SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2p62'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A7Q_A_CFBA328_2
(DEOXYCYTIDINE KINASE)		 2p62 HYPOTHETICAL PROTEIN
PH0156
(Pyrococcus
horikoshii) 		4 / 4 ILE A  39
ASP A  80
LEU A  87
ARG A  70
 None
 1.14A 2a7qA-2p62A:
3.4		 2a7qA-2p62A:
25.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X9G_A_LYAA1270_2
(PTERIDINE REDUCTASE)		 2p62 HYPOTHETICAL PROTEIN
PH0156
(Pyrococcus
horikoshii) 		3 / 3 MET A   1
VAL A  78
GLU A  91
 None
 0.86A 2x9gA-2p62A:
undetectable		 2x9gA-2p62A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_2
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2p62 HYPOTHETICAL PROTEIN
PH0156
(Pyrococcus
horikoshii) 		4 / 6 GLU A  66
ILE A   7
GLU A  90
VAL A  82
 None
 1.04A 4ejwB-2p62A:
undetectable		 4ejwB-2p62A:
26.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JQ1_B_NPSB401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 2p62 HYPOTHETICAL PROTEIN
PH0156
(Pyrococcus
horikoshii) 		4 / 8 VAL A  95
TYR A 134
ILE A  62
LEU A  20
 None
 0.91A 4jq1B-2p62A:
undetectable		 4jq1B-2p62A:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		 2p62 HYPOTHETICAL PROTEIN
PH0156
(Pyrococcus
horikoshii) 		3 / 3 THR A  12
SER A 205
TYR A 208
 None
 0.87A 5jsdA-2p62A:
undetectable		 5jsdA-2p62A:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		 2p62 HYPOTHETICAL PROTEIN
PH0156
(Pyrococcus
horikoshii) 		3 / 3 THR A  12
SER A 205
TYR A 208
 None
 0.89A 5jsdB-2p62A:
undetectable		 5jsdB-2p62A:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		 2p62 HYPOTHETICAL PROTEIN
PH0156
(Pyrococcus
horikoshii) 		3 / 3 THR A  12
SER A 205
TYR A 208
 None
 0.87A 5jsdC-2p62A:
undetectable		 5jsdC-2p62A:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		 2p62 HYPOTHETICAL PROTEIN
PH0156
(Pyrococcus
horikoshii) 		3 / 3 THR A  12
SER A 205
TYR A 208
 None
 0.88A 5jseB-2p62A:
undetectable		 5jseB-2p62A:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		 2p62 HYPOTHETICAL PROTEIN
PH0156
(Pyrococcus
horikoshii) 		3 / 3 THR A  12
SER A 205
TYR A 208
 None
 0.88A 5jseC-2p62A:
undetectable		 5jseC-2p62A:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_B_CXQB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 2p62 HYPOTHETICAL PROTEIN
PH0156
(Pyrococcus
horikoshii) 		4 / 6 VAL A 108
LEU A  75
LEU A  79
LEU A   5
 None
 0.98A 6f6sA-2p62A:
undetectable
6f6sB-2p62A:
undetectable		 6f6sA-2p62A:
15.88
6f6sB-2p62A:
14.23