SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2pag'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NT5_A_DVAA6_0 (GRAMICIDIN A)	2pag	HYPOTHETICAL PROTEIN (Pseudomonas syringae group genomosp. 3)	3 / 3	ALA A 11 VAL A 53 TRP A 132	None	0.90A	1nt5A-2pagA: undetectable	1nt5A-2pagA: 9.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NT5_B_DVAB6_0 (GRAMICIDIN A)	2pag	HYPOTHETICAL PROTEIN (Pseudomonas syringae group genomosp. 3)	3 / 3	ALA A 11 VAL A 53 TRP A 132	None	0.90A	1nt5B-2pagA: undetectable	1nt5B-2pagA: 9.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3B0W_B_DGXB1_2 (NUCLEAR RECEPTOR ROR-GAMMA)	2pag	HYPOTHETICAL PROTEIN (Pseudomonas syringae group genomosp. 3)	3 / 3	LEU A 34 VAL A 83 ARG A 85	None	0.75A	3b0wB-2pagA: undetectable	3b0wB-2pagA: 19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JX1_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2pag	HYPOTHETICAL PROTEIN (Pseudomonas syringae group genomosp. 3)	4 / 8	PHE A 42 SER A 123 VAL A 106 TRP A 127	None	1.30A	3jx1A-2pagA: undetectable 3jx1B-2pagA: undetectable	3jx1A-2pagA: 16.01 3jx1B-2pagA: 16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N61_B_H4BB760_1 (NITRIC OXIDE SYNTHASE)	2pag	HYPOTHETICAL PROTEIN (Pseudomonas syringae group genomosp. 3)	4 / 7	PHE A 42 SER A 123 VAL A 106 TRP A 127	None	1.28A	3n61A-2pagA: undetectable 3n61B-2pagA: undetectable	3n61A-2pagA: 16.01 3n61B-2pagA: 16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NLY_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2pag	HYPOTHETICAL PROTEIN (Pseudomonas syringae group genomosp. 3)	4 / 8	PHE A 42 SER A 123 VAL A 106 TRP A 127	None	1.31A	3nlyA-2pagA: undetectable 3nlyB-2pagA: undetectable	3nlyA-2pagA: 16.01 3nlyB-2pagA: 16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RQL_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2pag	HYPOTHETICAL PROTEIN (Pseudomonas syringae group genomosp. 3)	4 / 8	PHE A 42 SER A 123 VAL A 106 TRP A 127	None	1.31A	3rqlA-2pagA: undetectable 3rqlB-2pagA: undetectable	3rqlA-2pagA: 16.01 3rqlB-2pagA: 16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CAP_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2pag	HYPOTHETICAL PROTEIN (Pseudomonas syringae group genomosp. 3)	4 / 8	PHE A 42 SER A 123 VAL A 106 TRP A 127	None	1.31A	4capA-2pagA: undetectable 4capB-2pagA: undetectable	4capA-2pagA: 16.01 4capB-2pagA: 16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D32_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2pag	HYPOTHETICAL PROTEIN (Pseudomonas syringae group genomosp. 3)	4 / 8	PHE A 42 SER A 123 VAL A 106 TRP A 127	None	1.24A	4d32A-2pagA: undetectable 4d32B-2pagA: undetectable	4d32A-2pagA: 16.01 4d32B-2pagA: 16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V3Y_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2pag	HYPOTHETICAL PROTEIN (Pseudomonas syringae group genomosp. 3)	4 / 8	PHE A 42 SER A 123 VAL A 106 TRP A 127	None	1.31A	4v3yA-2pagA: undetectable 4v3yB-2pagA: undetectable	4v3yA-2pagA: 16.01 4v3yB-2pagA: 16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZBQ_A_DIFA602_1 (SERUM ALBUMIN)	2pag	HYPOTHETICAL PROTEIN (Pseudomonas syringae group genomosp. 3)	4 / 8	LEU A 133 ASN A 12 ALA A 11 GLU A 6	None	0.68A	4zbqA-2pagA: undetectable	4zbqA-2pagA: 13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UO7_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2pag	HYPOTHETICAL PROTEIN (Pseudomonas syringae group genomosp. 3)	4 / 8	SER A 123 VAL A 106 TRP A 127 PHE A 42	None	1.31A	5uo7A-2pagA: undetectable 5uo7B-2pagA: undetectable	5uo7A-2pagA: 15.91 5uo7B-2pagA: 15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BRD_A_RFPA502_1 (RIFAMPIN MONOOXYGENASE)	2pag	HYPOTHETICAL PROTEIN (Pseudomonas syringae group genomosp. 3)	5 / 12	VAL A 60 PHE A 42 VAL A 116 THR A 105 GLY A 104	None None None CA A 201 (-3.1A) None	1.40A	6brdA-2pagA: undetectable	6brdA-2pagA: 20.74

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1NT5_A_DVAA6_0","GRAMICIDIN A","2pag","HYPOTHETICAL PROTEIN","Pseudomonas syringae group genomosp. 3",3,"ALA A  11;VAL A  53;TRP A 132","None","0.90A","1nt5A-2pagA:undetectable","1nt5A-2pagA:9.90"],["1NT5_B_DVAB6_0","GRAMICIDIN A","2pag","HYPOTHETICAL PROTEIN","Pseudomonas syringae group genomosp. 3",3,"ALA A  11;VAL A  53;TRP A 132","None","0.90A","1nt5B-2pagA:undetectable","1nt5B-2pagA:9.90"],["3B0W_B_DGXB1_2","NUCLEAR RECEPTOR ROR-GAMMA","2pag","HYPOTHETICAL PROTEIN","Pseudomonas syringae group genomosp. 3",3,"LEU A  34;VAL A  83;ARG A  85","None","0.75A","3b0wB-2pagA:undetectable","3b0wB-2pagA:19.84"],["3JX1_B_H4BB760_1","NITRIC OXIDE SYNTHASE, BRAIN;NITRIC OXIDE SYNTHASE, BRAIN","2pag","HYPOTHETICAL PROTEIN","Pseudomonas syringae group genomosp. 3",4,"PHE A  42;SER A 123;VAL A 106;TRP A 127","None","1.30A","3jx1A-2pagA:undetectable;3jx1B-2pagA:undetectable","3jx1A-2pagA:16.01;3jx1B-2pagA:16.01"],["3N61_B_H4BB760_1","NITRIC OXIDE SYNTHASE;NITRIC OXIDE SYNTHASE","2pag","HYPOTHETICAL PROTEIN","Pseudomonas syringae group genomosp. 3",4,"PHE A  42;SER A 123;VAL A 106;TRP A 127","None","1.28A","3n61A-2pagA:undetectable;3n61B-2pagA:undetectable","3n61A-2pagA:16.01;3n61B-2pagA:16.01"],["3NLY_B_H4BB760_1","NITRIC OXIDE SYNTHASE, BRAIN;NITRIC OXIDE SYNTHASE, BRAIN","2pag","HYPOTHETICAL PROTEIN","Pseudomonas syringae group genomosp. 3",4,"PHE A  42;SER A 123;VAL A 106;TRP A 127","None","1.31A","3nlyA-2pagA:undetectable;3nlyB-2pagA:undetectable","3nlyA-2pagA:16.01;3nlyB-2pagA:16.01"],["3RQL_B_H4BB760_1","NITRIC OXIDE SYNTHASE, BRAIN;NITRIC OXIDE SYNTHASE, BRAIN","2pag","HYPOTHETICAL PROTEIN","Pseudomonas syringae group genomosp. 3",4,"PHE A  42;SER A 123;VAL A 106;TRP A 127","None","1.31A","3rqlA-2pagA:undetectable;3rqlB-2pagA:undetectable","3rqlA-2pagA:16.01;3rqlB-2pagA:16.01"],["4CAP_B_H4BB760_1","NITRIC OXIDE SYNTHASE, BRAIN;NITRIC OXIDE SYNTHASE, BRAIN","2pag","HYPOTHETICAL PROTEIN","Pseudomonas syringae group genomosp. 3",4,"PHE A  42;SER A 123;VAL A 106;TRP A 127","None","1.31A","4capA-2pagA:undetectable;4capB-2pagA:undetectable","4capA-2pagA:16.01;4capB-2pagA:16.01"],["4D32_B_H4BB760_1","NITRIC OXIDE SYNTHASE, BRAIN;NITRIC OXIDE SYNTHASE, BRAIN","2pag","HYPOTHETICAL PROTEIN","Pseudomonas syringae group genomosp. 3",4,"PHE A  42;SER A 123;VAL A 106;TRP A 127","None","1.24A","4d32A-2pagA:undetectable;4d32B-2pagA:undetectable","4d32A-2pagA:16.01;4d32B-2pagA:16.01"],["4V3Y_B_H4BB760_1","NITRIC OXIDE SYNTHASE, BRAIN;NITRIC OXIDE SYNTHASE, BRAIN","2pag","HYPOTHETICAL PROTEIN","Pseudomonas syringae group genomosp. 3",4,"PHE A  42;SER A 123;VAL A 106;TRP A 127","None","1.31A","4v3yA-2pagA:undetectable;4v3yB-2pagA:undetectable","4v3yA-2pagA:16.01;4v3yB-2pagA:16.01"],["4ZBQ_A_DIFA602_1","SERUM ALBUMIN","2pag","HYPOTHETICAL PROTEIN","Pseudomonas syringae group genomosp. 3",4,"LEU A 133;ASN A  12;ALA A  11;GLU A   6","None","0.68A","4zbqA-2pagA:undetectable","4zbqA-2pagA:13.83"],["5UO7_A_H4BA802_1","NITRIC OXIDE SYNTHASE, BRAIN;NITRIC OXIDE SYNTHASE, BRAIN","2pag","HYPOTHETICAL PROTEIN","Pseudomonas syringae group genomosp. 3",4,"SER A 123;VAL A 106;TRP A 127;PHE A  42","None","1.31A","5uo7A-2pagA:undetectable;5uo7B-2pagA:undetectable","5uo7A-2pagA:15.91;5uo7B-2pagA:15.91"],["6BRD_A_RFPA502_1","RIFAMPIN MONOOXYGENASE","2pag","HYPOTHETICAL PROTEIN","Pseudomonas syringae group genomosp. 3",5,"VAL A  60;PHE A  42;VAL A 116;THR A 105;GLY A 104","None;None;None; CA A 201 (-3.1A);None","1.40A","6brdA-2pagA:undetectable","6brdA-2pagA:20.74"]]