SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2p7j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_2
(PROTEASE)		 2p7j PUTATIVE SENSORY
BOX/GGDEF FAMILY
PROTEIN
(Vibrio
parahaemolyticus) 		5 / 9 VAL A 193
GLY A 210
ILE A 213
ALA A 201
ILE A 200
 None
 1.04A 3el0B-2p7jA:
undetectable		 3el0B-2p7jA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q1E_D_T44D328_1
(5-HYDROXYISOURATE
HYDROLASE)		 2p7j PUTATIVE SENSORY
BOX/GGDEF FAMILY
PROTEIN
(Vibrio
parahaemolyticus) 		5 / 9 LEU A  22
LEU A  19
THR A  14
LEU A 266
LEU A 246
 None
 1.17A 3q1eB-2p7jA:
undetectable
3q1eD-2p7jA:
undetectable		 3q1eB-2p7jA:
18.28
3q1eD-2p7jA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_2
(SEPIAPTERIN
REDUCTASE)		 2p7j PUTATIVE SENSORY
BOX/GGDEF FAMILY
PROTEIN
(Vibrio
parahaemolyticus) 		3 / 3 LEU A 167
MET A 155
ASP A 172
 None
 0.74A 4j7xB-2p7jA:
undetectable		 4j7xB-2p7jA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTP_A_ASCA802_0
(RRNA N-GLYCOSIDASE)		 2p7j PUTATIVE SENSORY
BOX/GGDEF FAMILY
PROTEIN
(Vibrio
parahaemolyticus) 		4 / 5 TYR A  96
ILE A  94
ASN A  74
ILE A  81
 None
 1.06A 4jtpA-2p7jA:
undetectable		 4jtpA-2p7jA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5I_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 2p7j PUTATIVE SENSORY
BOX/GGDEF FAMILY
PROTEIN
(Vibrio
parahaemolyticus) 		3 / 3 ASP A 172
ARG A 115
ARG A  82
 None
SO4  A 501 (-2.6A)
SO4  A 501 (-3.2A)
 0.97A 4x5iA-2p7jA:
undetectable		 4x5iA-2p7jA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA306_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 2p7j PUTATIVE SENSORY
BOX/GGDEF FAMILY
PROTEIN
(Vibrio
parahaemolyticus) 		4 / 7 ARG A  82
PHE A  83
LEU A  49
SER A 158
 SO4  A 501 (-3.2A)
None
None
None
 1.06A 5uxcA-2p7jA:
undetectable		 5uxcA-2p7jA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_G_ZOLG401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 2p7j PUTATIVE SENSORY
BOX/GGDEF FAMILY
PROTEIN
(Vibrio
parahaemolyticus) 		4 / 7 ASP A 139
ARG A 115
GLN A  80
LYS A  79
 None
SO4  A 501 (-2.6A)
SO4  A 501 (-3.5A)
None
 1.17A 6g31G-2p7jA:
undetectable		 6g31G-2p7jA:
14.56