SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2pbi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FIQ_C_SALC1335_1
(XANTHINE OXIDASE)		 2pbi GUANINE
NUCLEOTIDE-BINDING
PROTEIN SUBUNIT BETA
5
(Mus
musculus) 		4 / 8 LEU B 268
PHE B 235
VAL B 274
LEU B 265
 None
 0.92A 1fiqC-2pbiB:
undetectable		 1fiqC-2pbiB:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3004_1
(SERUM ALBUMIN)		 2pbi GUANINE
NUCLEOTIDE-BINDING
PROTEIN SUBUNIT BETA
5
REGULATOR OF
G-PROTEIN SIGNALING
9
(Mus
musculus) 		4 / 7 GLU A 333
LEU A 335
VAL A 343
LEU B 188
 None
 1.01A 1hk3A-2pbiA:
1.4		 1hk3A-2pbiA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_D_URFD2021_1
(URIDINE
PHOSPHORYLASE)		 2pbi REGULATOR OF
G-PROTEIN SIGNALING
9
(Mus
musculus) 		4 / 7 GLY A  74
GLN A  71
ILE A  83
VAL A  78
 None
 1.03A 1rxcD-2pbiA:
undetectable		 1rxcD-2pbiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)		 2pbi REGULATOR OF
G-PROTEIN SIGNALING
9
(Mus
musculus) 		4 / 7 GLY A  74
GLN A  71
ILE A  83
VAL A  78
 None
 1.06A 1rxcF-2pbiA:
undetectable		 1rxcF-2pbiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 2pbi REGULATOR OF
G-PROTEIN SIGNALING
9
(Mus
musculus) 		4 / 7 GLY A  74
GLN A  71
ILE A  83
VAL A  78
 None
 1.05A 1rxcL-2pbiA:
undetectable		 1rxcL-2pbiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_A_SALA501_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 2pbi GUANINE
NUCLEOTIDE-BINDING
PROTEIN SUBUNIT BETA
5
(Mus
musculus) 		5 / 9 ALA B 171
SER B 214
LEU B 201
LEU B 169
HIS B 194
 None
 1.42A 1y7iA-2pbiB:
undetectable		 1y7iA-2pbiB:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_B_SALB503_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 2pbi GUANINE
NUCLEOTIDE-BINDING
PROTEIN SUBUNIT BETA
5
(Mus
musculus) 		5 / 10 ALA B 171
SER B 214
LEU B 201
LEU B 169
HIS B 194
 None
 1.41A 1y7iB-2pbiB:
undetectable		 1y7iB-2pbiB:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_B_SALB503_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 2pbi GUANINE
NUCLEOTIDE-BINDING
PROTEIN SUBUNIT BETA
5
(Mus
musculus) 		5 / 10 ALA B 171
SER B 214
LEU B 201
PHE B 212
HIS B 194
 None
 1.39A 1y7iB-2pbiB:
undetectable		 1y7iB-2pbiB:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4478_1
(NEURAMINIDASE)		 2pbi GUANINE
NUCLEOTIDE-BINDING
PROTEIN SUBUNIT BETA
5
(Mus
musculus) 		4 / 8 SER B 258
ASP B 260
SER B 240
ASN B 243
 None
 1.13A 2cmlD-2pbiB:
9.3		 2cmlD-2pbiB:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 2pbi GUANINE
NUCLEOTIDE-BINDING
PROTEIN SUBUNIT BETA
5
(Mus
musculus) 		5 / 12 HIS B  62
ALA B 112
CYH B 111
VAL B  87
TYR B 132
 None
 1.42A 2g70B-2pbiB:
undetectable		 2g70B-2pbiB:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)		 2pbi REGULATOR OF
G-PROTEIN SIGNALING
9
(Mus
musculus) 		5 / 12 ILE A 365
VAL A 384
LEU A 377
ALA A 331
PHE A 328
 None
 1.47A 2jj8C-2pbiA:
undetectable		 2jj8C-2pbiA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q2H_B_ACTB501_0
(SECRETION CHAPERONE,
PHAGE-DISPLAY
DERIVED PEPTIDE)		 2pbi REGULATOR OF
G-PROTEIN SIGNALING
9
(Mus
musculus) 		3 / 3 ARG A 102
SER A  45
TYR A  84
 None
 0.67A 2q2hA-2pbiA:
undetectable
2q2hB-2pbiA:
undetectable		 2q2hA-2pbiA:
13.44
2q2hB-2pbiA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_A_QPSA1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 2pbi GUANINE
NUCLEOTIDE-BINDING
PROTEIN SUBUNIT BETA
5
(Mus
musculus) 		5 / 12 PHE B 254
ASN B 243
VAL B 242
GLY B 216
ALA B 221
 None
 1.19A 2x2iA-2pbiB:
3.2		 2x2iA-2pbiB:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_C_QPSC1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 2pbi GUANINE
NUCLEOTIDE-BINDING
PROTEIN SUBUNIT BETA
5
(Mus
musculus) 		5 / 12 PHE B 254
ASN B 243
VAL B 242
GLY B 216
ALA B 221
 None
 1.19A 2x2iC-2pbiB:
3.2		 2x2iC-2pbiB:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CSJ_B_CBLB211_0
(GLUTATHIONE
S-TRANSFERASE P)		 2pbi GUANINE
NUCLEOTIDE-BINDING
PROTEIN SUBUNIT BETA
5
(Mus
musculus) 		5 / 9 PHE B 254
VAL B 245
GLY B 257
ARG B 264
GLY B 215
 None
 1.17A 3csjB-2pbiB:
undetectable		 3csjB-2pbiB:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B304_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 2pbi GUANINE
NUCLEOTIDE-BINDING
PROTEIN SUBUNIT BETA
5
REGULATOR OF
G-PROTEIN SIGNALING
9
(Mus
musculus) 		4 / 5 ASN A 198
THR B 348
SER B 344
ARG B 350
 None
 1.02A 3hlwB-2pbiA:
undetectable		 3hlwB-2pbiA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_A_URFA254_1
(URIDINE
PHOSPHORYLASE)		 2pbi REGULATOR OF
G-PROTEIN SIGNALING
9
(Mus
musculus) 		4 / 6 GLY A  74
GLN A  71
ILE A  83
VAL A  78
 None
 1.10A 3kvvA-2pbiA:
undetectable		 3kvvA-2pbiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)		 2pbi REGULATOR OF
G-PROTEIN SIGNALING
9
(Mus
musculus) 		4 / 6 GLY A  74
GLN A  71
ILE A  83
VAL A  78
 None
 1.08A 3kvvB-2pbiA:
undetectable		 3kvvB-2pbiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)		 2pbi REGULATOR OF
G-PROTEIN SIGNALING
9
(Mus
musculus) 		4 / 6 GLY A  74
GLN A  71
ILE A  83
VAL A  78
 None
 1.10A 3kvvC-2pbiA:
undetectable		 3kvvC-2pbiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_D_URFD254_1
(URIDINE
PHOSPHORYLASE)		 2pbi REGULATOR OF
G-PROTEIN SIGNALING
9
(Mus
musculus) 		4 / 6 GLY A  74
GLN A  71
ILE A  83
VAL A  78
 None
 1.14A 3kvvD-2pbiA:
undetectable		 3kvvD-2pbiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_E_URFE254_1
(URIDINE
PHOSPHORYLASE)		 2pbi REGULATOR OF
G-PROTEIN SIGNALING
9
(Mus
musculus) 		4 / 6 GLY A  74
GLN A  71
ILE A  83
VAL A  78
 None
 1.10A 3kvvE-2pbiA:
undetectable		 3kvvE-2pbiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_F_URFF254_1
(URIDINE
PHOSPHORYLASE)		 2pbi REGULATOR OF
G-PROTEIN SIGNALING
9
(Mus
musculus) 		4 / 6 GLY A  74
GLN A  71
ILE A  83
VAL A  78
 None
 1.08A 3kvvF-2pbiA:
undetectable		 3kvvF-2pbiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA278_0
(UNIVERSAL STRESS
PROTEIN)		 2pbi REGULATOR OF
G-PROTEIN SIGNALING
9
GUANINE
NUCLEOTIDE-BINDING
PROTEIN SUBUNIT BETA
5
(Mus
musculus;
Mus
musculus) 		3 / 3 SER A 251
GLY B 295
SER B 250
 None
 0.59A 3loqA-2pbiA:
undetectable		 3loqA-2pbiA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5V_A_ACTA511_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2pbi REGULATOR OF
G-PROTEIN SIGNALING
9
(Mus
musculus) 		4 / 4 ASN A 257
PHE A 254
SER A 256
GLN A 253
 None
 1.22A 3v5vA-2pbiA:
0.0		 3v5vA-2pbiA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2pbi REGULATOR OF
G-PROTEIN SIGNALING
9
GUANINE
NUCLEOTIDE-BINDING
PROTEIN SUBUNIT BETA
5
(Mus
musculus;
Mus
musculus) 		5 / 12 ILE A 247
SER B 292
VAL B 309
LEU B  48
VAL B 318
 None
None
None
GOL  A 905 ( 3.4A)
None
 1.10A 3w68B-2pbiA:
undetectable		 3w68B-2pbiA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		 2pbi GUANINE
NUCLEOTIDE-BINDING
PROTEIN SUBUNIT BETA
5
REGULATOR OF
G-PROTEIN SIGNALING
9
(Mus
musculus) 		3 / 3 ASP A 386
GLY B 209
TYR A 383
 None
 0.72A 3w9tC-2pbiA:
undetectable		 3w9tC-2pbiA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		 2pbi GUANINE
NUCLEOTIDE-BINDING
PROTEIN SUBUNIT BETA
5
REGULATOR OF
G-PROTEIN SIGNALING
9
(Mus
musculus) 		3 / 3 ASP A 386
GLY B 209
TYR A 383
 None
 0.71A 3w9tG-2pbiA:
undetectable		 3w9tG-2pbiA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7N_A_ZMRA601_2
(NEURAMINIDASE)		 2pbi REGULATOR OF
G-PROTEIN SIGNALING
9
(Mus
musculus) 		3 / 3 ARG A 292
ARG A 295
TRP A 296
 None
 1.45A 4b7nA-2pbiA:
undetectable		 4b7nA-2pbiA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 2pbi REGULATOR OF
G-PROTEIN SIGNALING
9
GUANINE
NUCLEOTIDE-BINDING
PROTEIN SUBUNIT BETA
5
(Mus
musculus;
Mus
musculus) 		5 / 12 LYS A 224
HIS B 194
HIS B 152
ASP B 174
GLY B 216
 None
 1.14A 4blvA-2pbiA:
undetectable		 4blvA-2pbiA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_B_CAMB423_0
(CYTOCHROME P450)		 2pbi REGULATOR OF
G-PROTEIN SIGNALING
9
GUANINE
NUCLEOTIDE-BINDING
PROTEIN SUBUNIT BETA
5
(Mus
musculus;
Mus
musculus) 		5 / 10 TYR B 155
THR A 209
LEU B 199
GLY B 216
ASP B 174
 None
 1.35A 4c9pB-2pbiB:
undetectable		 4c9pB-2pbiB:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_2
(NEURAMINIDASE)		 2pbi REGULATOR OF
G-PROTEIN SIGNALING
9
(Mus
musculus) 		3 / 3 ARG A 292
ARG A 295
TRP A 296
 None
 1.47A 4cpzC-2pbiA:
undetectable		 4cpzC-2pbiA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_2
(NEURAMINIDASE)		 2pbi REGULATOR OF
G-PROTEIN SIGNALING
9
(Mus
musculus) 		3 / 3 ARG A 292
ARG A 295
TRP A 296
 None
 1.39A 4cpzE-2pbiA:
undetectable		 4cpzE-2pbiA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_F_ZMRF1470_2
(NEURAMINIDASE)		 2pbi REGULATOR OF
G-PROTEIN SIGNALING
9
(Mus
musculus) 		3 / 3 ARG A 292
ARG A 295
TRP A 296
 None
 1.47A 4cpzF-2pbiA:
undetectable		 4cpzF-2pbiA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_G_ZMRG1471_2
(NEURAMINIDASE)		 2pbi REGULATOR OF
G-PROTEIN SIGNALING
9
(Mus
musculus) 		3 / 3 ARG A 292
ARG A 295
TRP A 296
 None
 1.45A 4cpzG-2pbiA:
undetectable		 4cpzG-2pbiA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_H_ZMRH1470_2
(NEURAMINIDASE)		 2pbi REGULATOR OF
G-PROTEIN SIGNALING
9
(Mus
musculus) 		3 / 3 ARG A 292
ARG A 295
TRP A 296
 None
 1.46A 4cpzH-2pbiA:
undetectable		 4cpzH-2pbiA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_B_TCWB1126_1
(TRANSTHYRETIN)		 2pbi GUANINE
NUCLEOTIDE-BINDING
PROTEIN SUBUNIT BETA
5
(Mus
musculus) 		4 / 7 LEU B 187
THR B 176
ALA B 178
THR B 170
 None
 0.99A 4d7bA-2pbiB:
undetectable		 4d7bA-2pbiB:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_F_URFF1301_1
(URIDINE
PHOSPHORYLASE)		 2pbi REGULATOR OF
G-PROTEIN SIGNALING
9
(Mus
musculus) 		4 / 6 GLY A  74
GLN A  71
ILE A  83
VAL A  78
 None
 1.05A 4e1vF-2pbiA:
undetectable		 4e1vF-2pbiA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_G_URFG1301_1
(URIDINE
PHOSPHORYLASE)		 2pbi REGULATOR OF
G-PROTEIN SIGNALING
9
(Mus
musculus) 		4 / 8 GLY A  74
GLN A  71
ILE A  83
VAL A  78
 None
 0.99A 4e1vG-2pbiA:
undetectable		 4e1vG-2pbiA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_A_CCSA109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 2pbi GUANINE
NUCLEOTIDE-BINDING
PROTEIN SUBUNIT BETA
5
(Mus
musculus) 		4 / 8 VAL B 182
ILE B 168
SER B 130
ALA B 110
 None
 0.98A 4eyzA-2pbiB:
undetectable		 4eyzA-2pbiB:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_B_CCSB109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 2pbi GUANINE
NUCLEOTIDE-BINDING
PROTEIN SUBUNIT BETA
5
(Mus
musculus) 		4 / 8 VAL B 182
ILE B 168
SER B 130
ALA B 110
 None
 0.98A 4eyzB-2pbiB:
undetectable		 4eyzB-2pbiB:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 2pbi GUANINE
NUCLEOTIDE-BINDING
PROTEIN SUBUNIT BETA
5
REGULATOR OF
G-PROTEIN SIGNALING
9
(Mus
musculus) 		5 / 12 VAL A 200
PHE B 284
PHE A  16
LEU A  23
VAL A  24
 None
 1.21A 4ib4A-2pbiA:
2.5		 4ib4A-2pbiA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_B_9TPB601_2
(SERUM ALBUMIN)		 2pbi GUANINE
NUCLEOTIDE-BINDING
PROTEIN SUBUNIT BETA
5
REGULATOR OF
G-PROTEIN SIGNALING
9
(Mus
musculus) 		4 / 4 ARG A 207
GLU A 213
ASP B 259
ARG A  13
 None
 1.32A 4l9qB-2pbiA:
1.3		 4l9qB-2pbiA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_A_BRLA501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2pbi GUANINE
NUCLEOTIDE-BINDING
PROTEIN SUBUNIT BETA
5
REGULATOR OF
G-PROTEIN SIGNALING
9
(Mus
musculus) 		4 / 5 GLY B 295
LEU B  48
ILE A 260
LEU B  38
 None
GOL  A 905 ( 3.4A)
None
None
 0.86A 4o8fA-2pbiB:
undetectable		 4o8fA-2pbiB:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_B_ML1B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2pbi GUANINE
NUCLEOTIDE-BINDING
PROTEIN SUBUNIT BETA
5
REGULATOR OF
G-PROTEIN SIGNALING
9
(Mus
musculus) 		5 / 11 GLY A  74
ILE A  83
PHE A  16
ILE A  20
PHE B 284
 None
 1.17A 4qoiA-2pbiA:
undetectable
4qoiB-2pbiA:
undetectable		 4qoiA-2pbiA:
19.11
4qoiB-2pbiA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_1
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 2pbi GUANINE
NUCLEOTIDE-BINDING
PROTEIN SUBUNIT BETA
5
(Mus
musculus) 		3 / 3 SER B 256
TYR B 266
ASP B 260
 None
 0.65A 4rp8C-2pbiB:
undetectable		 4rp8C-2pbiB:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_A_DM2A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2pbi GUANINE
NUCLEOTIDE-BINDING
PROTEIN SUBUNIT BETA
5
REGULATOR OF
G-PROTEIN SIGNALING
9
(Mus
musculus) 		5 / 12 GLY A  74
ILE A  83
PHE A  16
ILE A  20
PHE B 284
 None
 1.21A 4zvmA-2pbiA:
undetectable
4zvmB-2pbiA:
undetectable		 4zvmA-2pbiA:
19.16
4zvmB-2pbiA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA617_0
(SERUM ALBUMIN)		 2pbi REGULATOR OF
G-PROTEIN SIGNALING
9
(Mus
musculus) 		3 / 3 TRP A  58
ARG A  62
LEU A  73
 None
 0.71A 5dbyA-2pbiA:
1.2		 5dbyA-2pbiA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 2pbi GUANINE
NUCLEOTIDE-BINDING
PROTEIN SUBUNIT BETA
5
(Mus
musculus) 		5 / 12 PHE B 299
VAL B 318
LEU B  48
SER B 294
ARG B 296
 None
None
GOL  A 905 ( 3.4A)
None
None
 1.12A 5hbsA-2pbiB:
undetectable		 5hbsA-2pbiB:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA303_1
(CHITOSANASE)		 2pbi GUANINE
NUCLEOTIDE-BINDING
PROTEIN SUBUNIT BETA
5
(Mus
musculus) 		4 / 5 HIS B 192
VAL B 198
GLY B 195
ALA B 196
 None
 1.00A 5hwaA-2pbiB:
undetectable		 5hwaA-2pbiB:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K50_A_ACTA1403_0
(L-THREONINE
3-DEHYDROGENASE)		 2pbi GUANINE
NUCLEOTIDE-BINDING
PROTEIN SUBUNIT BETA
5
(Mus
musculus) 		4 / 5 SER B 256
VAL B 245
GLY B 215
ALA B 221
 None
 0.59A 5k50A-2pbiB:
undetectable		 5k50A-2pbiB:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K50_A_ACTA1403_0
(L-THREONINE
3-DEHYDROGENASE)		 2pbi GUANINE
NUCLEOTIDE-BINDING
PROTEIN SUBUNIT BETA
5
(Mus
musculus) 		4 / 5 SER B 288
VAL B 289
GLY B 257
ALA B 286
 None
 1.08A 5k50A-2pbiB:
undetectable		 5k50A-2pbiB:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_A_SAMA301_0
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 2pbi REGULATOR OF
G-PROTEIN SIGNALING
9
GUANINE
NUCLEOTIDE-BINDING
PROTEIN SUBUNIT BETA
5
(Mus
musculus;
Mus
musculus) 		5 / 12 GLY B 195
TYR A 228
ASP B 218
ALA B 196
ASP B 197
 None
 1.19A 5kvaA-2pbiB:
undetectable		 5kvaA-2pbiB:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4E_D_EDPD402_1
(PROTON-GATED ION
CHANNEL)		 2pbi GUANINE
NUCLEOTIDE-BINDING
PROTEIN SUBUNIT BETA
5
(Mus
musculus) 		4 / 8 SER B 342
THR B 348
SER B 344
THR B  55
 None
 0.95A 5l4eA-2pbiB:
undetectable
5l4eB-2pbiB:
undetectable
5l4eC-2pbiB:
undetectable
5l4eD-2pbiB:
undetectable
5l4eE-2pbiB:
undetectable		 5l4eA-2pbiB:
20.84
5l4eB-2pbiB:
20.84
5l4eC-2pbiB:
20.84
5l4eD-2pbiB:
20.84
5l4eE-2pbiB:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4E_D_EDPD402_1
(PROTON-GATED ION
CHANNEL)		 2pbi GUANINE
NUCLEOTIDE-BINDING
PROTEIN SUBUNIT BETA
5
(Mus
musculus) 		4 / 8 THR B  55
SER B 342
THR B 348
SER B 344
 None
 0.91A 5l4eA-2pbiB:
undetectable
5l4eB-2pbiB:
undetectable
5l4eC-2pbiB:
undetectable
5l4eD-2pbiB:
undetectable
5l4eE-2pbiB:
undetectable		 5l4eA-2pbiB:
20.84
5l4eB-2pbiB:
20.84
5l4eC-2pbiB:
20.84
5l4eD-2pbiB:
20.84
5l4eE-2pbiB:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_B_CVIB603_0
(ACETYLCHOLINESTERASE)		 2pbi GUANINE
NUCLEOTIDE-BINDING
PROTEIN SUBUNIT BETA
5
(Mus
musculus) 		4 / 7 TYR B 266
GLN B 233
ASP B 271
HIS B  34
 None
 0.99A 5ov9B-2pbiB:
undetectable		 5ov9B-2pbiB:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_1
(REGULATORY PROTEIN
TETR)		 2pbi GUANINE
NUCLEOTIDE-BINDING
PROTEIN SUBUNIT BETA
5
(Mus
musculus) 		4 / 8 GLY B 215
ARG B 246
VAL B 213
ASP B 202
 None
GOL  B 902 (-2.9A)
None
None
 1.04A 5vlmA-2pbiB:
undetectable		 5vlmA-2pbiB:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_A_RBFA502_2
(RIBOFLAVIN LYASE)		 2pbi GUANINE
NUCLEOTIDE-BINDING
PROTEIN SUBUNIT BETA
5
REGULATOR OF
G-PROTEIN SIGNALING
9
(Mus
musculus) 		4 / 5 ASN B 243
ASP B 241
SER B 240
ARG A  13
 None
 1.34A 5w4zA-2pbiB:
undetectable		 5w4zA-2pbiB:
12.97