SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2p7n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_A_CTXA1_1
(CES1 PROTEIN)		 2p7n PATHOGENICITY ISLAND
1 EFFECTOR PROTEIN
(Chromobacterium
violaceum) 		5 / 12 ALA A 153
GLY A 161
LEU A 374
SER A 373
LEU A 378
 None
 1.01A 1ya4A-2p7nA:
undetectable		 1ya4A-2p7nA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 2p7n PATHOGENICITY ISLAND
1 EFFECTOR PROTEIN
(Chromobacterium
violaceum) 		3 / 3 GLY A 198
GLU A 201
ASP A 194
 None
 0.55A 2b25B-2p7nA:
undetectable		 2b25B-2p7nA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B9E_A_SAMA1201_0
(NOL1/NOP2/SUN DOMAIN
FAMILY, MEMBER 5
ISOFORM 2)		 2p7n PATHOGENICITY ISLAND
1 EFFECTOR PROTEIN
(Chromobacterium
violaceum) 		5 / 12 GLY A 277
ASN A 310
LEU A 292
ASP A 316
PHE A 300
 None
 1.09A 2b9eA-2p7nA:
undetectable		 2b9eA-2p7nA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC59_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 2p7n PATHOGENICITY ISLAND
1 EFFECTOR PROTEIN
(Chromobacterium
violaceum) 		3 / 3 GLY A 328
GLY A 333
GLY A 331
 None
 0.41A 3bogC-2p7nA:
undetectable		 3bogC-2p7nA:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2O_C_AG2C1002_1
(BIOSYNTHETIC
ARGININE
DECARBOXYLASE)		 2p7n PATHOGENICITY ISLAND
1 EFFECTOR PROTEIN
(Chromobacterium
violaceum) 		4 / 8 SER A 135
LEU A  49
TRP A 182
ASP A 178
 None
 1.17A 3n2oC-2p7nA:
undetectable
3n2oD-2p7nA:
undetectable		 3n2oC-2p7nA:
21.87
3n2oD-2p7nA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_B_BEZB264_0
(ECHA1_1)		 2p7n PATHOGENICITY ISLAND
1 EFFECTOR PROTEIN
(Chromobacterium
violaceum) 		4 / 7 ILE A 185
LEU A 142
ALA A 171
ALA A 172
 None
 0.89A 3r9tB-2p7nA:
undetectable		 3r9tB-2p7nA:
22.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R9V_B_DXCB323_0
(INVASIN IPAD)		 2p7n PATHOGENICITY ISLAND
1 EFFECTOR PROTEIN
(Chromobacterium
violaceum) 		4 / 7 ILE A 185
ILE A 189
VAL A 379
LEU A 382
 None
 0.65A 3r9vA-2p7nA:
12.2
3r9vB-2p7nA:
13.3		 3r9vA-2p7nA:
34.77
3r9vB-2p7nA:
34.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_A_DXCA91_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2p7n PATHOGENICITY ISLAND
1 EFFECTOR PROTEIN
(Chromobacterium
violaceum) 		3 / 3 PHE A 214
GLN A 362
PHE A 350
 None
 0.82A 3rv5A-2p7nA:
0.4		 3rv5A-2p7nA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_A_MRVA1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 2p7n PATHOGENICITY ISLAND
1 EFFECTOR PROTEIN
(Chromobacterium
violaceum) 		4 / 7 GLN A  73
THR A  74
LEU A 361
THR A 365
 None
 1.12A 4mbsA-2p7nA:
3.6		 4mbsA-2p7nA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM5_A_SREA603_1
(TRANSPORTER)		 2p7n PATHOGENICITY ISLAND
1 EFFECTOR PROTEIN
(Chromobacterium
violaceum) 		5 / 9 ASP A 259
PRO A 267
VAL A 264
GLY A 274
GLY A 277
 None
 1.23A 4mm5A-2p7nA:
undetectable		 4mm5A-2p7nA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMB_A_SREA603_1
(TRANSPORTER)		 2p7n PATHOGENICITY ISLAND
1 EFFECTOR PROTEIN
(Chromobacterium
violaceum) 		5 / 9 ASP A 259
PRO A 267
VAL A 264
GLY A 274
GLY A 277
 None
 1.29A 4mmbA-2p7nA:
undetectable		 4mmbA-2p7nA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_A_29EA603_1
(TRANSPORTER)		 2p7n PATHOGENICITY ISLAND
1 EFFECTOR PROTEIN
(Chromobacterium
violaceum) 		5 / 10 ASP A 259
PRO A 267
VAL A 264
GLY A 274
GLY A 277
 None
 1.20A 4mmdA-2p7nA:
undetectable		 4mmdA-2p7nA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWZ_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 2p7n PATHOGENICITY ISLAND
1 EFFECTOR PROTEIN
(Chromobacterium
violaceum) 		3 / 3 MET A 221
GLN A 220
ARG A  84
 None
 1.08A 5ewzB-2p7nA:
undetectable		 5ewzB-2p7nA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		 2p7n PATHOGENICITY ISLAND
1 EFFECTOR PROTEIN
(Chromobacterium
violaceum) 		4 / 6 ASN A 370
ALA A 371
PRO A 154
TYR A 200
 None
 1.09A 5umd2-2p7nA:
undetectable
5umdF-2p7nA:
undetectable		 5umd2-2p7nA:
10.81
5umdF-2p7nA:
10.98