SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2p5r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_A_CAMA502_0
(CYTOCHROME P450-CAM)		 2p5r GLUTATHIONE
PEROXIDASE 5
(Populus
trichocarpa
x
Populus
deltoides) 		4 / 6 PHE A  71
LEU A  35
VAL A  12
VAL A  25
 None
 1.14A 1dz4A-2p5rA:
undetectable		 1dz4A-2p5rA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_B_CAMB502_0
(CYTOCHROME P450-CAM)		 2p5r GLUTATHIONE
PEROXIDASE 5
(Populus
trichocarpa
x
Populus
deltoides) 		4 / 6 PHE A  71
LEU A  35
VAL A  12
VAL A  25
 None
 1.14A 1dz4B-2p5rA:
undetectable		 1dz4B-2p5rA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 2p5r GLUTATHIONE
PEROXIDASE 5
(Populus
trichocarpa
x
Populus
deltoides) 		4 / 5 PHE A  71
LEU A  35
VAL A  12
VAL A  25
 None
 1.15A 1t88B-2p5rA:
undetectable		 1t88B-2p5rA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2p5r GLUTATHIONE
PEROXIDASE 5
(Populus
trichocarpa
x
Populus
deltoides) 		5 / 9 PHE A 138
PHE A  71
VAL A  17
LEU A  27
LEU A  69
 None
 1.45A 1wrkA-2p5rA:
undetectable
1wrkB-2p5rA:
undetectable		 1wrkA-2p5rA:
18.02
1wrkB-2p5rA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M56_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 2p5r GLUTATHIONE
PEROXIDASE 5
(Populus
trichocarpa
x
Populus
deltoides) 		4 / 5 PHE A  71
LEU A  35
VAL A  12
VAL A  25
 None
 1.11A 2m56A-2p5rA:
undetectable		 2m56A-2p5rA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)		 2p5r GLUTATHIONE
PEROXIDASE 5
(Populus
trichocarpa
x
Populus
deltoides) 		4 / 6 PHE A  71
LEU A  35
VAL A  12
VAL A  25
 None
 1.10A 2zawA-2p5rA:
undetectable		 2zawA-2p5rA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VN2_A_TLSA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2p5r GLUTATHIONE
PEROXIDASE 5
(Populus
trichocarpa
x
Populus
deltoides) 		5 / 12 PHE A  99
ILE A 105
TYR A 116
LEU A 115
LEU A  35
 None
 1.12A 3vn2A-2p5rA:
undetectable		 3vn2A-2p5rA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_B_TYLB2198_1
(CREB-BINDING PROTEIN)		 2p5r GLUTATHIONE
PEROXIDASE 5
(Populus
trichocarpa
x
Populus
deltoides) 		4 / 5 VAL A  12
LEU A  35
ILE A  37
VAL A  17
 None
 0.97A 4a9kB-2p5rA:
undetectable		 4a9kB-2p5rA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 2p5r GLUTATHIONE
PEROXIDASE 5
(Populus
trichocarpa
x
Populus
deltoides) 		4 / 6 PHE A  71
LEU A  35
VAL A  12
VAL A  25
 None
 1.14A 4g3rB-2p5rA:
undetectable		 4g3rB-2p5rA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L49_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 2p5r GLUTATHIONE
PEROXIDASE 5
(Populus
trichocarpa
x
Populus
deltoides) 		4 / 5 PHE A  71
LEU A  35
VAL A  12
VAL A  25
 None
 1.14A 4l49A-2p5rA:
undetectable		 4l49A-2p5rA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_1
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 2p5r GLUTATHIONE
PEROXIDASE 5
(Populus
trichocarpa
x
Populus
deltoides) 		5 / 12 LEU A 115
LEU A 119
ILE A  37
GLY A 144
LEU A  27
 None
 1.02A 4lmnA-2p5rA:
undetectable		 4lmnA-2p5rA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA306_1
(CHITOSANASE)		 2p5r GLUTATHIONE
PEROXIDASE 5
(Populus
trichocarpa
x
Populus
deltoides) 		3 / 3 SER A   6
ASP A  14
GLN A 145
 None
 0.85A 4oltA-2p5rA:
undetectable
4oltB-2p5rA:
undetectable		 4oltA-2p5rA:
20.47
4oltB-2p5rA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB304_1
(CHITOSANASE)		 2p5r GLUTATHIONE
PEROXIDASE 5
(Populus
trichocarpa
x
Populus
deltoides) 		3 / 3 GLN A 145
SER A   6
ASP A  14
 None
 0.83A 4qwpA-2p5rA:
undetectable
4qwpB-2p5rA:
undetectable		 4qwpA-2p5rA:
20.47
4qwpB-2p5rA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2p5r GLUTATHIONE
PEROXIDASE 5
(Populus
trichocarpa
x
Populus
deltoides) 		4 / 6 ILE A  37
LEU A  69
PHE A  71
ARG A 117
 None
 0.99A 5b1aN-2p5rA:
undetectable
5b1aW-2p5rA:
undetectable		 5b1aN-2p5rA:
15.09
5b1aW-2p5rA:
19.85