SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2pbx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_RALB600_2
(ESTROGEN RECEPTOR)		 2pbx HEMAGGLUTININ/PROTEA
SE REGULATORY
PROTEIN
(Vibrio
cholerae) 		4 / 6 LEU A  80
MET A 101
LEU A 112
HIS A 168
 None
 1.27A 1errB-2pbxA:
undetectable		 1errB-2pbxA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_2
(ESTROGEN RECEPTOR)		 2pbx HEMAGGLUTININ/PROTEA
SE REGULATORY
PROTEIN
(Vibrio
cholerae) 		4 / 5 LEU A  80
MET A 101
LEU A 112
HIS A 168
 None
 1.26A 2jfaA-2pbxA:
undetectable		 2jfaA-2pbxA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAW_A_SUZA91_1
(SEGMENT POLARITY
PROTEIN DISHEVELLED
HOMOLOG DVL-1)		 2pbx HEMAGGLUTININ/PROTEA
SE REGULATORY
PROTEIN
(Vibrio
cholerae) 		5 / 11 GLY A 169
ILE A 170
SER A 173
ILE A 174
VAL A 102
 None
 1.00A 2kawA-2pbxA:
undetectable		 2kawA-2pbxA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_2
(ESTROGEN RECEPTOR)		 2pbx HEMAGGLUTININ/PROTEA
SE REGULATORY
PROTEIN
(Vibrio
cholerae) 		4 / 5 LEU A  80
MET A 101
LEU A 112
HIS A 168
 None
 1.24A 2qxsA-2pbxA:
undetectable		 2qxsA-2pbxA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_2
(ESTROGEN RECEPTOR)		 2pbx HEMAGGLUTININ/PROTEA
SE REGULATORY
PROTEIN
(Vibrio
cholerae) 		4 / 5 LEU A  80
MET A 101
LEU A 112
HIS A 168
 None
 1.25A 2qxsB-2pbxA:
undetectable		 2qxsB-2pbxA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_B_ACTB1463_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 2pbx HEMAGGLUTININ/PROTEA
SE REGULATORY
PROTEIN
(Vibrio
cholerae) 		4 / 7 VAL A  54
ILE A  43
ALA A  47
VAL A  49
 None
 0.43A 2xrzB-2pbxA:
undetectable		 2xrzB-2pbxA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUH_A_ACTA610_0
(SERUM ALBUMIN)		 2pbx HEMAGGLUTININ/PROTEA
SE REGULATORY
PROTEIN
(Vibrio
cholerae) 		3 / 3 VAL A  49
SER A  50
THR A  53
 None
 0.36A 4luhA-2pbxA:
4.3		 4luhA-2pbxA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_2
(ESTROGEN RECEPTOR)		 2pbx HEMAGGLUTININ/PROTEA
SE REGULATORY
PROTEIN
(Vibrio
cholerae) 		4 / 5 LEU A  80
MET A 101
LEU A 112
HIS A 168
 None
 1.26A 4xi3B-2pbxA:
undetectable		 4xi3B-2pbxA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_2
(CYTOCHROME P450 3A5)		 2pbx HEMAGGLUTININ/PROTEA
SE REGULATORY
PROTEIN
(Vibrio
cholerae) 		3 / 3 ARG A  33
PHE A  71
LEU A  64
 None
 0.67A 5veuA-2pbxA:
undetectable		 5veuA-2pbxA:
17.80