SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2pbc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		8 / 9 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
 0.80A 1bkfA-2pbcA:
15.5		 1bkfA-2pbcA:
47.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1C9H_A_RAPA108_1
(FKBP12.6)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		7 / 12 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TYR A 112
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
None
None
 0.77A 1c9hA-2pbcA:
15.2		 1c9hA-2pbcA:
42.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1C9H_A_RAPA108_1
(FKBP12.6)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		7 / 12 TYR A  56
PHE A  76
VAL A  85
ILE A  86
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
None
None
None
 0.88A 1c9hA-2pbcA:
15.2		 1c9hA-2pbcA:
42.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FAP_A_RAPA108_1
(FK506-BINDING
PROTEIN)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		9 / 12 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.79A 1fapA-2pbcA:
16.1		 1fapA-2pbcA:
47.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FAP_A_RAPA108_1
(FK506-BINDING
PROTEIN)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		5 / 12 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A 121
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
None
 0.91A 1fapA-2pbcA:
16.1		 1fapA-2pbcA:
47.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKB_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		8 / 12 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
 0.77A 1fkbA-2pbcA:
15.8		 1fkbA-2pbcA:
47.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKB_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		5 / 12 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A 121
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
None
 0.93A 1fkbA-2pbcA:
15.8		 1fkbA-2pbcA:
47.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		6 / 11 PHE A  78
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 None
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 1.48A 1fkfA-2pbcA:
15.5		 1fkfA-2pbcA:
47.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		9 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.83A 1fkfA-2pbcA:
15.5		 1fkfA-2pbcA:
47.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKJ_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		6 / 11 PHE A  78
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 None
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 1.48A 1fkjA-2pbcA:
15.5		 1fkjA-2pbcA:
47.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKJ_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		9 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.85A 1fkjA-2pbcA:
15.5		 1fkjA-2pbcA:
47.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKL_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		9 / 12 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.88A 1fklA-2pbcA:
15.8		 1fklA-2pbcA:
46.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKL_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		5 / 12 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A 121
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
None
 0.97A 1fklA-2pbcA:
15.8		 1fklA-2pbcA:
46.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_D_DEXD4999_2
(GLUCOCORTICOID
RECEPTOR)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		4 / 5 LEU A  70
TRP A  89
MET A  54
GLN A  72
 None
PEG  A 201 (-3.7A)
None
None
 1.50A 1p93D-2pbcA:
undetectable		 1p93D-2pbcA:
17.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PBK_A_RAPA225_1
(FKBP25)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		9 / 12 TYR A  56
ASP A  67
GLY A  83
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
None
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.50A 1pbkA-2pbcA:
15.0		 1pbkA-2pbcA:
43.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PBK_A_RAPA225_1
(FKBP25)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		7 / 12 TYR A  56
ASP A  67
VAL A  85
TRP A  89
ALA A 117
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 (-3.6A)
PEG  A 201 (-3.7A)
None
None
None
 1.13A 1pbkA-2pbcA:
15.0		 1pbkA-2pbcA:
43.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q6I_A_FK5A301_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		8 / 9 TYR A  56
ASP A  67
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.69A 1q6iA-2pbcA:
13.3		 1q6iA-2pbcA:
25.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q6I_B_FK5B401_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		8 / 10 TYR A  56
ASP A  67
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.57A 1q6iB-2pbcA:
13.2		 1q6iB-2pbcA:
25.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TCO_C_FK5C509_2
(FK506-BINDING
PROTEIN)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		9 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.77A 1tcoC-2pbcA:
15.9		 1tcoC-2pbcA:
47.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAT_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		9 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.71A 1yatA-2pbcA:
16.4		 1yatA-2pbcA:
45.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG3_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		8 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
 0.76A 2dg3A-2pbcA:
15.5		 2dg3A-2pbcA:
47.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG4_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		7 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TYR A 112
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
None
None
 0.81A 2dg4A-2pbcA:
15.1		 2dg4A-2pbcA:
46.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG4_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		5 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A 121
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
None
 0.95A 2dg4A-2pbcA:
15.1		 2dg4A-2pbcA:
46.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG9_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		7 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TYR A 112
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
None
None
 0.74A 2dg9A-2pbcA:
15.4		 2dg9A-2pbcA:
46.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG9_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		5 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A 121
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
None
 0.96A 2dg9A-2pbcA:
15.4		 2dg9A-2pbcA:
46.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FKE_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		9 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.83A 2fkeA-2pbcA:
15.7		 2fkeA-2pbcA:
47.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VCD_A_RAPA138_1
(OUTER MEMBRANE
PROTEIN MIP)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		7 / 11 TYR A  56
PHE A  66
ASP A  67
VAL A  85
ILE A  86
TRP A  89
TYR A 112
 PEG  A 201 (-4.4A)
None
None
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
 0.86A 2vcdA-2pbcA:
10.6		 2vcdA-2pbcA:
35.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VN1_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		9 / 11 TYR A  56
PHE A  66
ASP A  67
PHE A  76
VAL A  85
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.7A)
None
None
None
 0.81A 2vn1A-2pbcA:
15.2		 2vn1A-2pbcA:
42.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VN1_B_FK5B501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		8 / 10 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
 0.69A 2vn1B-2pbcA:
15.2		 2vn1B-2pbcA:
42.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IHZ_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		6 / 10 PHE A  78
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 None
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 1.45A 3ihzA-2pbcA:
15.3		 3ihzA-2pbcA:
42.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IHZ_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		9 / 10 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.75A 3ihzA-2pbcA:
15.3		 3ihzA-2pbcA:
42.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IHZ_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		5 / 8 TYR A  56
ASP A  67
PHE A  76
TRP A  89
ILE A 121
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.7A)
None
 0.86A 3ihzB-2pbcA:
15.4		 3ihzB-2pbcA:
42.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IHZ_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		5 / 8 TYR A  56
ASP A  67
TRP A  89
TYR A 112
ILE A 121
 PEG  A 201 (-4.4A)
None
PEG  A 201 (-3.7A)
None
None
 0.70A 3ihzB-2pbcA:
15.4		 3ihzB-2pbcA:
42.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KZ7_A_RAPA225_1
(FK506-BINDING
PROTEIN 3)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		8 / 10 TYR A  56
ASP A  67
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.56A 3kz7A-2pbcA:
14.9		 3kz7A-2pbcA:
44.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O5R_A_FK5A1001_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		9 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.59A 3o5rA-2pbcA:
15.2		 3o5rA-2pbcA:
42.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UF8_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		9 / 10 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.75A 3uf8A-2pbcA:
16.3		 3uf8A-2pbcA:
33.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UQA_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		9 / 10 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.81A 3uqaA-2pbcA:
16.3		 3uqaA-2pbcA:
33.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UQB_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		6 / 8 TYR A  56
PHE A  76
VAL A  85
ILE A  86
TRP A  89
PHE A 129
 PEG  A 201 (-4.4A)
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
 0.59A 3uqbA-2pbcA:
15.9		 3uqbA-2pbcA:
32.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UQB_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		7 / 8 TYR A  56
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.54A 3uqbA-2pbcA:
15.9		 3uqbA-2pbcA:
32.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VAW_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN
SMT3,PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		6 / 11 PHE A  78
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 None
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 1.47A 3vawA-2pbcA:
15.8		 3vawA-2pbcA:
33.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VAW_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN
SMT3,PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		9 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.77A 3vawA-2pbcA:
15.8		 3vawA-2pbcA:
33.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRH_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		9 / 12 TYR A  56
ASP A  67
GLN A  84
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
None
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.77A 4drhA-2pbcA:
14.1		 4drhA-2pbcA:
38.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRH_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		9 / 12 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.84A 4drhA-2pbcA:
14.1		 4drhA-2pbcA:
38.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRH_D_RAPD201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		10 / 12 TYR A  56
ASP A  67
PHE A  76
GLN A  84
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
None
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.80A 4drhD-2pbcA:
13.9		 4drhD-2pbcA:
38.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRI_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		9 / 11 TYR A  56
ASP A  67
GLN A  84
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
None
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.76A 4driA-2pbcA:
15.5		 4driA-2pbcA:
38.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRI_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		9 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.75A 4driA-2pbcA:
15.5		 4driA-2pbcA:
38.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRJ_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		9 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.77A 4drjA-2pbcA:
15.4		 4drjA-2pbcA:
36.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ2_A_FK5A200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		6 / 11 PHE A  78
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 None
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 1.45A 4dz2A-2pbcA:
16.2
4dz2B-2pbcA:
16.1		 4dz2A-2pbcA:
56.25
4dz2B-2pbcA:
56.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ2_A_FK5A200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		9 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.77A 4dz2A-2pbcA:
16.2
4dz2B-2pbcA:
16.1		 4dz2A-2pbcA:
56.25
4dz2B-2pbcA:
56.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ2_B_FK5B200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		6 / 11 PHE A  78
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 None
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 1.43A 4dz2A-2pbcA:
16.2
4dz2B-2pbcA:
16.1		 4dz2A-2pbcA:
56.25
4dz2B-2pbcA:
56.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ2_B_FK5B200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		9 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.78A 4dz2A-2pbcA:
16.2
4dz2B-2pbcA:
16.1		 4dz2A-2pbcA:
56.25
4dz2B-2pbcA:
56.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ3_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		9 / 10 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.76A 4dz3A-2pbcA:
16.4		 4dz3A-2pbcA:
57.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ3_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		6 / 10 PHE A  78
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 None
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 1.39A 4dz3B-2pbcA:
16.3		 4dz3B-2pbcA:
57.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ3_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		9 / 10 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.78A 4dz3B-2pbcA:
16.3		 4dz3B-2pbcA:
57.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAX_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		9 / 10 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.77A 4laxA-2pbcA:
15.6		 4laxA-2pbcA:
29.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NNR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		9 / 12 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.70A 4nnrA-2pbcA:
18.7
4nnrB-2pbcA:
18.9		 4nnrA-2pbcA:
71.13
4nnrB-2pbcA:
71.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NNR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		9 / 10 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.70A 4nnrB-2pbcA:
18.9		 4nnrB-2pbcA:
71.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		5 / 10 TYR A  56
ASP A  67
ILE A  86
TYR A 112
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 (-3.8A)
None
None
 0.58A 4odoA-2pbcA:
12.7		 4odoA-2pbcA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		5 / 10 TYR A  56
ASP A  67
ILE A  86
TYR A 112
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 (-3.8A)
None
None
 0.52A 4odoB-2pbcA:
12.4		 4odoB-2pbcA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_C_FK5C204_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		5 / 10 TYR A  56
ASP A  67
ILE A  86
TYR A 112
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 (-3.8A)
None
None
 0.50A 4odoC-2pbcA:
12.3		 4odoC-2pbcA:
22.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ODR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		6 / 12 TYR A  56
ASP A  67
ILE A  86
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 (-3.8A)
None
None
None
 0.54A 4odrA-2pbcA:
14.5
4odrB-2pbcA:
14.3		 4odrA-2pbcA:
33.33
4odrB-2pbcA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ODR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		5 / 11 TYR A  56
ASP A  67
ILE A  86
TYR A 112
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 (-3.8A)
None
None
 0.58A 4odrA-2pbcA:
14.5
4odrB-2pbcA:
14.3		 4odrA-2pbcA:
33.33
4odrB-2pbcA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QT2_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		9 / 10 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.78A 4qt2A-2pbcA:
15.6		 4qt2A-2pbcA:
41.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QT3_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		9 / 10 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.83A 4qt3A-2pbcA:
13.9		 4qt3A-2pbcA:
41.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_C_PACC601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		5 / 12 SER A  69
PRO A  75
PHE A  78
TRP A  89
VAL A 131
 None
None
None
PEG  A 201 (-3.7A)
None
 1.44A 4yfbC-2pbcA:
undetectable		 4yfbC-2pbcA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_F_PACF601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		5 / 12 SER A  69
PRO A  75
PHE A  78
TRP A  89
VAL A 131
 None
None
None
PEG  A 201 (-3.7A)
None
 1.44A 4yfbF-2pbcA:
undetectable		 4yfbF-2pbcA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_I_PACI601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		5 / 12 SER A  69
PRO A  75
PHE A  78
TRP A  89
VAL A 131
 None
None
None
PEG  A 201 (-3.7A)
None
 1.41A 4yfbI-2pbcA:
undetectable		 4yfbI-2pbcA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_L_PACL601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		5 / 12 SER A  69
PRO A  75
PHE A  78
TRP A  89
VAL A 131
 None
None
None
PEG  A 201 (-3.7A)
None
 1.42A 4yfbL-2pbcA:
undetectable		 4yfbL-2pbcA:
9.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5B8I_C_FK5C201_3
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		9 / 12 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.85A 5b8iC-2pbcA:
15.5		 5b8iC-2pbcA:
39.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D75_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		8 / 11 TYR A  56
ASP A  67
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.62A 5d75A-2pbcA:
15.3		 5d75A-2pbcA:
42.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GPG_A_RAPA301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		8 / 11 TYR A  56
ASP A  67
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.59A 5gpgA-2pbcA:
15.7		 5gpgA-2pbcA:
45.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HKG_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1B)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		8 / 12 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
None
None
None
 0.91A 5hkgA-2pbcA:
15.2		 5hkgA-2pbcA:
42.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HUA_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		8 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
 0.66A 5huaA-2pbcA:
16.5		 5huaA-2pbcA:
48.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		8 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
 0.75A 5hw8A-2pbcA:
15.4
5hw8D-2pbcA:
15.2		 5hw8A-2pbcA:
44.14
5hw8D-2pbcA:
44.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_B_FK5B201_1
(FK506-BINDING
PROTEIN 1)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		5 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A 121
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
None
 1.03A 5hw8B-2pbcA:
15.3		 5hw8B-2pbcA:
44.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_B_FK5B201_1
(FK506-BINDING
PROTEIN 1)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		8 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.7A)
None
None
None
 0.73A 5hw8B-2pbcA:
15.3		 5hw8B-2pbcA:
44.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_C_FK5C201_1
(FK506-BINDING
PROTEIN 1)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		8 / 10 TYR A  56
ASP A  67
VAL A  85
ILE A  86
TRP A  89
TYR A 112
LEU A 127
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.47A 5hw8C-2pbcA:
15.0
5hw8H-2pbcA:
13.6		 5hw8C-2pbcA:
44.14
5hw8H-2pbcA:
44.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_D_FK5D201_1
(FK506-BINDING
PROTEIN 1)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		8 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
 0.64A 5hw8D-2pbcA:
15.2		 5hw8D-2pbcA:
44.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_D_FK5D201_1
(FK506-BINDING
PROTEIN 1)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		5 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A 121
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
None
 0.98A 5hw8D-2pbcA:
15.2		 5hw8D-2pbcA:
44.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_D_FK5D201_1
(FK506-BINDING
PROTEIN 1)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		8 / 11 TYR A  56
ASP A  67
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.61A 5hw8D-2pbcA:
15.2		 5hw8D-2pbcA:
44.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_E_FK5E201_1
(FK506-BINDING
PROTEIN 1)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		6 / 11 PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
 PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
 1.45A 5hw8E-2pbcA:
14.8		 5hw8E-2pbcA:
44.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_E_FK5E201_1
(FK506-BINDING
PROTEIN 1)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		8 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
 0.65A 5hw8E-2pbcA:
14.8		 5hw8E-2pbcA:
44.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_E_FK5E201_1
(FK506-BINDING
PROTEIN 1)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		5 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A 121
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
None
 1.02A 5hw8E-2pbcA:
14.8		 5hw8E-2pbcA:
44.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_F_FK5F201_1
(FK506-BINDING
PROTEIN 1)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		8 / 12 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
 0.62A 5hw8B-2pbcA:
15.3
5hw8F-2pbcA:
12.8
5hw8G-2pbcA:
14.5		 5hw8B-2pbcA:
44.14
5hw8F-2pbcA:
44.14
5hw8G-2pbcA:
44.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_F_FK5F201_1
(FK506-BINDING
PROTEIN 1)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		5 / 12 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A 121
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
None
 1.04A 5hw8B-2pbcA:
15.3
5hw8F-2pbcA:
12.8
5hw8G-2pbcA:
14.5		 5hw8B-2pbcA:
44.14
5hw8F-2pbcA:
44.14
5hw8G-2pbcA:
44.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_G_FK5G201_2
(FK506-BINDING
PROTEIN 1)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		9 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.72A 5hw8G-2pbcA:
14.5		 5hw8G-2pbcA:
44.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_H_FK5H201_1
(FK506-BINDING
PROTEIN 1)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		7 / 8 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
 0.68A 5hw8H-2pbcA:
13.6		 5hw8H-2pbcA:
44.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HWC_A_FK5A201_1
(FK506-BINDING
PROTEIN 1A)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		9 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.67A 5hwcA-2pbcA:
16.6		 5hwcA-2pbcA:
47.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_A_FK5A201_0
(PEPTIDYLPROLYL
ISOMERASE)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		9 / 12 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.81A 6mkeA-2pbcA:
15.1
6mkeD-2pbcA:
15.3		 6mkeA-2pbcA:
56.36
6mkeD-2pbcA:
56.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_B_FK5B201_0
(PEPTIDYLPROLYL
ISOMERASE)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		9 / 12 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.75A 6mkeB-2pbcA:
15.2
6mkeC-2pbcA:
15.2		 6mkeB-2pbcA:
56.36
6mkeC-2pbcA:
56.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_C_FK5C201_1
(PEPTIDYLPROLYL
ISOMERASE)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		9 / 10 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.67A 6mkeC-2pbcA:
15.2		 6mkeC-2pbcA:
56.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_D_FK5D201_1
(PEPTIDYLPROLYL
ISOMERASE)		 2pbc FK506-BINDING
PROTEIN 2
(Homo
sapiens) 		9 / 10 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 PEG  A 201 (-4.4A)
None
PEG  A 201 ( 3.9A)
PEG  A 201 (-3.6A)
PEG  A 201 (-3.8A)
PEG  A 201 (-3.7A)
None
None
None
 0.71A 6mkeD-2pbcA:
15.3		 6mkeD-2pbcA:
56.36