SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2p6y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_B_SAMB202_0
(UPF0066 PROTEIN
AF_0241)		 2p6y HYPOTHETICAL PROTEIN
VCA0587
(Vibrio
cholerae) 		5 / 12 GLN A 111
ALA A 131
PRO A 110
GLY A  31
LEU A  69
 None
 1.35A 2nv4B-2p6yA:
undetectable		 2nv4B-2p6yA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUB_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2p6y HYPOTHETICAL PROTEIN
VCA0587
(Vibrio
cholerae) 		3 / 3 TYR A 124
ARG A 116
HIS A  75
 None
None
ZN  A 201 (-3.3A)
 0.94A 4fubA-2p6yA:
undetectable		 4fubA-2p6yA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 2p6y HYPOTHETICAL PROTEIN
VCA0587
(Vibrio
cholerae) 		3 / 3 THR A 122
GLU A 126
HIS A  75
 None
None
ZN  A 201 (-3.3A)
 0.91A 5xiqD-2p6yA:
undetectable		 5xiqD-2p6yA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_2
(CARBONIC ANHYDRASE 2)		 2p6y HYPOTHETICAL PROTEIN
VCA0587
(Vibrio
cholerae) 		4 / 5 HIS A 107
HIS A 112
LEU A 127
VAL A 129
 None
 1.09A 6bc9A-2p6yA:
undetectable		 6bc9A-2p6yA:
18.52