SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2pd1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT6_B_DESB128_1
(TRANSTHYRETIN)		 2pd1 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		4 / 5 LEU A  81
ALA A  79
LEU A  82
SER A  84
 None
 1.06A 1tt6B-2pd1A:
undetectable		 1tt6B-2pd1A:
26.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB514_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 2pd1 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 ALA A  42
ILE A  70
PHE A  23
LEU A  20
LEU A  82
 None
ACT  A 501 (-3.6A)
None
None
None
 1.12A 3k2hB-2pd1A:
undetectable		 3k2hB-2pd1A:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 2pd1 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 ALA A  64
GLY A  68
ALA A  60
GLY A  36
SER A  35
 None
 1.31A 5jglB-2pd1A:
undetectable		 5jglB-2pd1A:
17.07