SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2p6c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4002_1
(SERUM ALBUMIN)		 2p6c AQ_2013 PROTEIN
(Aquifex
aeolicus) 		4 / 4 ARG A  16
ALA A  89
ALA A  71
GLU A  68
 None
 1.23A 1e7bA-2p6cA:
undetectable		 1e7bA-2p6cA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4002_1
(SERUM ALBUMIN)		 2p6c AQ_2013 PROTEIN
(Aquifex
aeolicus) 		4 / 4 ARG A  16
ALA A  89
ALA A  71
GLU A  68
 None
 1.26A 1e7bB-2p6cA:
undetectable		 1e7bB-2p6cA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2p6c AQ_2013 PROTEIN
(Aquifex
aeolicus) 		5 / 10 ILE A 132
ILE A 134
VAL A  34
LYS A  35
GLY A 107
 None
 1.32A 3em0A-2p6cA:
undetectable		 3em0A-2p6cA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJB_A_198A1001_2
(ANDROGEN RECEPTOR)		 2p6c AQ_2013 PROTEIN
(Aquifex
aeolicus) 		4 / 7 LEU A  40
ILE A  21
ILE A 117
VAL A  25
 None
 0.68A 4ojbA-2p6cA:
undetectable		 4ojbA-2p6cA:
18.55