SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2p7k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SGL_A_SAMA692_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 2p7k GLYOXALASE FAMILY
PROTEIN
(Listeria
monocytogenes) 		5 / 12 GLY A 104
GLY A 122
THR A 123
LEU A 124
GLY A 102
 None
 1.04A 3sglA-2p7kA:
undetectable		 3sglA-2p7kA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_2
(CDL2.3B)		 2p7k GLYOXALASE FAMILY
PROTEIN
(Listeria
monocytogenes) 		5 / 9 ILE A  25
VAL A  12
LEU A  10
ILE A  56
LEU A 119
 None
 1.41A 5iepA-2p7kA:
undetectable		 5iepA-2p7kA:
21.88