SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2p3j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QZR_B_CDXB901_2 (DNA TOPOISOMERASE II)	2p3j	VP4 (Rotavirus A)	4 / 7	THR A 186 TYR A 177 ASN A 183 LEU A 158	None	1.03A	1qzrB-2p3jA: undetectable	1qzrB-2p3jA: 15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZUJ_A_CAMA422_0 (CAMPHOR 5-MONOOXYGENASE)	2p3j	VP4 (Rotavirus A)	4 / 8	TYR A 165 THR A 176 VAL A 144 LEU A 103	None	0.87A	2zujA-2p3jA: undetectable	2zujA-2p3jA: 17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LXI_A_CAMA423_0 (CYTOCHROME P450)	2p3j	VP4 (Rotavirus A)	5 / 10	THR A 191 THR A 176 LEU A 103 GLY A 95 VAL A 167	None	1.19A	3lxiA-2p3jA: undetectable	3lxiA-2p3jA: 14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LXI_B_CAMB423_0 (CYTOCHROME P450)	2p3j	VP4 (Rotavirus A)	5 / 11	THR A 191 THR A 176 LEU A 103 GLY A 95 VAL A 167	None	1.15A	3lxiB-2p3jA: undetectable	3lxiB-2p3jA: 14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C9N_B_CAMB1420_0 (CYTOCHROME P450)	2p3j	VP4 (Rotavirus A)	5 / 10	THR A 191 THR A 176 LEU A 103 GLY A 95 VAL A 167	None	1.20A	4c9nB-2p3jA: undetectable	4c9nB-2p3jA: 14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C9P_A_CAMA423_0 (CYTOCHROME P450)	2p3j	VP4 (Rotavirus A)	5 / 9	THR A 191 THR A 176 LEU A 103 GLY A 95 VAL A 167	None	1.21A	4c9pA-2p3jA: undetectable	4c9pA-2p3jA: 14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C9P_B_CAMB423_0 (CYTOCHROME P450)	2p3j	VP4 (Rotavirus A)	5 / 10	THR A 191 THR A 176 LEU A 103 GLY A 95 VAL A 167	None	1.17A	4c9pB-2p3jA: undetectable	4c9pB-2p3jA: 14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JX1_F_CAMF502_0 (CAMPHOR 5-MONOOXYGENASE)	2p3j	VP4 (Rotavirus A)	4 / 4	TYR A 152 THR A 120 VAL A 91 ILE A 128	None	1.44A	4jx1F-2p3jA: undetectable	4jx1F-2p3jA: 17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DZK_2_BEZ2801_0 (ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 BEZ-LEU-LEU)	2p3j	VP4 (Rotavirus A)	4 / 4	LEU A 107 ARG A 117 ILE A 106 ILE A 130	None	1.22A	5dzk2-2p3jA: undetectable 5dzkM-2p3jA: undetectable 5dzkN-2p3jA: undetectable	5dzk2-2p3jA: 1.24 5dzkM-2p3jA: 20.49 5dzkN-2p3jA: 20.49

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1QZR_B_CDXB901_2","DNA TOPOISOMERASE II","2p3j","VP4","Rotavirus A",4,"THR A 186;TYR A 177;ASN A 183;LEU A 158","None","1.03A","1qzrB-2p3jA:undetectable","1qzrB-2p3jA:15.94"],["2ZUJ_A_CAMA422_0","CAMPHOR 5-MONOOXYGENASE","2p3j","VP4","Rotavirus A",4,"TYR A 165;THR A 176;VAL A 144;LEU A 103","None","0.87A","2zujA-2p3jA:undetectable","2zujA-2p3jA:17.71"],["3LXI_A_CAMA423_0","CYTOCHROME P450","2p3j","VP4","Rotavirus A",5,"THR A 191;THR A 176;LEU A 103;GLY A  95;VAL A 167","None","1.19A","3lxiA-2p3jA:undetectable","3lxiA-2p3jA:14.36"],["3LXI_B_CAMB423_0","CYTOCHROME P450","2p3j","VP4","Rotavirus A",5,"THR A 191;THR A 176;LEU A 103;GLY A  95;VAL A 167","None","1.15A","3lxiB-2p3jA:undetectable","3lxiB-2p3jA:14.36"],["4C9N_B_CAMB1420_0","CYTOCHROME P450","2p3j","VP4","Rotavirus A",5,"THR A 191;THR A 176;LEU A 103;GLY A  95;VAL A 167","None","1.20A","4c9nB-2p3jA:undetectable","4c9nB-2p3jA:14.36"],["4C9P_A_CAMA423_0","CYTOCHROME P450","2p3j","VP4","Rotavirus A",5,"THR A 191;THR A 176;LEU A 103;GLY A  95;VAL A 167","None","1.21A","4c9pA-2p3jA:undetectable","4c9pA-2p3jA:14.36"],["4C9P_B_CAMB423_0","CYTOCHROME P450","2p3j","VP4","Rotavirus A",5,"THR A 191;THR A 176;LEU A 103;GLY A  95;VAL A 167","None","1.17A","4c9pB-2p3jA:undetectable","4c9pB-2p3jA:14.36"],["4JX1_F_CAMF502_0","CAMPHOR 5-MONOOXYGENASE","2p3j","VP4","Rotavirus A",4,"TYR A 152;THR A 120;VAL A  91;ILE A 128","None","1.44A","4jx1F-2p3jA:undetectable","4jx1F-2p3jA:17.63"],["5DZK_2_BEZ2801_0","ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1;BEZ-LEU-LEU","2p3j","VP4","Rotavirus A",4,"LEU A 107;ARG A 117;ILE A 106;ILE A 130","None","1.22A","5dzk2-2p3jA:undetectable;5dzkM-2p3jA:undetectable;5dzkN-2p3jA:undetectable","5dzk2-2p3jA:1.24;5dzkM-2p3jA:20.49;5dzkN-2p3jA:20.49"]]