SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2p4f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_B_ESTB354_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 2p4f SIMILAR TO SP|P32453
SACCHAROMYCES
CEREVISIAE YNL315C
ATP11
([Candida]
glabrata) 		4 / 8 SER A 242
VAL A 241
LEU A 249
VAL A 183
 None
 1.09A 1fduB-2p4fA:
undetectable		 1fduB-2p4fA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT3_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 2p4f SIMILAR TO SP|P32453
SACCHAROMYCES
CEREVISIAE YNL315C
ATP11
([Candida]
glabrata) 		4 / 7 LEU A 158
MET A 146
TYR A 257
LEU A 273
 None
 1.09A 1kt3A-2p4fA:
undetectable		 1kt3A-2p4fA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LCV_B_SAMB301_1
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)		 2p4f SIMILAR TO SP|P32453
SACCHAROMYCES
CEREVISIAE YNL315C
ATP11
([Candida]
glabrata) 		3 / 3 ARG A 162
ASP A 238
GLN A 234
 None
 0.93A 3lcvB-2p4fA:
undetectable		 3lcvB-2p4fA:
24.31