SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2p3w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_C_PXLC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)
2p3w PROBABLE SERINE
PROTEASE HTRA3

(Homo
sapiens)
4 / 8 ASP A 404
GLY A 405
VAL A 391
VAL A 436
None
0.82A 4c5nC-2p3wA:
undetectable
4c5nC-2p3wA:
15.22