SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2p9b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A29_A_TFPA154_1
(CALMODULIN)		 2p9b POSSIBLE PROLIDASE
(Bifidobacterium
longum) 		5 / 10 GLU A 361
ALA A 416
LEU A 406
LEU A  73
GLU A 359
 None
 1.28A 1a29A-2p9bA:
undetectable		 1a29A-2p9bA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 2p9b POSSIBLE PROLIDASE
(Bifidobacterium
longum) 		5 / 12 PHE A  14
VAL A  69
VAL A  38
ALA A 401
ILE A  44
 None
 0.99A 1epbB-2p9bA:
undetectable		 1epbB-2p9bA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FWE_C_HAEC989_1
(UREASE)		 2p9b POSSIBLE PROLIDASE
(Bifidobacterium
longum) 		5 / 6 HIS A  77
HIS A  79
HIS A 246
HIS A 266
ASP A 345
 None
 0.95A 1fweC-2p9bA:
20.4		 1fweC-2p9bA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		 2p9b POSSIBLE PROLIDASE
(Bifidobacterium
longum) 		5 / 11 ALA A 190
VAL A 243
ALA A 245
ALA A 206
LEU A 179
 None
 0.99A 1jinA-2p9bA:
undetectable		 1jinA-2p9bA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEI_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 2p9b POSSIBLE PROLIDASE
(Bifidobacterium
longum) 		4 / 8 SER A 225
ILE A 168
GLU A 251
GLY A 252
 None
 0.95A 1meiA-2p9bA:
5.2		 1meiA-2p9bA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RL8_A_RITA9001_2
(PROTEASE RETROPEPSIN)		 2p9b POSSIBLE PROLIDASE
(Bifidobacterium
longum) 		6 / 12 ARG A 279
LEU A 338
GLY A 329
ALA A 330
GLY A 368
ILE A 340
 None
 1.33A 1rl8B-2p9bA:
undetectable		 1rl8B-2p9bA:
11.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA502_1
(YKOF)		 2p9b POSSIBLE PROLIDASE
(Bifidobacterium
longum) 		4 / 6 PHE A  14
ALA A  15
LEU A  16
ILE A  36
 None
 0.86A 1sbrA-2p9bA:
undetectable
1sbrB-2p9bA:
undetectable		 1sbrA-2p9bA:
19.26
1sbrB-2p9bA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_A_SALA506_1
(SALICYLATE
SYNTHETASE, IRP9)		 2p9b POSSIBLE PROLIDASE
(Bifidobacterium
longum) 		5 / 11 ILE A 385
GLY A 343
THR A 294
HIS A  77
GLY A 341
 None
 1.16A 2fn1A-2p9bA:
undetectable		 2fn1A-2p9bA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_B_SALB503_1
(SALICYLATE
SYNTHETASE, IRP9)		 2p9b POSSIBLE PROLIDASE
(Bifidobacterium
longum) 		5 / 11 ILE A 385
GLY A 343
THR A 294
HIS A  77
GLY A 341
 None
 1.14A 2fn1B-2p9bA:
undetectable		 2fn1B-2p9bA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_B_SAMB270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 2p9b POSSIBLE PROLIDASE
(Bifidobacterium
longum) 		5 / 11 ALA A 205
GLY A 267
ILE A 204
VAL A 253
SER A 256
 None
 1.09A 3gyqB-2p9bA:
undetectable		 3gyqB-2p9bA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2p9b POSSIBLE PROLIDASE
(Bifidobacterium
longum) 		5 / 12 LEU A 403
PHE A  14
GLY A  42
ALA A 426
SER A 400
 None
 1.22A 3n8xA-2p9bA:
undetectable		 3n8xA-2p9bA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_C_BEZC264_0
(ECHA1_1)		 2p9b POSSIBLE PROLIDASE
(Bifidobacterium
longum) 		4 / 5 ALA A 190
GLU A 186
ALA A 178
MET A 224
 None
 1.15A 3r9tC-2p9bA:
undetectable		 3r9tC-2p9bA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_3
(PROTEASE)		 2p9b POSSIBLE PROLIDASE
(Bifidobacterium
longum) 		6 / 12 ARG A 279
LEU A 338
GLY A 329
ALA A 330
GLY A 368
ILE A 340
 None
 1.38A 3tl9B-2p9bA:
undetectable		 3tl9B-2p9bA:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 2p9b POSSIBLE PROLIDASE
(Bifidobacterium
longum) 		5 / 12 ALA A 259
VAL A 261
THR A 207
ILE A 264
SER A 268
 None
 1.21A 4c49A-2p9bA:
undetectable		 4c49A-2p9bA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA501_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 2p9b POSSIBLE PROLIDASE
(Bifidobacterium
longum) 		4 / 5 TYR A 366
LEU A 362
TYR A 449
LEU A 303
 None
 1.25A 4em2A-2p9bA:
0.0		 4em2A-2p9bA:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H9M_A_HAEA929_1
(UREASE)		 2p9b POSSIBLE PROLIDASE
(Bifidobacterium
longum) 		4 / 5 HIS A  77
HIS A 246
HIS A 266
ASP A 345
 None
 0.96A 4h9mA-2p9bA:
21.3		 4h9mA-2p9bA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA601_1
(SERUM ALBUMIN)		 2p9b POSSIBLE PROLIDASE
(Bifidobacterium
longum) 		5 / 12 LEU A 274
VAL A 261
GLY A 260
SER A 289
SER A 268
 None
 1.33A 4ot2A-2p9bA:
undetectable		 4ot2A-2p9bA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA301_1
(CHITOSANASE)		 2p9b POSSIBLE PROLIDASE
(Bifidobacterium
longum) 		3 / 3 TYR A 140
GLY A 163
PRO A 164
 None
 0.67A 4qwpA-2p9bA:
undetectable		 4qwpA-2p9bA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBP_C_HAEC800_1
(PROTEIN (UREASE
(CHAIN C)))		 2p9b POSSIBLE PROLIDASE
(Bifidobacterium
longum) 		5 / 6 HIS A  77
HIS A  79
HIS A 246
HIS A 266
ASP A 345
 None
 0.91A 4ubpC-2p9bA:
19.6		 4ubpC-2p9bA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2p9b POSSIBLE PROLIDASE
(Bifidobacterium
longum) 		5 / 12 TYR A 449
VAL A 342
GLY A 209
THR A 211
LEU A 301
 None
 1.40A 5esgA-2p9bA:
undetectable		 5esgA-2p9bA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_A_BEZA1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 2p9b POSSIBLE PROLIDASE
(Bifidobacterium
longum) 		4 / 6 GLY A 252
SER A 256
VAL A 253
HIS A 246
 None
 1.13A 5ewuA-2p9bA:
undetectable		 5ewuA-2p9bA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)		 2p9b POSSIBLE PROLIDASE
(Bifidobacterium
longum) 		5 / 11 SER A 296
THR A 344
GLU A 359
TYR A 449
LEU A 303
 None
 1.47A 5jh7B-2p9bA:
undetectable		 5jh7B-2p9bA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQB_B_IBPB706_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 2p9b POSSIBLE PROLIDASE
(Bifidobacterium
longum) 		4 / 8 ALA A 416
LEU A 360
LEU A 404
LEU A  73
 None
 0.68A 5jqbA-2p9bA:
undetectable
5jqbB-2p9bA:
0.3		 5jqbA-2p9bA:
21.72
5jqbB-2p9bA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KM8_B_L8PB201_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 2,
MITOCHONDRIAL)		 2p9b POSSIBLE PROLIDASE
(Bifidobacterium
longum) 		4 / 8 GLN A 248
ALA A 245
HIS A  77
HIS A 266
 None
 1.16A 5km8A-2p9bA:
undetectable
5km8B-2p9bA:
undetectable		 5km8A-2p9bA:
16.17
5km8B-2p9bA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 2p9b POSSIBLE PROLIDASE
(Bifidobacterium
longum) 		5 / 12 LEU A 338
LEU A 291
GLY A 329
VAL A 269
LEU A 257
 None
 1.17A 5uc1A-2p9bA:
undetectable		 5uc1A-2p9bA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_2
(GLUCOCORTICOID
RECEPTOR)		 2p9b POSSIBLE PROLIDASE
(Bifidobacterium
longum) 		5 / 12 LEU A 338
LEU A 291
GLY A 329
VAL A 269
LEU A 257
 None
 1.15A 5uc1B-2p9bA:
undetectable		 5uc1B-2p9bA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2p9b POSSIBLE PROLIDASE
(Bifidobacterium
longum) 		5 / 12 ILE A  21
ILE A  55
TYR A  61
ILE A  44
HIS A  18
 None
 1.22A 5y2tB-2p9bA:
undetectable		 5y2tB-2p9bA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_1
(HIV-1 PROTEASE)		 2p9b POSSIBLE PROLIDASE
(Bifidobacterium
longum) 		6 / 12 ARG A 279
LEU A 338
GLY A 329
ALA A 330
GLY A 368
ILE A 340
 None
 1.40A 6dilB-2p9bA:
undetectable		 6dilB-2p9bA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 2p9b POSSIBLE PROLIDASE
(Bifidobacterium
longum) 		4 / 5 ARG A 358
ALA A 355
TYR A 354
ILE A 441
 None
 1.47A 6g9bA-2p9bA:
undetectable
6g9bB-2p9bA:
undetectable		 6g9bA-2p9bA:
12.47
6g9bB-2p9bA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_H_PCFH604_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 2p9b POSSIBLE PROLIDASE
(Bifidobacterium
longum) 		4 / 8 GLY A 209
HIS A 266
GLY A 252
SER A 249
 None
 0.80A 6hu9H-2p9bA:
undetectable
6hu9e-2p9bA:
undetectable		 6hu9H-2p9bA:
9.61
6hu9e-2p9bA:
15.80