SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2p9w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_2
(PROTEIN (ADENOSINE
KINASE))		 2p9w MAL S 1 ALLERGENIC
PROTEIN
(Malassezia
sympodialis) 		3 / 3 LEU A 230
SER A 290
ASN A 287
 None
 0.67A 1bx4A-2p9wA:
undetectable		 1bx4A-2p9wA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKE_A_HSMA190_1
(NITROPHORIN 4)		 2p9w MAL S 1 ALLERGENIC
PROTEIN
(Malassezia
sympodialis) 		3 / 3 ASP A  39
LEU A  92
LEU A  90
 None
 0.75A 1ikeA-2p9wA:
undetectable		 1ikeA-2p9wA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 2p9w MAL S 1 ALLERGENIC
PROTEIN
(Malassezia
sympodialis) 		5 / 12 ALA A 182
GLY A 225
VAL A 162
PRO A 158
PHE A 150
 None
 1.16A 2okcB-2p9wA:
undetectable		 2okcB-2p9wA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDB_A_NPSA1591_1
(SERUM ALBUMIN)		 2p9w MAL S 1 ALLERGENIC
PROTEIN
(Malassezia
sympodialis) 		4 / 8 PHE A 282
LEU A 230
PHE A 224
GLY A 273
 None
 0.80A 2vdbA-2p9wA:
undetectable		 2vdbA-2p9wA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2p9w MAL S 1 ALLERGENIC
PROTEIN
(Malassezia
sympodialis) 		4 / 7 LEU A 131
SER A  78
GLY A  89
MET A  87
 None
 1.12A 3hcnA-2p9wA:
undetectable		 3hcnA-2p9wA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_2
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT
LIGHT CHAIN OF
ANTIBODY FAB
FRAGMENT)		 2p9w MAL S 1 ALLERGENIC
PROTEIN
(Malassezia
sympodialis) 		4 / 5 TYR A 313
GLN A 318
ILE A 347
LEU A 320
 None
 1.12A 3ls4L-2p9wA:
undetectable		 3ls4L-2p9wA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)		 2p9w MAL S 1 ALLERGENIC
PROTEIN
(Malassezia
sympodialis) 		5 / 12 LEU A 343
VAL A 272
TYR A 278
GLY A 273
LEU A 301
 None
 1.26A 3mecA-2p9wA:
undetectable		 3mecA-2p9wA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MED_A_65BA561_0
(P51 REVERSE
TRANSCRIPTASE
P66 REVERSE
TRANSCRIPTASE)		 2p9w MAL S 1 ALLERGENIC
PROTEIN
(Malassezia
sympodialis) 		5 / 12 LEU A 343
VAL A 272
TYR A 278
GLY A 273
LEU A 301
 None
 1.27A 3medA-2p9wA:
undetectable
3medB-2p9wA:
undetectable		 3medA-2p9wA:
18.36
3medB-2p9wA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 2p9w MAL S 1 ALLERGENIC
PROTEIN
(Malassezia
sympodialis) 		4 / 7 PHE A 176
SER A 194
VAL A 186
VAL A 146
 None
 1.13A 3n61A-2p9wA:
undetectable
3n61B-2p9wA:
undetectable		 3n61A-2p9wA:
21.22
3n61B-2p9wA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2p9w MAL S 1 ALLERGENIC
PROTEIN
(Malassezia
sympodialis) 		4 / 8 PHE A 176
SER A 194
VAL A 186
VAL A 146
 None
 1.14A 3nlrA-2p9wA:
undetectable
3nlrB-2p9wA:
undetectable		 3nlrA-2p9wA:
21.22
3nlrB-2p9wA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2p9w MAL S 1 ALLERGENIC
PROTEIN
(Malassezia
sympodialis) 		5 / 12 ILE A 347
VAL A 263
ALA A 291
ILE A 260
VAL A 245
 None
 1.02A 3w67C-2p9wA:
undetectable		 3w67C-2p9wA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_B_BEZB1000_0
(BENZOATE-COENZYME A
LIGASE)		 2p9w MAL S 1 ALLERGENIC
PROTEIN
(Malassezia
sympodialis) 		6 / 9 ALA A 177
TYR A 209
GLY A 225
ILE A 260
GLY A 211
ILE A 212
 None
 1.17A 4eatB-2p9wA:
undetectable		 4eatB-2p9wA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2p9w MAL S 1 ALLERGENIC
PROTEIN
(Malassezia
sympodialis) 		4 / 8 LEU A 131
SER A  78
GLY A  89
MET A  87
 None
 0.81A 4klrB-2p9wA:
undetectable		 4klrB-2p9wA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_A_SALA301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 2p9w MAL S 1 ALLERGENIC
PROTEIN
(Malassezia
sympodialis) 		4 / 5 ALA A 274
VAL A 272
PHE A 306
ILE A 347
 None
 0.99A 5of1A-2p9wA:
undetectable		 5of1A-2p9wA:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_B_SALB301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 2p9w MAL S 1 ALLERGENIC
PROTEIN
(Malassezia
sympodialis) 		4 / 5 ALA A 274
VAL A 272
PHE A 306
ILE A 347
 None
 0.99A 5of1B-2p9wA:
undetectable		 5of1B-2p9wA:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEC_C_RBTC601_1
(SCAFFOLD PROTEIN D13)		 2p9w MAL S 1 ALLERGENIC
PROTEIN
(Malassezia
sympodialis) 		5 / 12 VAL A 141
PRO A 242
VAL A 235
PHE A 124
PHE A 143
 None
GOL  A 601 (-4.4A)
None
None
None
 1.46A 6becA-2p9wA:
undetectable
6becB-2p9wA:
undetectable
6becC-2p9wA:
undetectable		 6becA-2p9wA:
21.29
6becB-2p9wA:
21.29
6becC-2p9wA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECE_C_DVAC3010_0
(VLM2
DODECADEPSIPEPTIDE)		 2p9w MAL S 1 ALLERGENIC
PROTEIN
(Malassezia
sympodialis) 		3 / 3 ALA A 177
PHE A 159
GLN A 116
 None
 0.74A 6eceA-2p9wA:
undetectable		 6eceA-2p9wA:
18.64