SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2p3v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RV7_B_AB1B1001_1
(PROTEASE)		 2p3v INOSITOL-1-MONOPHOSP
HATASE
(Thermotoga
maritima) 		5 / 11 ALA A1204
ILE A1197
VAL A1111
ALA A1224
VAL A1216
 None
 1.09A 1rv7A-2p3vA:
undetectable
1rv7B-2p3vA:
undetectable		 1rv7A-2p3vA:
17.32
1rv7B-2p3vA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J5M_A_ACTA1321_0
(CHLOROPEROXIDASE)		 2p3v INOSITOL-1-MONOPHOSP
HATASE
(Thermotoga
maritima) 		4 / 6 LEU A1017
PHE A1087
ILE A1081
ALA A1045
 None
 1.09A 2j5mA-2p3vA:
undetectable		 2j5mA-2p3vA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 2p3v INOSITOL-1-MONOPHOSP
HATASE
(Thermotoga
maritima) 		4 / 7 PHE A1006
LEU A1010
LEU A1011
GLU A1060
 None
 1.00A 2jn3A-2p3vA:
2.3		 2jn3A-2p3vA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_A_ADNA1_1
(YTAA PROTEIN)		 2p3v INOSITOL-1-MONOPHOSP
HATASE
(Thermotoga
maritima) 		4 / 7 ILE A1078
ILE A1041
LEU A1018
ILE A1081
 None
 0.79A 2q83A-2p3vA:
undetectable		 2q83A-2p3vA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2p3v INOSITOL-1-MONOPHOSP
HATASE
(Thermotoga
maritima) 		4 / 6 ILE A1202
THR A1150
PHE A1156
PHE A1219
 None
 1.27A 3elzB-2p3vA:
undetectable		 3elzB-2p3vA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NV6_A_CAMA422_0
(CYTOCHROME P450)		 2p3v INOSITOL-1-MONOPHOSP
HATASE
(Thermotoga
maritima) 		3 / 3 GLY A1067
ILE A1049
VAL A1050
 None
 0.52A 3nv6A-2p3vA:
undetectable		 3nv6A-2p3vA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		 2p3v INOSITOL-1-MONOPHOSP
HATASE
(Thermotoga
maritima) 		4 / 7 THR A1194
GLY A1151
GLY A1083
THR A1084
 None
 0.84A 3tajA-2p3vA:
4.3		 3tajA-2p3vA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_C_08JC3_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2p3v INOSITOL-1-MONOPHOSP
HATASE
(Thermotoga
maritima) 		5 / 8 PRO A1080
VAL A1014
LEU A1011
LEU A1010
ILE A1078
 None
 1.48A 3u5kC-2p3vA:
undetectable		 3u5kC-2p3vA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U6T_A_KANA4699_1
(RIBOSOME
INACTIVATING PROTEIN)		 2p3v INOSITOL-1-MONOPHOSP
HATASE
(Thermotoga
maritima) 		5 / 10 ILE A1081
ASN A1027
ILE A1041
ALA A1045
GLU A1044
 None
 1.45A 3u6tA-2p3vA:
undetectable		 3u6tA-2p3vA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA804_1
(CATALASE-PEROXIDASE)		 2p3v INOSITOL-1-MONOPHOSP
HATASE
(Thermotoga
maritima) 		3 / 3 ASN A1027
GLU A1040
ARG A1043
 None
 0.96A 3wxoA-2p3vA:
undetectable		 3wxoA-2p3vA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2p3v INOSITOL-1-MONOPHOSP
HATASE
(Thermotoga
maritima) 		4 / 8 GLY A1015
VAL A1014
PHE A1094
ILE A1081
 None
 0.96A 4fglD-2p3vA:
2.1		 4fglD-2p3vA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_2
(TUBULIN BETA-2B
CHAIN)		 2p3v INOSITOL-1-MONOPHOSP
HATASE
(Thermotoga
maritima) 		5 / 12 LEU A1179
ALA A1113
ALA A1186
ILE A1208
ILE A1135
 None
 1.04A 4o2bB-2p3vA:
undetectable		 4o2bB-2p3vA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6V_E_RBFE201_1
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT B
NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT E)		 2p3v INOSITOL-1-MONOPHOSP
HATASE
(Thermotoga
maritima) 		4 / 5 VAL A1050
GLU A1052
VAL A1014
LYS A1013
 None
 1.19A 4p6vB-2p3vA:
undetectable
4p6vE-2p3vA:
1.8		 4p6vB-2p3vA:
21.86
4p6vE-2p3vA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2p3v INOSITOL-1-MONOPHOSP
HATASE
(Thermotoga
maritima) 		5 / 9 SER A1095
ALA A1113
MET A1019
LEU A1018
ILE A1049
 None
 1.48A 4xtaA-2p3vA:
undetectable		 4xtaA-2p3vA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_2
(TUBULIN BETA CHAIN)		 2p3v INOSITOL-1-MONOPHOSP
HATASE
(Thermotoga
maritima) 		5 / 12 LEU A1179
ALA A1113
ALA A1186
ILE A1208
ILE A1135
 None
 1.05A 5eypB-2p3vA:
undetectable		 5eypB-2p3vA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIO_B_LOCB502_1
(TUBULIN BETA CHAIN)		 2p3v INOSITOL-1-MONOPHOSP
HATASE
(Thermotoga
maritima) 		5 / 12 LEU A1179
ALA A1113
ALA A1186
ILE A1208
ILE A1135
 None
 1.06A 5mioB-2p3vA:
undetectable		 5mioB-2p3vA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NM5_B_LOCB502_2
(TUBULIN BETA-2B
CHAIN)		 2p3v INOSITOL-1-MONOPHOSP
HATASE
(Thermotoga
maritima) 		5 / 12 LEU A1179
ALA A1113
ALA A1186
ILE A1208
ILE A1135
 None
 0.91A 5nm5B-2p3vA:
undetectable		 5nm5B-2p3vA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWT_D_BEZD202_0
(PR 10 PROTEIN)		 2p3v INOSITOL-1-MONOPHOSP
HATASE
(Thermotoga
maritima) 		3 / 3 PHE A1006
ASP A1005
LYS A1009
 None
 0.85A 6awtD-2p3vA:
undetectable		 6awtD-2p3vA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		 2p3v INOSITOL-1-MONOPHOSP
HATASE
(Thermotoga
maritima) 		4 / 6 SER A1097
SER A1095
ALA A1181
ALA A1204
 None
 0.97A 6bocA-2p3vA:
undetectable
6bocB-2p3vA:
undetectable
6bocC-2p3vA:
undetectable
6bocD-2p3vA:
undetectable		 6bocA-2p3vA:
6.64
6bocB-2p3vA:
6.64
6bocC-2p3vA:
6.64
6bocD-2p3vA:
6.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		 2p3v INOSITOL-1-MONOPHOSP
HATASE
(Thermotoga
maritima) 		4 / 6 SER A1097
SER A1095
ALA A1182
ALA A1204
 None
 1.03A 6bocA-2p3vA:
undetectable
6bocB-2p3vA:
undetectable
6bocC-2p3vA:
undetectable
6bocD-2p3vA:
undetectable		 6bocA-2p3vA:
6.64
6bocB-2p3vA:
6.64
6bocC-2p3vA:
6.64
6bocD-2p3vA:
6.64