SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2pal'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EA1_A_TPFA470_1
(CYTOCHROME P450
51-LIKE RV0764C)		 2pal PARVALBUMIN
(Esox
lucius) 		4 / 8 PHE A  30
PHE A  24
THR A  82
LEU A  63
 None
 1.25A 1ea1A-2palA:
undetectable		 1ea1A-2palA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1475_0
(MJ0495-LIKE PROTEIN)		 2pal PARVALBUMIN
(Esox
lucius) 		4 / 8 ILE A  50
ASP A  51
ILE A  58
GLY A  89
 None
MN  A 111 ( 2.9A)
None
None
 0.77A 4ac9C-2palA:
undetectable		 4ac9C-2palA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2pal PARVALBUMIN
(Esox
lucius) 		4 / 8 ILE A  50
ASP A  51
ILE A  58
GLY A  89
 None
MN  A 111 ( 2.9A)
None
None
 0.76A 4acaC-2palA:
undetectable		 4acaC-2palA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2pal PARVALBUMIN
(Esox
lucius) 		4 / 8 ILE A  50
ASP A  51
ILE A  58
GLY A  89
 None
MN  A 111 ( 2.9A)
None
None
 0.78A 4acbC-2palA:
undetectable		 4acbC-2palA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_A_NCTA501_1
(CYTOCHROME P450 2A6)		 2pal PARVALBUMIN
(Esox
lucius) 		4 / 7 PHE A  29
PHE A  70
ILE A  50
PHE A  66
 None
 0.87A 4ejjA-2palA:
undetectable		 4ejjA-2palA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M51_A_BEZA501_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 2pal PARVALBUMIN
(Esox
lucius) 		4 / 6 ILE A  50
ILE A 106
PHE A  70
LEU A   6
 None
None
None
ACE  A   0 ( 3.5A)
 0.92A 4m51A-2palA:
undetectable		 4m51A-2palA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP9_C_1WEC706_1
(TRANSPORTER)		 2pal PARVALBUMIN
(Esox
lucius) 		4 / 4 PHE A  57
ASP A  51
GLY A  98
SER A  55
 None
MN  A 111 ( 2.9A)
None
MN  A 111 ( 2.3A)
 1.45A 4xp9C-2palA:
undetectable		 4xp9C-2palA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA602_1
(SERUM ALBUMIN)		 2pal PARVALBUMIN
(Esox
lucius) 		4 / 8 LEU A  35
ASP A  42
ALA A  46
VAL A  49
 None
 0.64A 4zbqA-2palA:
undetectable		 4zbqA-2palA:
11.66