SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2p84'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KF6_B_ACTB704_0
(FUMARATE REDUCTASE
FLAVOPROTEIN
FUMARATE REDUCTASE
IRON-SULFUR PROTEIN)		 2p84 ORF041
(Staphylococcus
virus
37) 		3 / 3 ARG A   8
GLY A 120
ASP A  76
 None
 0.43A 1kf6A-2p84A:
undetectable
1kf6B-2p84A:
undetectable		 1kf6A-2p84A:
13.51
1kf6B-2p84A:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		 2p84 ORF041
(Staphylococcus
virus
37) 		4 / 5 ASP A 106
GLU A  99
GLY A 104
GLU A  89
 None
 1.30A 3w9tA-2p84A:
undetectable		 3w9tA-2p84A:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		 2p84 ORF041
(Staphylococcus
virus
37) 		4 / 5 ASP A 106
GLU A  99
GLY A 104
GLU A  89
 None
 1.31A 3w9tC-2p84A:
undetectable		 3w9tC-2p84A:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		 2p84 ORF041
(Staphylococcus
virus
37) 		4 / 5 ASP A 106
GLU A  99
GLY A 104
GLU A  89
 None
 1.31A 3w9tD-2p84A:
undetectable		 3w9tD-2p84A:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		 2p84 ORF041
(Staphylococcus
virus
37) 		4 / 5 ASP A 106
GLU A  99
GLY A 104
GLU A  89
 None
 1.29A 3w9tG-2p84A:
undetectable		 3w9tG-2p84A:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_B_GLYB709_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 2p84 ORF041
(Staphylococcus
virus
37) 		4 / 5 GLY A 120
ASN A 121
ASP A  76
ARG A   8
 None
 1.00A 6dwdB-2p84A:
undetectable
6dwdD-2p84A:
undetectable		 6dwdB-2p84A:
12.80
6dwdD-2p84A:
12.80