SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2p65'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD507_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2p65 HYPOTHETICAL PROTEIN
PF08_0063
(Plasmodium
falciparum) 		4 / 7 PHE A 120
ALA A 158
ILE A  59
ILE A 181
 None
 0.93A 1oniD-2p65A:
undetectable
1oniF-2p65A:
undetectable		 1oniD-2p65A:
23.23
1oniF-2p65A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_A_SALA501_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 2p65 HYPOTHETICAL PROTEIN
PF08_0063
(Plasmodium
falciparum) 		5 / 9 GLY A 141
ALA A 140
LEU A 144
PHE A  99
LEU A  84
 None
 1.15A 1y7iA-2p65A:
undetectable		 1y7iA-2p65A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_C_H4BC1290_1
(PTERIDINE REDUCTASE
1)		 2p65 HYPOTHETICAL PROTEIN
PF08_0063
(Plasmodium
falciparum) 		4 / 8 PHE A  99
ASP A 139
LEU A 144
LEU A 107
 None
 0.93A 2bfpC-2p65A:
undetectable		 2bfpC-2p65A:
24.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_1
(CYTOCHROME P450 2C8)		 2p65 HYPOTHETICAL PROTEIN
PF08_0063
(Plasmodium
falciparum) 		5 / 12 SER A  39
SER A  75
ASN A  45
VAL A 118
VAL A  60
 None
 1.26A 2nniA-2p65A:
undetectable		 2nniA-2p65A:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_1
(THYROXINE-BINDING
GLOBULIN)		 2p65 HYPOTHETICAL PROTEIN
PF08_0063
(Plasmodium
falciparum) 		5 / 11 SER A  88
LEU A 107
LEU A 144
SER A  87
LEU A  86
 None
 0.91A 2xn5A-2p65A:
undetectable		 2xn5A-2p65A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YY8_B_SAMB500_0
(UPF0106 PROTEIN
PH0461)		 2p65 HYPOTHETICAL PROTEIN
PF08_0063
(Plasmodium
falciparum) 		5 / 11 LEU A  63
VAL A  60
ILE A  67
GLU A  61
ALA A  64
 None
 1.13A 2yy8A-2p65A:
undetectable
2yy8B-2p65A:
undetectable		 2yy8A-2p65A:
23.15
2yy8B-2p65A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTP_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 2p65 HYPOTHETICAL PROTEIN
PF08_0063
(Plasmodium
falciparum) 		5 / 12 GLY A 129
ALA A 130
ILE A 143
ASN A 142
GLN A 111
 None
 1.10A 4rtpA-2p65A:
undetectable		 4rtpA-2p65A:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)		 2p65 HYPOTHETICAL PROTEIN
PF08_0063
(Plasmodium
falciparum) 		5 / 10 SER A  88
LEU A 107
LEU A 144
SER A  87
LEU A  86
 None
 1.00A 4yiaA-2p65A:
undetectable		 4yiaA-2p65A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_A_0HKA1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 2p65 HYPOTHETICAL PROTEIN
PF08_0063
(Plasmodium
falciparum) 		3 / 3 ASN A  45
LEU A  76
PHE A 120
 None
 0.64A 5dsgA-2p65A:
undetectable		 5dsgA-2p65A:
18.31