SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2pbf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_RALB600_2
(ESTROGEN RECEPTOR)		 2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE
(Plasmodium
falciparum) 		4 / 6 LEU A 201
ASP A 214
MET A  66
LEU A  94
 None
None
None
SAH  A 301 ( 4.9A)
 1.22A 1errB-2pbfA:
undetectable		 1errB-2pbfA:
21.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JG2_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE
(Plasmodium
falciparum) 		7 / 12 GLY A  88
GLY A  90
GLU A 116
LEU A 121
ALA A 170
VAL A 222
LEU A 224
 SAH  A 301 (-3.1A)
SAH  A 301 (-3.4A)
SAH  A 301 (-2.8A)
SAH  A 301 ( 4.1A)
SAH  A 301 ( 3.8A)
SAH  A 301 (-4.5A)
SAH  A 301 (-4.3A)
 0.25A 1jg2A-2pbfA:
28.3		 1jg2A-2pbfA:
32.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JG3_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE
(Plasmodium
falciparum) 		6 / 11 GLY A  88
GLY A  90
GLU A 116
ARG A 117
LEU A 121
LEU A 224
 SAH  A 301 (-3.1A)
SAH  A 301 (-3.4A)
SAH  A 301 (-2.8A)
None
SAH  A 301 ( 4.1A)
SAH  A 301 (-4.3A)
 0.27A 1jg3A-2pbfA:
28.7		 1jg3A-2pbfA:
32.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JG3_B_ADNB550_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE
(Plasmodium
falciparum) 		6 / 11 GLY A  88
GLY A  90
GLU A 116
ARG A 117
LEU A 121
LEU A 224
 SAH  A 301 (-3.1A)
SAH  A 301 (-3.4A)
SAH  A 301 (-2.8A)
None
SAH  A 301 ( 4.1A)
SAH  A 301 (-4.3A)
 0.29A 1jg3B-2pbfA:
28.7		 1jg3B-2pbfA:
32.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JG4_A_SAMA500_0
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE
(Plasmodium
falciparum) 		6 / 12 THR A  60
SER A  62
GLY A  90
ALA A 170
VAL A 222
LEU A 224
 None
SAH  A 301 (-3.4A)
SAH  A 301 (-3.4A)
SAH  A 301 ( 3.8A)
SAH  A 301 (-4.5A)
SAH  A 301 (-4.3A)
 0.47A 1jg4A-2pbfA:
28.5		 1jg4A-2pbfA:
32.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JG4_A_SAMA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE
(Plasmodium
falciparum) 		5 / 8 GLY A  88
SER A  91
GLU A 116
ARG A 117
LEU A 121
 SAH  A 301 (-3.1A)
SAH  A 301 (-2.8A)
SAH  A 301 (-2.8A)
None
SAH  A 301 ( 4.1A)
 0.19A 1jg4A-2pbfA:
28.5		 1jg4A-2pbfA:
32.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_A_RBFA501_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE
(Plasmodium
falciparum) 		5 / 12 LEU A 201
ILE A 190
ILE A  75
LEU A  74
HIS A  67
 None
None
None
None
SAH  A 301 (-3.9A)
 1.15A 1kyvA-2pbfA:
undetectable
1kyvE-2pbfA:
undetectable		 1kyvA-2pbfA:
21.49
1kyvE-2pbfA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_C_RBFC503_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE
(Plasmodium
falciparum) 		5 / 12 ILE A  75
LEU A  74
HIS A  67
LEU A 201
ILE A 190
 None
None
SAH  A 301 (-3.9A)
None
None
 1.20A 1kyvB-2pbfA:
undetectable
1kyvC-2pbfA:
undetectable		 1kyvB-2pbfA:
21.49
1kyvC-2pbfA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_D_RBFD504_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE
(Plasmodium
falciparum) 		5 / 12 ILE A  75
LEU A  74
HIS A  67
LEU A 201
ILE A 190
 None
None
SAH  A 301 (-3.9A)
None
None
 1.18A 1kyvC-2pbfA:
undetectable
1kyvD-2pbfA:
undetectable		 1kyvC-2pbfA:
21.49
1kyvD-2pbfA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_E_RBFE505_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE
(Plasmodium
falciparum) 		5 / 12 ILE A  75
LEU A  74
HIS A  67
LEU A 201
ILE A 190
 None
None
SAH  A 301 (-3.9A)
None
None
 1.16A 1kyvD-2pbfA:
undetectable
1kyvE-2pbfA:
undetectable		 1kyvD-2pbfA:
21.49
1kyvE-2pbfA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA734_1
(ALPHA AMYLASE)		 2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE
(Plasmodium
falciparum) 		4 / 6 ASN A 128
HIS A  67
TYR A  93
GLY A  90
 None
SAH  A 301 (-3.9A)
None
SAH  A 301 (-3.4A)
 1.22A 1mxdA-2pbfA:
undetectable		 1mxdA-2pbfA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA444_1
(ALPHA AMYLASE)		 2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE
(Plasmodium
falciparum) 		4 / 7 ASN A 128
HIS A  67
TYR A  93
GLY A  90
 None
SAH  A 301 (-3.9A)
None
SAH  A 301 (-3.4A)
 1.23A 1mxgA-2pbfA:
undetectable		 1mxgA-2pbfA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_2
(CES1 PROTEIN)		 2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE
(Plasmodium
falciparum) 		4 / 4 LEU A  94
PRO A  80
ILE A  75
LEU A  74
 SAH  A 301 ( 4.9A)
None
None
None
 1.10A 1ya4B-2pbfA:
undetectable		 1ya4B-2pbfA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_2
(CES1 PROTEIN)		 2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE
(Plasmodium
falciparum) 		4 / 4 LEU A  94
PRO A  80
ILE A  75
LEU A  74
 SAH  A 301 ( 4.9A)
None
None
None
 1.16A 1ya4C-2pbfA:
undetectable		 1ya4C-2pbfA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE
(Plasmodium
falciparum) 		5 / 11 ILE A 113
GLY A 114
THR A  95
ILE A 129
LEU A 126
 None
 1.05A 1z11A-2pbfA:
undetectable		 1z11A-2pbfA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA701_0
(FERROCHELATASE)		 2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE
(Plasmodium
falciparum) 		5 / 12 ILE A  55
SER A  70
LEU A 201
PRO A 192
VAL A 222
 None
None
None
None
SAH  A 301 (-4.5A)
 1.19A 2hrcA-2pbfA:
undetectable		 2hrcA-2pbfA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRH_A_NIOA200_1
(PROTEIN HP0721)		 2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE
(Plasmodium
falciparum) 		4 / 7 GLY A 161
ILE A 113
ARG A  83
LEU A 182
 None
 0.92A 2xrhA-2pbfA:
undetectable		 2xrhA-2pbfA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_O_SAMO302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE
(Plasmodium
falciparum) 		5 / 12 GLY A  88
GLY A  90
SER A  91
LEU A  94
LEU A 224
 SAH  A 301 (-3.1A)
SAH  A 301 (-3.4A)
SAH  A 301 (-2.8A)
SAH  A 301 ( 4.9A)
SAH  A 301 (-4.3A)
 0.86A 3cjtO-2pbfA:
8.8		 3cjtO-2pbfA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKK_A_SAMA301_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE
(Plasmodium
falciparum) 		5 / 12 GLY A  88
GLY A  90
GLU A 116
ASN A 148
LEU A  94
 SAH  A 301 (-3.1A)
SAH  A 301 (-3.4A)
SAH  A 301 (-2.8A)
SAH  A 301 (-3.0A)
SAH  A 301 ( 4.9A)
 0.96A 3ckkA-2pbfA:
7.6		 3ckkA-2pbfA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE201_1
(PROTEIN S100-A4)		 2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE
(Plasmodium
falciparum) 		4 / 7 GLY A  88
MET A  98
CYH A  97
PHE A 142
 SAH  A 301 (-3.1A)
None
None
None
 0.85A 3ko0D-2pbfA:
undetectable
3ko0E-2pbfA:
undetectable		 3ko0D-2pbfA:
16.37
3ko0E-2pbfA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE201_1
(PROTEIN S100-A4)		 2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE
(Plasmodium
falciparum) 		4 / 7 GLY A  90
MET A  98
CYH A  97
PHE A 142
 SAH  A 301 (-3.4A)
None
None
None
 1.05A 3ko0D-2pbfA:
undetectable
3ko0E-2pbfA:
undetectable		 3ko0D-2pbfA:
16.37
3ko0E-2pbfA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP201_1
(PROTEIN S100-A4)		 2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE
(Plasmodium
falciparum) 		4 / 7 GLY A  88
MET A  98
CYH A  97
PHE A 142
 SAH  A 301 (-3.1A)
None
None
None
 0.88A 3ko0M-2pbfA:
0.0
3ko0P-2pbfA:
undetectable		 3ko0M-2pbfA:
16.37
3ko0P-2pbfA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ201_1
(PROTEIN S100-A4)		 2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE
(Plasmodium
falciparum) 		4 / 8 GLY A  88
MET A  98
CYH A  97
PHE A 142
 SAH  A 301 (-3.1A)
None
None
None
 0.88A 3ko0O-2pbfA:
undetectable
3ko0Q-2pbfA:
undetectable		 3ko0O-2pbfA:
16.37
3ko0Q-2pbfA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID801_0
(GLUTAMATE RECEPTOR 2)		 2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE
(Plasmodium
falciparum) 		4 / 8 ILE A 191
PRO A 176
SER A 173
SER A 223
 None
 0.88A 3lslA-2pbfA:
undetectable
3lslD-2pbfA:
undetectable		 3lslA-2pbfA:
21.38
3lslD-2pbfA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_A_PFLA319_1
(GLR4197 PROTEIN)		 2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE
(Plasmodium
falciparum) 		4 / 7 PRO A 176
ILE A 149
LEU A 115
ILE A 166
 None
SAH  A 301 (-4.3A)
None
None
 0.89A 3p50A-2pbfA:
undetectable		 3p50A-2pbfA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_B_PFLB319_1
(GLR4197 PROTEIN)		 2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE
(Plasmodium
falciparum) 		4 / 7 PRO A 176
ILE A 149
LEU A 115
ILE A 166
 None
SAH  A 301 (-4.3A)
None
None
 0.90A 3p50B-2pbfA:
undetectable		 3p50B-2pbfA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_C_PFLC319_1
(GLR4197 PROTEIN)		 2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE
(Plasmodium
falciparum) 		4 / 7 PRO A 176
ILE A 149
LEU A 115
ILE A 166
 None
SAH  A 301 (-4.3A)
None
None
 0.88A 3p50C-2pbfA:
undetectable		 3p50C-2pbfA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_D_PFLD320_1
(GLR4197 PROTEIN)		 2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE
(Plasmodium
falciparum) 		4 / 7 PRO A 176
ILE A 149
LEU A 115
ILE A 166
 None
SAH  A 301 (-4.3A)
None
None
 0.89A 3p50D-2pbfA:
undetectable		 3p50D-2pbfA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_E_PFLE319_1
(GLR4197 PROTEIN)		 2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE
(Plasmodium
falciparum) 		4 / 7 PRO A 176
ILE A 149
LEU A 115
ILE A 166
 None
SAH  A 301 (-4.3A)
None
None
 0.89A 3p50E-2pbfA:
undetectable		 3p50E-2pbfA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_A_SAMA801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE
(Plasmodium
falciparum) 		5 / 12 GLY A  90
SER A  89
THR A  95
VAL A  53
ASN A 128
 SAH  A 301 (-3.4A)
None
None
None
None
 1.19A 3v8vA-2pbfA:
4.2		 3v8vA-2pbfA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_A_SAMA801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE
(Plasmodium
falciparum) 		5 / 12 ILE A 129
GLY A  90
SER A  89
THR A  95
VAL A  53
 None
SAH  A 301 (-3.4A)
None
None
None
 1.14A 3v8vA-2pbfA:
4.2		 3v8vA-2pbfA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_2
(ADENOSINE KINASE)		 2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE
(Plasmodium
falciparum) 		4 / 5 LEU A 105
ILE A 129
ALA A  99
PHE A 142
 None
 0.95A 4dc3B-2pbfA:
2.6		 4dc3B-2pbfA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G5J_A_0WMA1102_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE
(Plasmodium
falciparum) 		4 / 7 PHE A 221
HIS A 167
ILE A 166
PRO A 192
 None
 1.18A 4g5jA-2pbfA:
undetectable		 4g5jA-2pbfA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE
(Plasmodium
falciparum) 		4 / 6 ASP A  28
ASN A 103
ASN A  32
GLN A  36
 None
 1.26A 5l6eA-2pbfA:
2.0		 5l6eA-2pbfA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MFX_A_ACTA701_0
(GENOME POLYPROTEIN)		 2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE
(Plasmodium
falciparum) 		4 / 5 ARG A  39
HIS A  67
ALA A  63
ASP A  50
 None
SAH  A 301 (-3.9A)
None
None
 1.42A 5mfxA-2pbfA:
undetectable		 5mfxA-2pbfA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE
(Plasmodium
falciparum) 		5 / 12 LEU A 160
ILE A  85
ILE A 193
LEU A 175
ILE A 178
 None
 1.18A 5y2tB-2pbfA:
undetectable		 5y2tB-2pbfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_B_SAMB601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE
(Plasmodium
falciparum) 		4 / 7 GLY A  90
GLY A  92
GLU A 116
ASN A 148
 SAH  A 301 (-3.4A)
None
SAH  A 301 (-2.8A)
SAH  A 301 (-3.0A)
 0.52A 5ybbB-2pbfA:
9.0		 5ybbB-2pbfA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3A_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE
(Plasmodium
falciparum) 		5 / 12 HIS A 146
GLY A  90
GLY A  88
ILE A  55
LEU A 121
 None
SAH  A 301 (-3.4A)
SAH  A 301 (-3.1A)
None
SAH  A 301 ( 4.1A)
 0.85A 6b3aA-2pbfA:
6.9		 6b3aA-2pbfA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3B_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE
(Plasmodium
falciparum) 		5 / 12 HIS A 146
GLY A  90
GLY A  88
ILE A  55
LEU A 121
 None
SAH  A 301 (-3.4A)
SAH  A 301 (-3.1A)
None
SAH  A 301 ( 4.1A)
 0.89A 6b3bA-2pbfA:
6.6		 6b3bA-2pbfA:
17.80