SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2p3h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2RLF_A_RIMA199_1 (MATRIX PROTEIN 2)	2p3h	UNCHARACTERIZED CBS DOMAIN-CONTAINING PROTEIN (Corynebacterium glutamicum)	4 / 6	LEU A 82 LEU A 101 ILE A 84 ARG A 83	None	1.03A	2rlfA-2p3hA: undetectable 2rlfB-2p3hA: undetectable	2rlfA-2p3hA: 22.77 2rlfB-2p3hA: 22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4F4D_B_CHDB504_0 (FERROCHELATASE, MITOCHONDRIAL)	2p3h	UNCHARACTERIZED CBS DOMAIN-CONTAINING PROTEIN (Corynebacterium glutamicum)	4 / 4	LEU A 34 PRO A 35 LEU A 45 ILE A 42	None	0.99A	4f4dB-2p3hA: undetectable	4f4dB-2p3hA: 14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KLR_A_CHDA505_0 (FERROCHELATASE, MITOCHONDRIAL)	2p3h	UNCHARACTERIZED CBS DOMAIN-CONTAINING PROTEIN (Corynebacterium glutamicum)	4 / 5	LEU A 34 PRO A 35 LEU A 45 ILE A 42	None	0.95A	4klrA-2p3hA: undetectable	4klrA-2p3hA: 15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F6I_A_8PRA509_1 (ENVELOPE GLYCOPROTEIN,GP,GP1 ENVELOPE GLYCOPROTEIN)	2p3h	UNCHARACTERIZED CBS DOMAIN-CONTAINING PROTEIN (Corynebacterium glutamicum)	5 / 12	VAL A 26 LEU A 34 GLU A 25 ALA A 29 LEU A 82	None None None EDO A 301 ( 4.2A) None	1.15A	6f6iA-2p3hA: undetectable 6f6iB-2p3hA: undetectable	6f6iA-2p3hA: 17.89 6f6iB-2p3hA: 28.16

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2RLF_A_RIMA199_1","MATRIX PROTEIN 2;MATRIX PROTEIN 2","2p3h","UNCHARACTERIZED CBS DOMAIN-CONTAINING PROTEIN","Corynebacterium glutamicum",4,"LEU A  82;LEU A 101;ILE A  84;ARG A  83","None","1.03A","2rlfA-2p3hA:undetectable;2rlfB-2p3hA:undetectable","2rlfA-2p3hA:22.77;2rlfB-2p3hA:22.77"],["4F4D_B_CHDB504_0","FERROCHELATASE, MITOCHONDRIAL","2p3h","UNCHARACTERIZED CBS DOMAIN-CONTAINING PROTEIN","Corynebacterium glutamicum",4,"LEU A  34;PRO A  35;LEU A  45;ILE A  42","None","0.99A","4f4dB-2p3hA:undetectable","4f4dB-2p3hA:14.21"],["4KLR_A_CHDA505_0","FERROCHELATASE, MITOCHONDRIAL","2p3h","UNCHARACTERIZED CBS DOMAIN-CONTAINING PROTEIN","Corynebacterium glutamicum",4,"LEU A  34;PRO A  35;LEU A  45;ILE A  42","None","0.95A","4klrA-2p3hA:undetectable","4klrA-2p3hA:15.53"],["6F6I_A_8PRA509_1","ENVELOPE GLYCOPROTEIN,GP,GP1;ENVELOPE GLYCOPROTEIN","2p3h","UNCHARACTERIZED CBS DOMAIN-CONTAINING PROTEIN","Corynebacterium glutamicum",5,"VAL A  26;LEU A  34;GLU A  25;ALA A  29;LEU A  82","None;None;None;EDO A 301 ( 4.2A);None","1.15A","6f6iA-2p3hA:undetectable;6f6iB-2p3hA:undetectable","6f6iA-2p3hA:17.89;6f6iB-2p3hA:28.16"]]