SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2pau'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RLB_F_REAF177_1 (RETINOL BINDING PROTEIN)	2pau	5'-DEOXYNUCLEOTIDASE YFBR (Escherichia coli)	5 / 11	LEU A 13 ALA A 38 VAL A 73 LEU A 74 TYR A 67	None	1.11A	1rlbF-2pauA: undetectable	1rlbF-2pauA: 18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_H_TC9H1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	2pau	5'-DEOXYNUCLEOTIDASE YFBR (Escherichia coli)	4 / 7	GLN A 101 ILE A 120 ASP A 69 SER A 34	None None CO A 201 ( 2.6A) None	1.20A	2xytI-2pauA: undetectable	2xytI-2pauA: 24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LN1_D_CELD682_2 (PROSTAGLANDIN G/H SYNTHASE 2)	2pau	5'-DEOXYNUCLEOTIDASE YFBR (Escherichia coli)	4 / 5	LEU A 10 ARG A 113 ILE A 115 PHE A 116	None	1.16A	3ln1D-2pauA: undetectable	3ln1D-2pauA: 16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UY4_A_PAUA302_0 (PANTOTHENATE SYNTHETASE)	2pau	5'-DEOXYNUCLEOTIDASE YFBR (Escherichia coli)	4 / 8	ARG A 18 HIS A 33 VAL A 37 VAL A 40	D5M A 301 (-3.3A) CO A 201 ( 3.2A) None None	0.71A	3uy4A-2pauA: undetectable	3uy4A-2pauA: 22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NU7_A_RTLA201_0 (RETINOL-BINDING PROTEIN 4)	2pau	5'-DEOXYNUCLEOTIDASE YFBR (Escherichia coli)	4 / 8	LEU A 13 ALA A 38 VAL A 73 TYR A 67	None	0.96A	5nu7A-2pauA: undetectable	5nu7A-2pauA: 20.85

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1RLB_F_REAF177_1","RETINOL BINDING PROTEIN","2pau","5'-DEOXYNUCLEOTIDASE YFBR","Escherichia coli",5,"LEU A  13;ALA A  38;VAL A  73;LEU A  74;TYR A  67","None","1.11A","1rlbF-2pauA:undetectable","1rlbF-2pauA:18.10"],["2XYT_H_TC9H1206_2","SOLUBLE ACETYLCHOLINE RECEPTOR;SOLUBLE ACETYLCHOLINE RECEPTOR","2pau","5'-DEOXYNUCLEOTIDASE YFBR","Escherichia coli",4,"GLN A 101;ILE A 120;ASP A  69;SER A  34","None;None; CO A 201 ( 2.6A);None","1.20A","2xytI-2pauA:undetectable","2xytI-2pauA:24.14"],["3LN1_D_CELD682_2","PROSTAGLANDIN G\/H SYNTHASE 2","2pau","5'-DEOXYNUCLEOTIDASE YFBR","Escherichia coli",4,"LEU A  10;ARG A 113;ILE A 115;PHE A 116","None","1.16A","3ln1D-2pauA:undetectable","3ln1D-2pauA:16.35"],["3UY4_A_PAUA302_0","PANTOTHENATE SYNTHETASE","2pau","5'-DEOXYNUCLEOTIDASE YFBR","Escherichia coli",4,"ARG A  18;HIS A  33;VAL A  37;VAL A  40","D5M A 301 (-3.3A); CO A 201 ( 3.2A);None;None","0.71A","3uy4A-2pauA:undetectable","3uy4A-2pauA:22.07"],["5NU7_A_RTLA201_0","RETINOL-BINDING PROTEIN 4","2pau","5'-DEOXYNUCLEOTIDASE YFBR","Escherichia coli",4,"LEU A  13;ALA A  38;VAL A  73;TYR A  67","None","0.96A","5nu7A-2pauA:undetectable","5nu7A-2pauA:20.85"]]