SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2p3p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_C_9PLC501_1
(CYTOCHROME P450 2E1)		 2p3p HYPOTHETICAL PROTEIN
(Porphyromonas
gingivalis) 		4 / 5 PHE A  73
PHE A 118
THR A 129
LEU A  81
 None
 1.09A 3t3zC-2p3pA:
undetectable		 3t3zC-2p3pA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QT2_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 2p3p HYPOTHETICAL PROTEIN
(Porphyromonas
gingivalis) 		5 / 10 ASP A 221
GLU A 134
VAL A 152
ILE A 164
PHE A 259
 None
 1.39A 4qt2A-2p3pA:
undetectable		 4qt2A-2p3pA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QT3_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 2p3p HYPOTHETICAL PROTEIN
(Porphyromonas
gingivalis) 		5 / 10 ASP A 221
GLU A 134
VAL A 152
ILE A 164
PHE A 259
 None
 1.40A 4qt3A-2p3pA:
undetectable		 4qt3A-2p3pA:
21.95