SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2p9m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YZQ_A_SAMA6075_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN PH1780)		 2p9m HYPOTHETICAL PROTEIN
MJ0922
(Methanocaldococc
us
jannaschii) 		5 / 12 ILE A  54
ILE A  84
ILE A 109
GLN A 111
PRO A 113
 None
 0.87A 2yzqA-2p9mA:
13.6		 2yzqA-2p9mA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YZQ_A_SAMA6075_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN PH1780)		 2p9m HYPOTHETICAL PROTEIN
MJ0922
(Methanocaldococc
us
jannaschii) 		6 / 12 ILE A  54
THR A  58
VAL A  83
ILE A  84
ILE A 109
PRO A 113
 None
 0.95A 2yzqA-2p9mA:
13.6		 2yzqA-2p9mA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YZQ_A_SAMA6075_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN PH1780)		 2p9m HYPOTHETICAL PROTEIN
MJ0922
(Methanocaldococc
us
jannaschii) 		5 / 12 ILE A 124
THR A  15
VAL A  18
GLN A 111
PRO A  43
 None
 1.12A 2yzqA-2p9mA:
13.6		 2yzqA-2p9mA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YZQ_A_SAMA6075_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN PH1780)		 2p9m HYPOTHETICAL PROTEIN
MJ0922
(Methanocaldococc
us
jannaschii) 		6 / 12 ILE A 124
THR A  15
VAL A  18
ILE A  19
ILE A  39
PRO A  43
 None
 1.00A 2yzqA-2p9mA:
13.6		 2yzqA-2p9mA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YZQ_A_SAMA6075_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN PH1780)		 2p9m HYPOTHETICAL PROTEIN
MJ0922
(Methanocaldococc
us
jannaschii) 		5 / 12 THR A  80
VAL A  83
ILE A  84
ILE A 109
PRO A 113
 None
 0.54A 2yzqA-2p9mA:
13.6		 2yzqA-2p9mA:
23.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPB_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2p9m HYPOTHETICAL PROTEIN
MJ0922
(Methanocaldococc
us
jannaschii) 		5 / 12 ILE A  54
THR A  56
VAL A  83
ILE A  84
PRO A 113
 None
 0.68A 3kpbA-2p9mA:
17.2		 3kpbA-2p9mA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPB_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2p9m HYPOTHETICAL PROTEIN
MJ0922
(Methanocaldococc
us
jannaschii) 		5 / 12 ILE A  54
THR A  56
VAL A  83
ILE A 109
PRO A 113
 None
 0.55A 3kpbA-2p9mA:
17.2		 3kpbA-2p9mA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPB_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2p9m HYPOTHETICAL PROTEIN
MJ0922
(Methanocaldococc
us
jannaschii) 		5 / 12 ILE A 124
ASP A 129
THR A  15
VAL A  18
PRO A  43
 None
 0.52A 3kpbA-2p9mA:
17.2		 3kpbA-2p9mA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPB_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2p9m HYPOTHETICAL PROTEIN
MJ0922
(Methanocaldococc
us
jannaschii) 		6 / 12 ILE A 124
THR A  15
VAL A  18
ILE A  19
ILE A  39
PRO A  43
 None
 0.73A 3kpbA-2p9mA:
17.2		 3kpbA-2p9mA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPB_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2p9m HYPOTHETICAL PROTEIN
MJ0922
(Methanocaldococc
us
jannaschii) 		5 / 12 THR A  56
THR A  80
VAL A  83
ILE A  84
PRO A 113
 None
 0.79A 3kpbA-2p9mA:
17.2		 3kpbA-2p9mA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPB_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2p9m HYPOTHETICAL PROTEIN
MJ0922
(Methanocaldococc
us
jannaschii) 		5 / 12 THR A  56
THR A  80
VAL A  83
ILE A 109
PRO A 113
 None
 0.70A 3kpbA-2p9mA:
17.2		 3kpbA-2p9mA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPB_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2p9m HYPOTHETICAL PROTEIN
MJ0922
(Methanocaldococc
us
jannaschii) 		5 / 12 ILE A  54
THR A  56
VAL A  83
ILE A  84
PRO A 113
 None
 0.70A 3kpbC-2p9mA:
17.6		 3kpbC-2p9mA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPB_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2p9m HYPOTHETICAL PROTEIN
MJ0922
(Methanocaldococc
us
jannaschii) 		5 / 12 ILE A  54
THR A  56
VAL A  83
ILE A 109
PRO A 113
 None
 0.57A 3kpbC-2p9mA:
17.6		 3kpbC-2p9mA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPB_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2p9m HYPOTHETICAL PROTEIN
MJ0922
(Methanocaldococc
us
jannaschii) 		5 / 12 ILE A 124
ASP A 129
THR A  15
ILE A  39
PRO A  43
 None
 0.98A 3kpbC-2p9mA:
17.6		 3kpbC-2p9mA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPB_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2p9m HYPOTHETICAL PROTEIN
MJ0922
(Methanocaldococc
us
jannaschii) 		5 / 12 ILE A 124
ASP A 129
THR A  15
VAL A  18
PRO A  43
 None
 0.49A 3kpbC-2p9mA:
17.6		 3kpbC-2p9mA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPB_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2p9m HYPOTHETICAL PROTEIN
MJ0922
(Methanocaldococc
us
jannaschii) 		6 / 12 ILE A 124
THR A  15
VAL A  18
ILE A  19
ILE A  39
PRO A  43
 None
 0.66A 3kpbC-2p9mA:
17.6		 3kpbC-2p9mA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPB_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2p9m HYPOTHETICAL PROTEIN
MJ0922
(Methanocaldococc
us
jannaschii) 		5 / 12 THR A  56
THR A  80
VAL A  83
ILE A  84
PRO A 113
 None
 0.84A 3kpbC-2p9mA:
17.6		 3kpbC-2p9mA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPB_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2p9m HYPOTHETICAL PROTEIN
MJ0922
(Methanocaldococc
us
jannaschii) 		5 / 12 THR A  56
THR A  80
VAL A  83
ILE A 109
PRO A 113
 None
 0.75A 3kpbC-2p9mA:
17.6		 3kpbC-2p9mA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPB_D_SAMD1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2p9m HYPOTHETICAL PROTEIN
MJ0922
(Methanocaldococc
us
jannaschii) 		5 / 10 ILE A 124
THR A  15
VAL A  18
ILE A  19
ILE A  39
 None
 0.68A 3kpbD-2p9mA:
17.5		 3kpbD-2p9mA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPC_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2p9m HYPOTHETICAL PROTEIN
MJ0922
(Methanocaldococc
us
jannaschii) 		6 / 11 ILE A  54
THR A  56
VAL A  83
ILE A  84
ILE A 109
PRO A 113
 None
 0.66A 3kpcA-2p9mA:
18.4		 3kpcA-2p9mA:
37.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPC_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2p9m HYPOTHETICAL PROTEIN
MJ0922
(Methanocaldococc
us
jannaschii) 		5 / 11 ILE A 124
ASP A 129
THR A  15
ILE A  39
PRO A  43
 None
 1.05A 3kpcA-2p9mA:
18.4		 3kpcA-2p9mA:
37.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPC_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2p9m HYPOTHETICAL PROTEIN
MJ0922
(Methanocaldococc
us
jannaschii) 		7 / 11 ILE A 124
ASP A 129
THR A  15
VAL A  18
ILE A  19
SER A  40
PRO A  43
 None
 0.84A 3kpcA-2p9mA:
18.4		 3kpcA-2p9mA:
37.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPC_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2p9m HYPOTHETICAL PROTEIN
MJ0922
(Methanocaldococc
us
jannaschii) 		6 / 11 ILE A 124
VAL A  18
ILE A  19
ILE A  39
SER A  40
PRO A  43
 None
 1.00A 3kpcA-2p9mA:
18.4		 3kpcA-2p9mA:
37.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPC_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2p9m HYPOTHETICAL PROTEIN
MJ0922
(Methanocaldococc
us
jannaschii) 		5 / 11 THR A  56
ASP A  59
ILE A  84
ILE A 109
PRO A 113
 None
 1.05A 3kpcA-2p9mA:
18.4		 3kpcA-2p9mA:
37.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPC_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2p9m HYPOTHETICAL PROTEIN
MJ0922
(Methanocaldococc
us
jannaschii) 		6 / 11 THR A  56
THR A  80
VAL A  83
ILE A  84
ILE A 109
PRO A 113
 None
 0.79A 3kpcA-2p9mA:
18.4		 3kpcA-2p9mA:
37.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPD_B_SAMB1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2p9m HYPOTHETICAL PROTEIN
MJ0922
(Methanocaldococc
us
jannaschii) 		6 / 12 ILE A  54
THR A  56
VAL A  83
ILE A  84
ILE A 109
PRO A 113
 None
 0.68A 3kpdB-2p9mA:
17.5		 3kpdB-2p9mA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPD_B_SAMB1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2p9m HYPOTHETICAL PROTEIN
MJ0922
(Methanocaldococc
us
jannaschii) 		5 / 12 ILE A 124
ASP A 129
THR A  15
ILE A  39
PRO A  43
 None
 1.03A 3kpdB-2p9mA:
17.5		 3kpdB-2p9mA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPD_B_SAMB1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2p9m HYPOTHETICAL PROTEIN
MJ0922
(Methanocaldococc
us
jannaschii) 		7 / 12 ILE A 124
ASP A 129
THR A  15
VAL A  18
ILE A  19
SER A  40
PRO A  43
 None
 0.77A 3kpdB-2p9mA:
17.5		 3kpdB-2p9mA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPD_B_SAMB1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2p9m HYPOTHETICAL PROTEIN
MJ0922
(Methanocaldococc
us
jannaschii) 		7 / 12 ILE A 124
THR A  15
VAL A  18
ILE A  19
ILE A  39
SER A  40
PRO A  43
 None
 0.83A 3kpdB-2p9mA:
17.5		 3kpdB-2p9mA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPD_B_SAMB1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2p9m HYPOTHETICAL PROTEIN
MJ0922
(Methanocaldococc
us
jannaschii) 		5 / 12 THR A  56
ASP A  59
ILE A  84
ILE A 109
PRO A 113
 None
 1.05A 3kpdB-2p9mA:
17.5		 3kpdB-2p9mA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPD_B_SAMB1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2p9m HYPOTHETICAL PROTEIN
MJ0922
(Methanocaldococc
us
jannaschii) 		6 / 12 THR A  56
THR A  80
VAL A  83
ILE A  84
ILE A 109
PRO A 113
 None
 0.76A 3kpdB-2p9mA:
17.5		 3kpdB-2p9mA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPD_C_SAMC1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 2p9m HYPOTHETICAL PROTEIN
MJ0922
(Methanocaldococc
us
jannaschii) 		6 / 12 ILE A  54
THR A  56
VAL A  83
ILE A  84
ILE A 109
PRO A 113
 None
 0.70A 3kpdC-2p9mA:
17.9		 3kpdC-2p9mA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPD_C_SAMC1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 2p9m HYPOTHETICAL PROTEIN
MJ0922
(Methanocaldococc
us
jannaschii) 		6 / 12 ILE A 124
ASP A 129
THR A  15
VAL A  18
ILE A  19
PRO A  43
 None
 0.77A 3kpdC-2p9mA:
17.9		 3kpdC-2p9mA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPD_C_SAMC1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 2p9m HYPOTHETICAL PROTEIN
MJ0922
(Methanocaldococc
us
jannaschii) 		5 / 12 ILE A 124
VAL A  18
ILE A  19
ILE A  39
PRO A  43
 None
 0.70A 3kpdC-2p9mA:
17.9		 3kpdC-2p9mA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPD_C_SAMC1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 2p9m HYPOTHETICAL PROTEIN
MJ0922
(Methanocaldococc
us
jannaschii) 		6 / 12 THR A  56
ASP A  59
THR A  80
ILE A  84
ILE A 109
PRO A 113
 None
 1.25A 3kpdC-2p9mA:
17.9		 3kpdC-2p9mA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPD_C_SAMC1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 2p9m HYPOTHETICAL PROTEIN
MJ0922
(Methanocaldococc
us
jannaschii) 		6 / 12 THR A  56
THR A  80
VAL A  83
ILE A  84
ILE A 109
PRO A 113
 None
 0.81A 3kpdC-2p9mA:
17.9		 3kpdC-2p9mA:
37.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCU_A_SAMA603_0
(CYSTATHIONINE
BETA-SYNTHASE)		 2p9m HYPOTHETICAL PROTEIN
MJ0922
(Methanocaldococc
us
jannaschii) 		4 / 7 ASP A 127
GLN A 111
PRO A 113
ASP A  59
 None
 1.08A 4pcuA-2p9mA:
15.0		 4pcuA-2p9mA:
13.66