SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2p90'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVT_A_FLPA125_1
(TRANSTHYRETIN)		 2p90 HYPOTHETICAL PROTEIN
CGL1923
(Corynebacterium
glutamicum) 		4 / 8 ALA A  36
LEU A  93
LEU A 107
THR A 135
 None
 0.96A 1dvtA-2p90A:
undetectable
1dvtB-2p90A:
undetectable		 1dvtA-2p90A:
18.37
1dvtB-2p90A:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_C_ACTC36_0
(GCN4 LEUCINE ZIPPER)		 2p90 HYPOTHETICAL PROTEIN
CGL1923
(Corynebacterium
glutamicum) 		5 / 10 SER A 206
TYR A 210
HIS A  40
ALA A 213
ALA A  41
 None
 1.42A 2r2vC-2p90A:
undetectable
2r2vF-2p90A:
undetectable
2r2vG-2p90A:
undetectable		 2r2vC-2p90A:
7.52
2r2vF-2p90A:
7.52
2r2vG-2p90A:
7.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_C_ACTC36_0
(GCN4 LEUCINE ZIPPER)		 2p90 HYPOTHETICAL PROTEIN
CGL1923
(Corynebacterium
glutamicum) 		5 / 10 SER A 206
TYR A 210
HIS A  40
ALA A 213
ALA A 140
 None
 1.38A 2r2vC-2p90A:
undetectable
2r2vF-2p90A:
undetectable
2r2vG-2p90A:
undetectable		 2r2vC-2p90A:
7.52
2r2vF-2p90A:
7.52
2r2vG-2p90A:
7.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_D_ASDD1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2p90 HYPOTHETICAL PROTEIN
CGL1923
(Corynebacterium
glutamicum) 		5 / 9 PRO A 110
LEU A  91
LEU A  32
ALA A 179
PHE A 119
 None
 1.20A 2vcvD-2p90A:
undetectable		 2vcvD-2p90A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_E_ASDE1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2p90 HYPOTHETICAL PROTEIN
CGL1923
(Corynebacterium
glutamicum) 		5 / 9 PRO A 110
LEU A  91
LEU A  32
ALA A 179
PHE A 119
 None
 1.21A 2vcvE-2p90A:
undetectable		 2vcvE-2p90A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_H_ASDH1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2p90 HYPOTHETICAL PROTEIN
CGL1923
(Corynebacterium
glutamicum) 		5 / 9 PRO A 110
LEU A  91
LEU A  32
ALA A 179
PHE A 119
 None
 1.23A 2vcvH-2p90A:
undetectable		 2vcvH-2p90A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA358_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 2p90 HYPOTHETICAL PROTEIN
CGL1923
(Corynebacterium
glutamicum) 		3 / 3 HIS A 242
HIS A 147
MET A 246
 None
 0.98A 3mihA-2p90A:
undetectable		 3mihA-2p90A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q1E_D_T44D328_1
(5-HYDROXYISOURATE
HYDROLASE)		 2p90 HYPOTHETICAL PROTEIN
CGL1923
(Corynebacterium
glutamicum) 		5 / 9 LEU A  93
LEU A 107
THR A 135
LEU A 187
LEU A 183
 None
 1.29A 3q1eB-2p90A:
undetectable
3q1eD-2p90A:
undetectable		 3q1eB-2p90A:
17.04
3q1eD-2p90A:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2p90 HYPOTHETICAL PROTEIN
CGL1923
(Corynebacterium
glutamicum) 		4 / 8 ILE A  58
LEU A  93
VAL A 132
GLY A 131
 None
 0.88A 3w1wA-2p90A:
2.4		 3w1wA-2p90A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_1
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 2p90 HYPOTHETICAL PROTEIN
CGL1923
(Corynebacterium
glutamicum) 		3 / 3 SER A 195
TYR A 197
ASP A 161
 None
 0.88A 4rp8C-2p90A:
undetectable		 4rp8C-2p90A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZO1_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 2p90 HYPOTHETICAL PROTEIN
CGL1923
(Corynebacterium
glutamicum) 		5 / 12 ILE A  29
ALA A  31
ALA A  41
LEU A 217
PHE A 104
 None
 1.49A 4zo1X-2p90A:
undetectable		 4zo1X-2p90A:
21.02