SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2p97'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2p97 HYPOTHETICAL PROTEIN
(Trichormus
variabilis) 		4 / 8 ALA A  70
THR A  77
THR A  79
ILE A  81
 None
 0.81A 1gtnA-2p97A:
undetectable
1gtnB-2p97A:
undetectable		 1gtnA-2p97A:
18.13
1gtnB-2p97A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2p97 HYPOTHETICAL PROTEIN
(Trichormus
variabilis) 		4 / 8 ALA A  70
THR A  77
THR A  79
ILE A  81
 None
 0.81A 1gtnP-2p97A:
undetectable
1gtnQ-2p97A:
undetectable		 1gtnP-2p97A:
18.13
1gtnQ-2p97A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KF6_B_ACTB704_0
(FUMARATE REDUCTASE
FLAVOPROTEIN
FUMARATE REDUCTASE
IRON-SULFUR PROTEIN)		 2p97 HYPOTHETICAL PROTEIN
(Trichormus
variabilis) 		3 / 3 ARG A 166
GLY A 102
ASP A 101
 None
 0.52A 1kf6A-2p97A:
undetectable
1kf6B-2p97A:
undetectable		 1kf6A-2p97A:
17.05
1kf6B-2p97A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA502_1
(YKOF)		 2p97 HYPOTHETICAL PROTEIN
(Trichormus
variabilis) 		4 / 6 ALA A 175
LEU A 132
ILE A 133
SER A 183
 None
 0.98A 1sbrA-2p97A:
undetectable
1sbrB-2p97A:
undetectable		 1sbrA-2p97A:
22.07
1sbrB-2p97A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_B_TRPB81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2p97 HYPOTHETICAL PROTEIN
(Trichormus
variabilis) 		4 / 8 ALA A  70
THR A  77
THR A  79
ILE A  81
 None
 0.75A 1utdB-2p97A:
undetectable
1utdC-2p97A:
undetectable		 1utdB-2p97A:
18.13
1utdC-2p97A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_F_TRPF81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2p97 HYPOTHETICAL PROTEIN
(Trichormus
variabilis) 		4 / 8 ALA A  70
THR A  77
THR A  79
ILE A  81
 None
 0.74A 1utdF-2p97A:
undetectable
1utdG-2p97A:
undetectable		 1utdF-2p97A:
18.13
1utdG-2p97A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_J_TRPJ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2p97 HYPOTHETICAL PROTEIN
(Trichormus
variabilis) 		4 / 8 ALA A  70
THR A  77
THR A  79
ILE A  81
 None
 0.74A 1utdJ-2p97A:
undetectable
1utdK-2p97A:
undetectable		 1utdJ-2p97A:
18.13
1utdK-2p97A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OA1_B_ADNB2005_1
(TRYPTOPHAN
HALOGENASE)		 2p97 HYPOTHETICAL PROTEIN
(Trichormus
variabilis) 		4 / 7 GLY A 145
GLY A 144
VAL A 138
LEU A 195
 None
 0.80A 2oa1B-2p97A:
undetectable		 2oa1B-2p97A:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELU_A_SAMA4633_0
(METHYLTRANSFERASE)		 2p97 HYPOTHETICAL PROTEIN
(Trichormus
variabilis) 		5 / 12 GLY A 181
GLY A 179
GLY A  25
ASP A  22
ILE A  21
 None
 1.06A 3eluA-2p97A:
undetectable		 3eluA-2p97A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCZ_A_SAMA4633_0
(POLYPROTEIN)		 2p97 HYPOTHETICAL PROTEIN
(Trichormus
variabilis) 		5 / 12 GLY A 181
GLY A 179
GLY A  25
ASP A  22
ILE A  21
 None
 1.05A 3gczA-2p97A:
undetectable		 3gczA-2p97A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDA_A_DEXA1985_2
(MINERALOCORTICOID
RECEPTOR)		 2p97 HYPOTHETICAL PROTEIN
(Trichormus
variabilis) 		4 / 6 LEU A 195
LEU A 149
THR A 134
VAL A 176
 None
 1.06A 4udaA-2p97A:
undetectable		 4udaA-2p97A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEI_A_SHHA2004_1
(HDAC6 PROTEIN)		 2p97 HYPOTHETICAL PROTEIN
(Trichormus
variabilis) 		5 / 12 SER A  11
HIS A  66
GLY A  25
PHE A  26
ASP A 136
 None
MG  A 201 (-3.4A)
None
None
MG  A 201 (-2.4A)
 1.31A 5eeiA-2p97A:
undetectable		 5eeiA-2p97A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEI_B_SHHB801_1
(HDAC6 PROTEIN)		 2p97 HYPOTHETICAL PROTEIN
(Trichormus
variabilis) 		5 / 12 SER A  11
HIS A  66
GLY A  25
PHE A  26
ASP A 136
 None
MG  A 201 (-3.4A)
None
None
MG  A 201 (-2.4A)
 1.30A 5eeiB-2p97A:
undetectable		 5eeiB-2p97A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_C_SAMC4000_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 2p97 HYPOTHETICAL PROTEIN
(Trichormus
variabilis) 		5 / 12 GLY A 181
GLY A 179
GLY A  25
ASP A  22
ILE A  21
 None
 1.06A 5ehiC-2p97A:
undetectable		 5ehiC-2p97A:
21.58