SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2p9x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_2
(SECRETED ASPARTIC
PROTEASE)		 2p9x HYPOTHETICAL PROTEIN
PH0832
(Pyrococcus
horikoshii) 		4 / 6 SER A   2
TYR A  43
VAL A  90
THR A  11
 ZN  A2001 ( 4.9A)
None
None
None
 1.14A 3tneA-2p9xA:
undetectable		 3tneA-2p9xA:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2p9x HYPOTHETICAL PROTEIN
PH0832
(Pyrococcus
horikoshii) 		4 / 8 ALA A  83
GLU A  92
ILE A  93
ILE A   7
 None
 0.94A 4ndnB-2p9xA:
undetectable		 4ndnB-2p9xA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_B_FK5B201_1
(FK506-BINDING
PROTEIN 1)		 2p9x HYPOTHETICAL PROTEIN
PH0832
(Pyrococcus
horikoshii) 		5 / 11 PHE A  57
VAL A  26
ILE A  39
ILE A  12
ILE A  13
 None
 1.27A 5hw8B-2p9xA:
undetectable		 5hw8B-2p9xA:
19.20