539_1
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		7 / 12 GLY X  71
VAL X  78
ALA X  91
MET X 138
LYS X 188
ASN X 191
ASP X 207
 F10  X 401 ( 4.3A)
None
F10  X 401 (-3.4A)
F10  X 401 ( 4.0A)
None
None
F10  X 401 (-3.4A)
 0.79A 2fumB-2p3gX:
21.1		 2fumB-2p3gX:
25.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_B_MIXB1539_1
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		7 / 12 LEU X  70
GLY X  71
VAL X  78
ALA X  91
MET X 138
LYS X 188
ASN X 191
 F10  X 401 (-3.9A)
F10  X 401 ( 4.3A)
None
F10  X 401 (-3.4A)
F10  X 401 ( 4.0A)
None
None
 0.78A 2fumB-2p3gX:
21.1		 2fumB-2p3gX:
25.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_C_MIXC2539_1
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		6 / 12 LEU X  70
GLY X  71
VAL X  78
ALA X  91
MET X 138
ASN X 191
 F10  X 401 (-3.9A)
F10  X 401 ( 4.3A)
None
F10  X 401 (-3.4A)
F10  X 401 ( 4.0A)
None
 0.75A 2fumC-2p3gX:
19.9		 2fumC-2p3gX:
25.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_D_MIXD3539_1
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		8 / 12 LEU X  70
GLY X  71
GLY X  73
VAL X  78
ALA X  91
MET X 138
LYS X 188
ASN X 191
 F10  X 401 (-3.9A)
F10  X 401 ( 4.3A)
F10  X 401 ( 4.1A)
None
F10  X 401 (-3.4A)
F10  X 401 ( 4.0A)
None
None
 1.07A 2fumD-2p3gX:
20.0		 2fumD-2p3gX:
25.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_A_STIA600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		5 / 6 LEU X  70
LYS X  93
VAL X 118
ILE X 136
ARG X 185
 F10  X 401 (-3.9A)
F10  X 401 (-4.3A)
None
None
None
 0.98A 2hyyA-2p3gX:
17.5		 2hyyA-2p3gX:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_B_STIB600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 6 LEU X  70
LYS X  93
VAL X 118
ILE X 136
 F10  X 401 (-3.9A)
F10  X 401 (-4.3A)
None
None
 0.72A 2hyyB-2p3gX:
17.6		 2hyyB-2p3gX:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		5 / 12 GLY X  73
GLY X  71
LEU X 203
GLU X 145
ASP X 207
 F10  X 401 ( 4.1A)
F10  X 401 ( 4.3A)
None
None
F10  X 401 (-3.4A)
 0.88A 2oxtA-2p3gX:
undetectable		 2oxtA-2p3gX:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFX_A_VGHA9000_1
(TYROSINE-PROTEIN
KINASE RECEPTOR)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 8 LEU X  70
ALA X  91
MET X 138
ASP X 207
 F10  X 401 (-3.9A)
F10  X 401 (-3.4A)
F10  X 401 ( 4.0A)
F10  X 401 (-3.4A)
 0.58A 2yfxA-2p3gX:
19.0		 2yfxA-2p3gX:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 8 ILE X 252
MET X 356
THR X 357
LEU X 360
 None
 0.80A 3abkA-2p3gX:
undetectable
3abkJ-2p3gX:
undetectable		 3abkA-2p3gX:
19.81
3abkJ-2p3gX:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 7 ILE X 252
MET X 356
THR X 357
LEU X 360
 None
 0.80A 3ablA-2p3gX:
undetectable
3ablJ-2p3gX:
undetectable		 3ablA-2p3gX:
19.81
3ablJ-2p3gX:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 8 ILE X 252
MET X 356
THR X 357
LEU X 360
 None
 0.82A 3abmN-2p3gX:
undetectable
3abmW-2p3gX:
undetectable		 3abmN-2p3gX:
19.81
3abmW-2p3gX:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 6 ILE X 252
MET X 356
THR X 357
LEU X 360
 None
 0.66A 3ag1N-2p3gX:
1.7
3ag1W-2p3gX:
undetectable		 3ag1N-2p3gX:
19.81
3ag1W-2p3gX:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 7 ILE X 252
MET X 356
THR X 357
LEU X 360
 None
 0.83A 3ag3A-2p3gX:
undetectable
3ag3J-2p3gX:
undetectable		 3ag3A-2p3gX:
19.81
3ag3J-2p3gX:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 8 ILE X 252
MET X 356
THR X 357
LEU X 360
 None
 0.84A 3ag3N-2p3gX:
0.0
3ag3W-2p3gX:
undetectable		 3ag3N-2p3gX:
19.81
3ag3W-2p3gX:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 8 ILE X 252
MET X 356
THR X 357
LEU X 360
 None
 0.85A 3asoN-2p3gX:
undetectable
3asoW-2p3gX:
undetectable		 3asoN-2p3gX:
19.81
3asoW-2p3gX:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CS9_A_NILA600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		5 / 10 LEU X  70
VAL X  78
LYS X  93
VAL X 118
ILE X 136
 F10  X 401 (-3.9A)
None
F10  X 401 (-4.3A)
None
None
 0.74A 3cs9A-2p3gX:
17.7		 3cs9A-2p3gX:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CS9_B_NILB600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		5 / 9 LEU X  70
VAL X  78
LYS X  93
VAL X 118
ILE X 136
 F10  X 401 (-3.9A)
None
F10  X 401 (-4.3A)
None
None
 0.74A 3cs9B-2p3gX:
18.2		 3cs9B-2p3gX:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CS9_C_NILC600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		5 / 9 LEU X  70
VAL X  78
LYS X  93
VAL X 118
ILE X 136
 F10  X 401 (-3.9A)
None
F10  X 401 (-4.3A)
None
None
 0.78A 3cs9C-2p3gX:
17.7		 3cs9C-2p3gX:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK3_B_0LIB2_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 7 LEU X  70
LYS X  93
ILE X 136
ARG X 185
 F10  X 401 (-3.9A)
F10  X 401 (-4.3A)
None
None
 1.04A 3ik3B-2p3gX:
17.5		 3ik3B-2p3gX:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K5V_A_STIA2_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 6 LEU X  70
LYS X  93
VAL X 118
ILE X 136
 F10  X 401 (-3.9A)
F10  X 401 (-4.3A)
None
None
 0.77A 3k5vA-2p3gX:
17.6		 3k5vA-2p3gX:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K5V_B_STIB2_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 6 LEU X  70
LYS X  93
VAL X 118
ILE X 136
 F10  X 401 (-3.9A)
F10  X 401 (-4.3A)
None
None
 0.78A 3k5vB-2p3gX:
17.5		 3k5vB-2p3gX:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 6 LYS X  93
VAL X 118
ILE X 136
ARG X 185
 F10  X 401 (-4.3A)
None
None
None
 1.06A 3ms9A-2p3gX:
17.6		 3ms9A-2p3gX:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 7 LYS X  93
VAL X 118
ILE X 136
ARG X 185
 F10  X 401 (-4.3A)
None
None
None
 1.12A 3ms9B-2p3gX:
17.3		 3ms9B-2p3gX:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 6 LYS X  93
VAL X 118
ILE X 136
ARG X 185
 F10  X 401 (-4.3A)
None
None
None
 1.07A 3mssA-2p3gX:
17.7		 3mssA-2p3gX:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_C_STIC1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 6 LYS X  93
VAL X 118
ILE X 136
ARG X 185
 F10  X 401 (-4.3A)
None
None
None
 1.08A 3mssC-2p3gX:
17.7		 3mssC-2p3gX:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_D_STID1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 6 VAL X  78
LYS X  93
VAL X 118
ILE X 136
 None
F10  X 401 (-4.3A)
None
None
 0.70A 3mssD-2p3gX:
17.6		 3mssD-2p3gX:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXZ_A_0LIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		5 / 9 LEU X  70
LYS X  93
ILE X 136
ARG X 185
LEU X 193
 F10  X 401 (-3.9A)
F10  X 401 (-4.3A)
None
None
F10  X 401 ( 4.4A)
 1.28A 3oxzA-2p3gX:
17.9		 3oxzA-2p3gX:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 6 ILE X 252
MET X 356
THR X 357
LEU X 360
 None
 0.86A 3wg7N-2p3gX:
undetectable
3wg7W-2p3gX:
undetectable		 3wg7N-2p3gX:
19.81
3wg7W-2p3gX:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAA_A_RTZA401_1
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		6 / 11 VAL X  78
ALA X  91
LYS X  93
GLU X 190
LEU X 193
ASP X 207
 None
F10  X 401 (-3.4A)
F10  X 401 (-4.3A)
None
F10  X 401 ( 4.4A)
F10  X 401 (-3.4A)
 1.09A 4iaaA-2p3gX:
20.6		 4iaaA-2p3gX:
29.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA505_0
(RNA POLYMERASE
3D-POL)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		3 / 3 CYH X  98
ASN X  75
LYS X 100
 None
 1.17A 4k50A-2p3gX:
0.9		 4k50A-2p3gX:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9I_A_8PRA601_1
(RHODOPSIN KINASE)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 7 VAL X  78
ALA X  91
LEU X  95
MET X 138
 None
F10  X 401 (-3.4A)
None
F10  X 401 ( 4.0A)
 0.76A 4l9iA-2p3gX:
6.6		 4l9iA-2p3gX:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9I_A_8PRA601_1
(RHODOPSIN KINASE)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 7 VAL X  78
ALA X  91
MET X 138
LEU X 193
 None
F10  X 401 (-3.4A)
F10  X 401 ( 4.0A)
F10  X 401 ( 4.4A)
 0.72A 4l9iA-2p3gX:
6.6		 4l9iA-2p3gX:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9I_B_8PRB601_1
(RHODOPSIN KINASE)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		5 / 8 GLY X  73
VAL X  78
ALA X  91
LYS X  93
MET X 138
 F10  X 401 ( 4.1A)
None
F10  X 401 (-3.4A)
F10  X 401 (-4.3A)
F10  X 401 ( 4.0A)
 1.03A 4l9iB-2p3gX:
18.7		 4l9iB-2p3gX:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9I_B_8PRB601_1
(RHODOPSIN KINASE)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		5 / 8 GLY X  73
VAL X  78
ALA X  91
MET X 138
LEU X 193
 F10  X 401 ( 4.1A)
None
F10  X 401 (-3.4A)
F10  X 401 ( 4.0A)
F10  X 401 ( 4.4A)
 0.96A 4l9iB-2p3gX:
18.7		 4l9iB-2p3gX:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_B_ACTB603_0
(CHOLINE OXIDASE)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		3 / 3 SER X 339
ARG X 340
HIS X 337
 None
 1.02A 4mjwA-2p3gX:
undetectable
4mjwB-2p3gX:
undetectable		 4mjwA-2p3gX:
19.82
4mjwB-2p3gX:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MS4_A_2C0A501_1
(GAMMA-AMINOBUTYRIC
ACID TYPE B RECEPTOR
SUBUNIT 1)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 8 SER X 169
TYR X 194
ILE X 202
GLU X 165
 None
 1.36A 4ms4A-2p3gX:
undetectable		 4ms4A-2p3gX:
19.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O0W_A_ADNA501_1
(AURORA KINASE A)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		5 / 6 LEU X  70
GLY X  71
VAL X  78
ALA X  91
LEU X 193
 F10  X 401 (-3.9A)
F10  X 401 ( 4.3A)
None
F10  X 401 (-3.4A)
F10  X 401 ( 4.4A)
 0.97A 4o0wA-2p3gX:
20.8		 4o0wA-2p3gX:
31.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OGR_E_ADNE401_1
(CYCLIN-DEPENDENT
KINASE 9)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		5 / 7 GLY X  71
ALA X  91
ASN X 191
LEU X 193
ASP X 207
 F10  X 401 ( 4.3A)
F10  X 401 (-3.4A)
None
F10  X 401 ( 4.4A)
F10  X 401 (-3.4A)
 1.28A 4ogrE-2p3gX:
19.4		 4ogrE-2p3gX:
25.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QRC_A_0LIA802_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		5 / 8 LEU X  70
VAL X  78
LYS X  93
HIS X 184
LEU X 193
 F10  X 401 (-3.9A)
None
F10  X 401 (-4.3A)
None
F10  X 401 ( 4.4A)
 1.16A 4qrcA-2p3gX:
12.3		 4qrcA-2p3gX:
26.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TYJ_A_0LIA801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 6 LEU X  70
VAL X  78
LYS X  93
ILE X 117
 F10  X 401 (-3.9A)
None
F10  X 401 (-4.3A)
None
 0.56A 4tyjA-2p3gX:
17.8		 4tyjA-2p3gX:
26.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WBO_B_ANWB601_0
(RHODOPSIN KINASE)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 8 LEU X  70
ALA X  91
MET X 138
LEU X 193
 F10  X 401 (-3.9A)
F10  X 401 (-3.4A)
F10  X 401 ( 4.0A)
F10  X 401 ( 4.4A)
 0.67A 4wboB-2p3gX:
18.5		 4wboB-2p3gX:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WBO_C_ANWC601_0
(RHODOPSIN KINASE)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 6 LEU X  70
ALA X  91
MET X 138
LEU X 193
 F10  X 401 (-3.9A)
F10  X 401 (-3.4A)
F10  X 401 ( 4.0A)
F10  X 401 ( 4.4A)
 0.73A 4wboC-2p3gX:
18.6		 4wboC-2p3gX:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_D_LOCD502_1
(TUBULIN BETA CHAIN)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		5 / 12 LEU X 257
LYS X 299
LEU X 301
ALA X 163
ILE X 325
 None
 1.12A 4x1iD-2p3gX:
undetectable		 4x1iD-2p3gX:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 7 ILE X 252
MET X 356
THR X 357
LEU X 360
 None
 0.77A 5b1aA-2p3gX:
undetectable
5b1aJ-2p3gX:
undetectable		 5b1aA-2p3gX:
19.81
5b1aJ-2p3gX:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 7 ILE X 252
MET X 356
THR X 357
LEU X 360
 None
 0.81A 5b1bA-2p3gX:
1.8
5b1bJ-2p3gX:
undetectable		 5b1bA-2p3gX:
19.81
5b1bJ-2p3gX:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 7 ILE X 252
MET X 356
THR X 357
LEU X 360
 None
 0.84A 5b1bN-2p3gX:
undetectable
5b1bW-2p3gX:
undetectable		 5b1bN-2p3gX:
19.81
5b1bW-2p3gX:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 7 ILE X 252
MET X 356
THR X 357
LEU X 360
 None
 0.78A 5b3sA-2p3gX:
1.6
5b3sJ-2p3gX:
undetectable		 5b3sA-2p3gX:
19.81
5b3sJ-2p3gX:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 7 ILE X 252
MET X 356
THR X 357
LEU X 360
 None
 0.81A 5b3sN-2p3gX:
undetectable
5b3sW-2p3gX:
undetectable		 5b3sN-2p3gX:
19.81
5b3sW-2p3gX:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 7 ILE X 252
MET X 356
THR X 357
LEU X 360
 None
 0.80A 5iy5A-2p3gX:
undetectable
5iy5J-2p3gX:
undetectable		 5iy5A-2p3gX:
19.81
5iy5J-2p3gX:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 7 ILE X 252
MET X 356
THR X 357
LEU X 360
 None
 0.80A 5iy5N-2p3gX:
undetectable
5iy5W-2p3gX:
undetectable		 5iy5N-2p3gX:
19.81
5iy5W-2p3gX:
13.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N3H_A_NCAA401_0
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		6 / 10 LEU X  70
VAL X  78
ALA X  91
MET X 138
LEU X 193
THR X 206
 F10  X 401 (-3.9A)
None
F10  X 401 (-3.4A)
F10  X 401 ( 4.0A)
F10  X 401 ( 4.4A)
F10  X 401 (-3.8A)
 0.82A 5n3hA-2p3gX:
20.0		 5n3hA-2p3gX:
30.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N3H_A_NCAA401_0
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		6 / 10 LEU X  70
VAL X  78
ALA X  91
VAL X 118
MET X 138
THR X 206
 F10  X 401 (-3.9A)
None
F10  X 401 (-3.4A)
None
F10  X 401 ( 4.0A)
F10  X 401 (-3.8A)
 0.59A 5n3hA-2p3gX:
20.0		 5n3hA-2p3gX:
30.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC3_A_DB8A601_2
(WEE1-LIKE PROTEIN
KINASE)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 4 VAL X  78
LYS X  93
VAL X 118
ASN X 191
 None
F10  X 401 (-4.3A)
None
None
 0.75A 5vc3A-2p3gX:
20.1		 5vc3A-2p3gX:
25.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W5V_A_ANWA701_0
(SERINE/THREONINE-PRO
TEIN KINASE TBK1)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		5 / 9 LEU X  70
ALA X  91
VAL X 118
MET X 138
THR X 206
 F10  X 401 (-3.9A)
F10  X 401 (-3.4A)
None
F10  X 401 ( 4.0A)
F10  X 401 (-3.8A)
 0.94A 5w5vA-2p3gX:
4.2		 5w5vA-2p3gX:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 7 ILE X 252
MET X 356
THR X 357
LEU X 360
 None
 0.94A 5xdqA-2p3gX:
undetectable
5xdqJ-2p3gX:
undetectable		 5xdqA-2p3gX:
19.81
5xdqJ-2p3gX:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 7 ILE X 252
MET X 356
THR X 357
LEU X 360
 None
 0.76A 5xdxA-2p3gX:
1.3
5xdxJ-2p3gX:
undetectable		 5xdxA-2p3gX:
19.81
5xdxJ-2p3gX:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 8 ILE X 252
MET X 356
THR X 357
LEU X 360
 None
 0.80A 5xdxN-2p3gX:
undetectable
5xdxW-2p3gX:
undetectable		 5xdxN-2p3gX:
19.81
5xdxW-2p3gX:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XPR_A_K86A1201_1
(ENDOTHELIN B
RECEPTOR,ENDOLYSIN,E
NDOTHELIN B RECEPTOR)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		5 / 12 VAL X 187
LEU X 177
HIS X 178
ILE X 117
ALA X 173
 None
 1.47A 5xprA-2p3gX:
undetectable		 5xprA-2p3gX:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 6 ILE X 252
MET X 356
THR X 357
LEU X 360
 None
 0.80A 5z86N-2p3gX:
undetectable
5z86W-2p3gX:
undetectable		 5z86N-2p3gX:
19.81
5z86W-2p3gX:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 8 ILE X 252
MET X 356
THR X 357
LEU X 360
 None
 0.78A 5zcoA-2p3gX:
undetectable
5zcoJ-2p3gX:
undetectable		 5zcoA-2p3gX:
19.81
5zcoJ-2p3gX:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 6 ILE X 252
MET X 356
THR X 357
LEU X 360
 None
 0.79A 5zcoN-2p3gX:
undetectable
5zcoW-2p3gX:
undetectable		 5zcoN-2p3gX:
19.81
5zcoW-2p3gX:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 7 ILE X 252
MET X 356
THR X 357
LEU X 360
 None
 0.77A 5zcpA-2p3gX:
undetectable
5zcpJ-2p3gX:
undetectable		 5zcpA-2p3gX:
19.81
5zcpJ-2p3gX:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 8 ILE X 252
MET X 356
THR X 357
LEU X 360
 None
 0.79A 5zcpN-2p3gX:
undetectable
5zcpW-2p3gX:
undetectable		 5zcpN-2p3gX:
19.81
5zcpW-2p3gX:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 7 ILE X 252
MET X 356
THR X 357
LEU X 360
 None
 0.78A 5zcqA-2p3gX:
undetectable
5zcqJ-2p3gX:
undetectable		 5zcqA-2p3gX:
19.81
5zcqJ-2p3gX:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 8 ILE X 252
MET X 356
THR X 357
LEU X 360
 None
 0.83A 5zcqN-2p3gX:
undetectable
5zcqW-2p3gX:
undetectable		 5zcqN-2p3gX:
19.81
5zcqW-2p3gX:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA810_0
(GEPHYRIN)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		3 / 3 LEU X 146
SER X 148
PHE X 147
 None
 0.67A 6fgcA-2p3gX:
undetectable		 6fgcA-2p3gX:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 7 ILE X 252
MET X 356
THR X 357
LEU X 360
 None
 0.67A 6nmfA-2p3gX:
1.2
6nmfJ-2p3gX:
undetectable		 6nmfA-2p3gX:
19.81
6nmfJ-2p3gX:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens) 		4 / 7 ILE X 252
MET X 356
THR X 357
LEU X 360
 None
 0.69A 6nmpA-2p3gX:
undetectable
6nmpJ-2p3gX:
undetectable		 6nmpA-2p3gX:
19.81
6nmpJ-2p3gX:
13.79