SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2p58'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_B_SAMB1500_0
(ASPARTOKINASE)		 2p58 PUTATIVE TYPE III
SECRETION PROTEIN
YSCG
(Yersinia
pestis) 		4 / 7 SER C  89
ARG C  93
LEU C  94
GLU C  71
 None
 0.96A 2cdqB-2p58C:
undetectable		 2cdqB-2p58C:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL9_A_DR7A100_2
(PROTEASE)		 2p58 PUTATIVE TYPE III
SECRETION PROTEIN
YSCE
PUTATIVE TYPE III
SECRETION PROTEIN
YSCG
(Yersinia
pestis) 		5 / 10 ARG A  15
GLY A  63
ALA A  62
ILE C  15
ILE A  55
 None
 1.06A 3el9B-2p58A:
undetectable		 3el9B-2p58A:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ERD_B_DESB800_1
(ESTROGEN RECEPTOR
ALPHA)		 2p58 PUTATIVE TYPE III
SECRETION PROTEIN
YSCG
(Yersinia
pestis) 		5 / 10 MET C 109
GLU C  71
LEU C  59
LEU C  74
ARG C  93
 None
 1.49A 3erdB-2p58C:
undetectable		 3erdB-2p58C:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_1
(PROTEASE)		 2p58 PUTATIVE TYPE III
SECRETION PROTEIN
YSCE
PUTATIVE TYPE III
SECRETION PROTEIN
YSCF
PUTATIVE TYPE III
SECRETION PROTEIN
YSCG
(Yersinia
pestis) 		5 / 12 LEU C   9
ASP B  53
VAL A  61
ILE C  28
ILE C  12
 None
 0.90A 3s54A-2p58C:
undetectable		 3s54A-2p58C:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		 2p58 PUTATIVE TYPE III
SECRETION PROTEIN
YSCG
(Yersinia
pestis) 		4 / 6 GLY C  62
ASN C  63
LEU C  74
GLU C  39
 None
 0.87A 3zqtA-2p58C:
undetectable		 3zqtA-2p58C:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		 2p58 PUTATIVE TYPE III
SECRETION PROTEIN
YSCF
PUTATIVE TYPE III
SECRETION PROTEIN
YSCG
(Yersinia
pestis) 		4 / 7 ILE C 102
THR B  70
ILE B  71
SER B  74
 None
 0.71A 5fukA-2p58C:
undetectable
5fukB-2p58C:
undetectable		 5fukA-2p58C:
20.09
5fukB-2p58C:
20.09