SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2pcp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D9L_A_ACTA501_0
(CTD-PEPTIDE
RNA-BINDING PROTEIN
16)		 2pcp IMMUNOGLOBULIN
(Mus
musculus) 		4 / 5 ILE B  34
PRO B  52
TYR B  52
TYR B  33
 None
None
None
1PC  B 227 ( 3.5A)
 0.97A 3d9lA-2pcpB:
undetectable
3d9lY-2pcpB:
undetectable		 3d9lA-2pcpB:
20.27
3d9lY-2pcpB:
6.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUG_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2pcp IMMUNOGLOBULIN
(Mus
musculus) 		5 / 12 ALA B  24
PHE B  29
THR B  77
ALA B  78
ASP B  72
 None
 1.02A 3sugA-2pcpB:
undetectable		 3sugA-2pcpB:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD392_1
(TETX2 PROTEIN)		 2pcp IMMUNOGLOBULIN
(Mus
musculus) 		4 / 5 HIS B  41
SER B  87
SER B  84
VAL B 111
 None
 1.33A 4a99D-2pcpB:
undetectable		 4a99D-2pcpB:
17.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MTH_A_ACTA302_0
(ANTIBODY FAB HEAVY
CHAIN)		 2pcp IMMUNOGLOBULIN
(Mus
musculus) 		5 / 5 SER B 112
ALA B 114
PHE B 148
LEU B 178
ASP B 183
 None
 0.90A 5mthA-2pcpB:
27.1		 5mthA-2pcpB:
81.19