SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2p6v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2p6v TRANSCRIPTION
INITIATION FACTOR
TFIID SUBUNIT 4
(Homo
sapiens) 		4 / 8 LEU A 622
GLN A 624
PHE A 636
LEU A 640
 None
 0.96A 2eilP-2p6vA:
undetectable
2eilW-2p6vA:
undetectable		 2eilP-2p6vA:
18.34
2eilW-2p6vA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2p6v TRANSCRIPTION
INITIATION FACTOR
TFIID SUBUNIT 4
(Homo
sapiens) 		4 / 7 LEU A 622
GLN A 624
PHE A 636
LEU A 640
 None
 0.91A 5b1aC-2p6vA:
undetectable
5b1aJ-2p6vA:
undetectable		 5b1aC-2p6vA:
18.34
5b1aJ-2p6vA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2p6v TRANSCRIPTION
INITIATION FACTOR
TFIID SUBUNIT 4
(Homo
sapiens) 		4 / 7 LEU A 622
GLN A 624
PHE A 636
LEU A 640
 None
 0.89A 5b1aP-2p6vA:
undetectable
5b1aW-2p6vA:
undetectable		 5b1aP-2p6vA:
18.34
5b1aW-2p6vA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2p6v TRANSCRIPTION
INITIATION FACTOR
TFIID SUBUNIT 4
(Homo
sapiens) 		4 / 7 LEU A 622
GLN A 624
PHE A 636
LEU A 640
 None
 0.86A 5b3sC-2p6vA:
undetectable
5b3sJ-2p6vA:
undetectable		 5b3sC-2p6vA:
18.34
5b3sJ-2p6vA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 2p6v TRANSCRIPTION
INITIATION FACTOR
TFIID SUBUNIT 4
(Homo
sapiens) 		4 / 7 LEU A 622
GLN A 624
PHE A 636
LEU A 640
 None
 0.87A 5b3sP-2p6vA:
undetectable		 5b3sP-2p6vA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2p6v TRANSCRIPTION
INITIATION FACTOR
TFIID SUBUNIT 4
(Homo
sapiens) 		4 / 7 LEU A 622
GLN A 624
PHE A 636
LEU A 640
 None
 0.87A 5iy5C-2p6vA:
undetectable
5iy5J-2p6vA:
undetectable		 5iy5C-2p6vA:
17.54
5iy5J-2p6vA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2p6v TRANSCRIPTION
INITIATION FACTOR
TFIID SUBUNIT 4
(Homo
sapiens) 		4 / 7 LEU A 622
GLN A 624
PHE A 636
LEU A 640
 None
 0.86A 5z84C-2p6vA:
undetectable
5z84J-2p6vA:
undetectable		 5z84C-2p6vA:
18.34
5z84J-2p6vA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_A_BEZA502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 2p6v TRANSCRIPTION
INITIATION FACTOR
TFIID SUBUNIT 4
(Homo
sapiens) 		4 / 6 VAL A 623
LEU A 660
LEU A 663
ARG A 664
 MLY  A 620 ( 4.1A)
None
MLY  A 596 ( 4.4A)
None
 1.00A 6e43A-2p6vA:
undetectable		 6e43A-2p6vA:
14.58