SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2p4u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT7_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 2p4u ACID PHOSPHATASE 1
(Mus
musculus) 		4 / 4 LEU A  30
ILE A 128
TYR A 120
TYR A 143
 None
 1.34A 3vt7A-2p4uA:
undetectable		 3vt7A-2p4uA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 2p4u ACID PHOSPHATASE 1
(Mus
musculus) 		3 / 3 SER A  44
ALA A  46
VAL A  47
 None
 0.61A 4x1iA-2p4uA:
undetectable		 4x1iA-2p4uA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 2p4u ACID PHOSPHATASE 1
(Mus
musculus) 		3 / 3 SER A  44
ALA A  46
VAL A  47
 None
 0.39A 4x20C-2p4uA:
undetectable		 4x20C-2p4uA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESE_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2p4u ACID PHOSPHATASE 1
(Mus
musculus) 		4 / 8 LEU A  90
PHE A  27
ILE A  42
PHE A 153
 None
 0.75A 5eseA-2p4uA:
undetectable		 5eseA-2p4uA:
15.47